Uses of Garbapia

"What is the use of Garbapia?". Garbapia medicine contains the active ingredient Gabapentin 300mg, which is made in capsule form. The active ingredient Gabapentin is structurally related to GABA - a neurotransmitter. The drug acts by mechanism of interaction with GABA synapses, partially reducing the response to Glutamate N - Methyl - D - Aspartate (NMDA) agonists, slightly reducing the release of the structural neurotransmitter. Monoamine structure in vitro.
Garbapia is indicated in the following cases:
Treatment of epilepsy:
Gabapentin is indicated as monotherapy in the treatment of partial seizures with or without secondary generalization in children, adults over 12 years old; Gabapentin is indicated as adjunctive therapy in the treatment of partial seizures with or without secondary generalization in adults and children over 3 years of age. The safety and effectiveness of the regimen when used in children under 3 years of age have not been established. Treatment of neuropathic pain: The drug is indicated in the treatment of neuropathic pain in patients over 18 years of age.

Garbapia drug belongs to the group of prescription drugs. The dose of the drug used is prescribed by the treating doctor based on the patient's condition. Some recommendations on Garbapia dosage are as follows:
In the treatment of epilepsy:
Adults and children over 12 years of age: The recommended starting dose is 300mg/time x 3 times/day on the first day, the dose of the drug is 300mg/time x 3 times/day. can then be increased to a maximum of 3600mg/day in 3 divided doses during the day. The interval between doses of the day for a three-time-daily regimen should not exceed 12 hours to avoid flare-ups; Children from 3 to 12 years old: The effective dose is 25-35mg/kg/day divided into 3 times. The first dose should be started at 10mg/kg/day on the first day, 20mg/kg/day on the second day, and 30mg/kg/day on the third day to find an effective maintenance dose for the patient. afterward; If gabapentin treatment must be discontinued or an alternative anticonvulsant is added, gabapentin treatment should be discontinued at least 1 week prior. In the treatment of neuropathic pain in adults:
The recommended starting dose is 900mg/day in 3 divided doses and increased as needed, to a maximum recommended dose of 3600mg/day. The dose of Garbapia in the treatment of epilepsy and neuropathic pain needs to be adjusted in patients with renal impairment. For patients on hemodialysis and who have never been treated with gabapentin, the recommended dose of Garbapia is 300-400mg initially, then the dose should be reduced to 200-300mg every 4 hours on dialysis. blood filtration.

Garbapia drug can cause some side effects as follows:
Systemic side effects: Weakness, weakness, facial edema; On the digestive system: Anorexia, flatulence, gingivitis; On the cardiovascular system: Hypertension; On blood and lymphatic system: Skin rash, bruising encountered with trauma; On the musculoskeletal system: Arthritis pain; Nervous system: Hyperactivity, dizziness, decreased or absent reflexes, anxiety, paresthesia, feelings of hatred; On the respiratory system: Pneumonia ; On the genitourinary system: Urinary tract infections; On the senses: Abnormal vision.

Contraindicated when using Garbapia in patients with hypersensitivity to Gabapentin or any of its ingredients.
Some cautions when using Garbapia drug are as follows:
Although there is no specific evidence of seizures with gabapentin, abrupt discontinuation of anticonvulsants in patients with epilepsy may cause seizures. ongoing seizures in the patient; Garbapia is generally not effective in the treatment of absence seizures; For pregnant women: There are no specific studies on the safety of using Garbapia in pregnant women. Therefore, the drug should only be used in this subject when absolutely necessary and under the supervision of medical staff; For lactating women: Gabapentin is excreted in breast milk, the effect of the drug on the nursing infant has not been specifically studied. Therefore, the use of the drug in lactating women should be prescribed by a doctor based on the benefits and risks.

Garbapia drug can cause some interactions as follows:
Concomitant use of Gabapentin and oral contraceptives containing Norethindrone, Ethinylestradiol does not affect the pharmacokinetics of both drugs in plasma; Gabapentin bioavailability is reduced by about 20% when used concurrently with magnesium salts, aluminum salts. Therefore, it is necessary to take Gabapentin at least 2 hours apart from the above drugs; Renal excretion of Gabapentin was slightly reduced when co-administered with cimetidine, but this reduction was not clinically significant; Urine protein test using Ames N - Multistix SG dipstick gave false positive results during Garbapia treatment. Drug interactions occur to reduce the therapeutic effect of Garbapia, increasing the risk of unwanted effects. Therefore, patients need to inform their doctors about the drugs and supplements they are using before being treated with Garbapia to ensure safety and effectiveness during treatment.
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