Uses of Daclarit

Daclarit belongs to the group of antiparasitic, anti-infective, anti-viral, anti-fungal drugs. The drug is indicated for the treatment of common bacterial infections. Let's find out information about Daclarit drug in the following article.

Daclarit contains Clarithromycin 250mg and other excipients just enough for 1 tablet provided by the manufacturer. The drug is prepared in the form of film-coated tablets, packaged in a box of 2 blisters, each blister has 10 tablets.

Daclarit is indicated for the treatment of the following cases:
Skin and soft tissue infections. Upper respiratory tract infections such as sinusitis, pharyngitis, otitis media, tonsillitis. Lower respiratory tract infections such as: Acute and chronic bronchitis, pneumonia, COPD exacerbations. Combination treatment of peptic ulcers caused by Helicobacter pylori. Kills bacteria Mycoplasma pneumoniae and Legionella causing pneumonia, diphtheria, early stage of whooping cough, opportunistic infections caused by Mycobacterium. In addition, Daclarit is contraindicated in the following cases:
Patients who are allergic to the active ingredient Clarithromycin or other excipients contained in the drug's ingredients. Patients with history of bradycardia, arrhythmia, heart disease with prolonged QT interval, coronary insufficiency, electrolyte imbalance.

Daclarit is formulated as a film-coated tablet that should be taken orally. The drug should be swallowed whole, the patient should not chew, crush or break the tablet before taking it.
Because the drug is not affected by food, it can be taken before or after a meal without reducing the extent or speed of absorption of the drug.
Below is the dosage of Daclarit drug:
Adults:
Use at a dose of 250mg x 2 times daily, for 7 days continuously or 500mg of adjusted release form once daily. In severe infections it can be increased to 500mg twice daily or 1000mg of the modified release form once daily and continued for up to 14 days. In the case of combination treatment of peptic ulcer caused by Helicobacter pylori, the usual dose is 500mg x 2 times daily, used continuously for 7 days. Patients should be used in combination with Omeprazole 40mg orally twice a day. Children over 12 years old:
Use the same dose as adults. Children under 12 years: Use this drug in the form of emulsions for pediatric patients with specific doses as follows:
The daily dose for children is 7.5mg/kg body weight, 2 times a day until the time of death. The maximum dose is 500mg. The duration of each course of treatment is 7-10 days, depending on the strain of bacteria causing the disease and how severe or mild the disease is. In the case of treatment for strep throat, it is necessary to treat it for at least 10 days. The prepared solution can be taken with or without meals and can be taken with milk. Elderly people:
Use the same dose as adults. Patients with renal impairment:
No dose adjustment is required unless the patient has severe renal impairment (based on creatinine clearance less than 30ml/min. In case of need adjustment, halve the total daily dose. Note: This is a reference dose provided by the manufacturer. Specific dosage will be based on the medical condition and health of each patient so that the doctor can prescribe the appropriate dose.

The doctor always considers the benefit that Daclarit brings to the patient and the possible risk of side effects to prescribe the appropriate drug.
Daclarit drug is quite well tolerated, some side effects that may be encountered when taking the drug are recorded including:
Gastrointestinal disturbances, nausea, vomiting, dyspepsia, diarrhea, abdominal pain. Stomatitis, glomerulonephritis, raised nodules around the mouth. Headache, allergic reactions ranging from urticaria and mild skin rashes to anaphylaxis and, rarely, Stevens-Johnson syndrome. Taste disturbance, loss of color in the tongue. Anxiety, dizziness, insomnia, hallucinations, psychosis, nightmares, confusion. Loss of hearing. Pseudomembranous colitis, liver dysfunction, hepatitis and biliary tract infection with or without associated jaundice. Note: When the patient develops side effects, notify the doctor or medical person immediately.

When used in combination with the following drugs with Daclarit, the following interactions may occur:
Use in combination with drugs used to treat epilepsy: Daclarit inhibits the metabolism of drugs such as Carbamazepine and Phenytoin. their side effects. Daclarit inhibits metabolism leading to prolonged QT interval, torsades de pointes, and ventricular fibrillation. Daclarit inhibits the hepatic metabolism of theophylline and increases its plasma concentration leading to the risk of drug toxicity. It also reduces the absorption of Zidovudine. The use of Daclarit in patients taking warfarin may potentiate its effects. Therefore, prothrombin time should be regularly monitored in these patients. The efficacy of Digoxin may be increased by concomitant administration of Daclarit, so serum levels of Digoxin should be monitored. There may be other interactions of Daclarit with food or other drugs not listed above. Therefore, stop using this medicine and seek medical attention as soon as any unusual reactions occur.
To avoid interactions, before being prescribed Daclarit, patients should inform their doctor about all the drugs they are using, including functional foods.

Some notes when patients take Daclarit drug as follows:
Daclarit drug is excreted mainly by the liver and kidneys. Therefore, caution should be exercised when using this antibiotic in patients with impaired liver or kidney function. Prolonged and repeated use of Daclarit may lead to the development of strains of fungi or bacteria that are no longer susceptible to the drug. In case of superinfection, the patient should be instructed to stop taking the drug and start treatment according to the appropriate regimen. There is a risk of increased serum concentrations of drugs when used in combination with Daclarit which is metabolised by the cytochrome P450 system. Pregnant women: When using Daclarit, there may be potential risks to the fetus such as miscarriage, malformation,... Therefore, use this drug only when prescribed by a doctor. Lactation: The drug is known to be excreted in breast milk, so there is a risk of harm to the nursing infant when taking the drug. In the event that the mother must take this medicine for the treatment, discontinue breast-feeding. Use medication only when prescribed by your doctor.

If you forget to take your medicine, take it as soon as you remember. The drug can be taken about 1-2 hours later than the daily dose. But when it is almost time for the next dose, the missed dose should be thrown away. Patients should absolutely not make up for a double dose. When taking an overdose, patients often experience symptoms such as itching, skin allergies, nausea, vomiting, dizziness, hypotension, convulsions, shortness of breath, respiratory failure, tachycardia... In this case, the drug should be stopped immediately when detecting the above side effects and informing the treating doctor. Family members should take the patient to the hospital for timely examination and treatment. Patients should also bring the medications they have used so that the doctor can get information and handle it quickly and promptly. Hopefully, the above article has provided all the relevant information about the uses, dosage and some notes when using Daclarit. Patients need to take Daclarit medicine exactly as directed by the doctor. Note, Daclarit is a prescription drug, patients can only use this drug when prescribed by a specialist.