Uses of Fonclar

Fonclar drug is used by doctor's prescription to effectively repel bacterial infections such as bronchitis, pneumonia, tonsillitis, ... Patients need to carefully consult their doctor's advice on how to use as well as The dose of medicine is suitable for your health condition to completely overcome the disease.

Fonclar is a preferred solution indicated for the treatment of conditions such as sinusitis, tonsillitis, bronchitis, pneumonia, whooping cough and some other conditions caused by bacteria. Fonclar is prepared and manufactured by Thanh Hoa Pharmaceutical and Medical Equipment Joint Stock Company - Vietnam in the form of long film-coated tablets, each box includes 2 blisters x 10 tablets. The main ingredient in Fonclar is Clarithromycin 250mg. In addition, the manufacturer also adds other auxiliary excipients with sufficient content. To use Fonclar effectively and completely treat the disease, you need to strictly follow all the instructions of your doctor. Avoid self-medication without your doctor's approval.

2.1. Uses of Clarithromycin Clarithromycin is known as a semi-synthetic Macrolide, has good bacteriostatic ability and destroys very sensitive strains of bacteria when used in high doses. It has been shown that Clarithromycin inhibits protein synthesis of susceptible bacteria through binding to 50S ribosomal subunits.
In general, the site of action of Clarithromycin is similar to that of Lincomycin, Clindamycin, Erythromycin and Chloramphenicol. However, it is slightly more active than Erythromycin against Legionella pneumophila strains.
In addition, the active ingredient Clarithromycin also has the ability to fight Helicobacter pylori (HP), making it effective in the treatment of peptic ulcers. Not only that, Clarithromycin is also highly appreciated by experts for its very good effect against gram-positive, gram-negative, anaerobic and aerophilic bacteria, such as:
Group B hemolytic streptococcus (Streptococcus pyogenes) . Viridans group A hemolytic streptococci. Staphylococcus aureus strains. Streptococcus agalactiae strain. Listeria monocytogenes strain. strain Neisseria gonorrhoeae. Haemophilus influenzae strain. Macrolid-sensitive Bacteroides fragilis strain Propionibacterium acnes strain. Ureaplasma urealyticum strain. Besides, the active ingredient Clarithromycin also has strong activity against some other microorganisms such as Mycobacterium leprae, Chlamydia trachomatis, Mycobacterium chelonae, Mycobacterium Kansasii, Mycobacterium avium or Mycobacterium intracellulare.
2.2. Indications and contraindications of the drug Fonclar? Fonclar is used by doctor's prescription to treat the following infections:
Otitis media. Tonsillitis. Chronic bronchitis with exacerbations. Acute sinusitis. Skin or soft tissue infections. Pneumonia caused by Legionella or Mycoplasma pneumoniae. Diphtheria . Treatment of whooping cough early stage. Opportunistic infections caused by Mycobacterium. Combined with other drugs to destroy Hp strains in peptic ulcer disease. Treatment of community-acquired pneumonia. Treatment of infections caused by Mycobacterial intracellular or Mycobacterium avium. Prophylaxis of disseminated infection by MAC complex in persons with advanced HIV infection. However, it is necessary to avoid using Fonclar drug in the following cases of patients without a doctor's prescription:
Contraindicated Fonclar drug for people with a history of hypersensitivity or allergy to Clarithromycin, other antibiotics other macrolides, or any of the excipients. Fonclar should not be administered to patients taking Ergot derivatives. Fonclar is contraindicated in people taking any medications such as Pimozide, Terfenadine or Cisaprid. Fonclar is relatively contraindicated for pregnant women or nursing mothers.

Fonclar is used by doctor's prescription orally with the following general recommended dosage:
Dosage for adults and children > 12 years: Oral 250mg x 2 times / day, treatment within 1 week; or take 500mg of the extended-release form once a day. For patients with severe infections may consider increasing the dose up to 500 mg twice daily or 1000 mg as a once-daily release, for a duration of approximately 2 weeks. Dose for children < 12 years: Use the drug in the form of an emulsion. The daily therapeutic dose is 7.5mg/kg body weight x 2 times/day until the maximum dose is 500mg. The duration of using Fonclar medicine for children usually lasts from 7 to 10 days, depending on the strain of bacteria causing the disease as well as the severity of the infection. To treat strep throat in children of this age, it is necessary to take the drug for at least 10 days. Children can take the medicine with milk or with meals. Hp killing dose in duodenal ulcer disease: Adults should take a dose of 500mg x 2 times / day, used within 1 week. In addition, the drug should be combined with Omeprazole 40mg twice a day to increase the effectiveness of treatment. Dosage for patients with renal impairment: Dosage adjustment is required for patients with severe renal impairment (creatinine clearance < 30ml/min). Doctors may have patients reduce their total daily dose by half in cases of severe decreased kidney function. Patients need to apply the correct dose of Fonclar, avoid increasing or decreasing the dose without the approval of the doctor. In addition, patients also need to take the medicine at the prescribed time, absolutely do not prolong the treatment time because this easily leads to the development of drug-resistant bacteria.

Although the active ingredient Clarithromycin in Fonclar is well tolerated after oral administration, patients still have a risk of experiencing some adverse reactions during treatment, specifically:
Common side effects : Gryngitis, stomatitis, granulomatous in mouth, headache. Uncommon side effects: Allergic reactions (urticaria, mild skin rash or anaphylaxis), Stevens-Johnson syndrome, reversible tongue discoloration, taste disturbances, dizziness, insomnia, anxiety, hallucinations, reversible hearing loss, psychosis, confusion or nightmares. Rare side effects: Liver dysfunction, pseudomembranous colitis, hepatitis, cholangitis, jaundice, fatal liver failure. In addition to the above reactions, you may experience some other side effects that have not been mentioned. If you notice the appearance of any of these symptoms after taking Fonclar, you need to stop treatment and tell your doctor as soon as possible.

During the treatment of bacterial infections with Fonclar, you need to be cautious of a few things to use the drug effectively and safely:
The active ingredient Clarithromycin is excreted by the kidneys and liver, so care should be taken when taking it. medicine for people with impaired liver/kidney function. Do not use Fonclar for a long time or repeatedly to avoid the risk of developing bacteria or fungi that are no longer sensitive to the drug. Treatment should be discontinued immediately if superinfection occurs, and appropriate therapy instituted promptly. Risk of increased serum concentrations of drugs metabolised via the G450 cytochrome system when used in combination with clarithromycin. Use caution when using Fonclar for elderly patients, pregnant women, lactating women, children under 15 years of age, people with hypersensitivity to active ingredients in the drug, stomach ulcers, myasthenia gravis. or hepatic coma. Avoid taking Fonclar with other drugs such as Lovastatin, Disopyramide, Warfarin, Ergot alkaloids, Cyclosporin, Phenytoin, Triazolam, Theophylline, Klacid, Digoxin, Carbamazepine, Zidovudine, Maalox or Ranitidine. Ideally, you should tell your doctor about any medications you are currently taking, including supplements, vitamins, supplements, dietary supplements or herbs. Check the expiration date of Fonclar medicine to avoid taking expired medicine. Check the quality of the medicine, if the tablet shows signs of watery, discolored or deformed, you need to stop using it immediately. The basic information about the drug Fonclar in the above article is for reference only. Because Fonclar is a prescription drug, patients should not use it on their own, but need to contact a specialist directly to get an appropriate prescription to ensure safety for health.