Uses of Glucofast 850

The main ingredient Glucofast is metformin, an oral hypoglycemic agent that is not related to sulfonylureas in chemical structure or mode of action. Metformin reduces fasting and postprandial plasma glucose concentrations in patients with type 2 diabetes. The mechanism of action of metformin is to inhibit glucose synthesis in the liver and reduce intestinal glucose absorption, increase glucose utilization in cells, improve insulin binding to receptors, and stimulate anaerobic glucose breakdown. gas. The drug also has no effect on lowering blood sugar in people without diabetes.
In addition to its anti-hyperglycemic effect, metformin also has a beneficial effect on the composition of blood lipids in patients with type 2 diabetes, reducing levels of triglycerides, total cholesterol and LDL cholesterol. Glucofast is commonly used to treat:
Type II diabetes, especially overweight subjects when diet and exercise alone are not effective in blood sugar control. Other oral antidiabetic agents or adult insulin In children from 10 years of age and adolescents: monotherapy or in combination with insulin Some contraindications to Glucofast include:
Patients with known hypersensitivity to metformin or other drugs. other components of the drug Patients with impaired renal function, renal dysfunction, or due to heart failure, acute myocardial infarction, sepsis Acute or chronic metabolic acidosis, with or without coma ( (including diabetic ketoacidosis) Severe liver disease, severe respiratory disease with hypoxia, cardiovascular collapse, congestive heart failure, acute myocardial infarction, severe infection, sepsis, or cases of death Acute metabolic compensation Pregnant women Necrosis, alcoholism, malnutrition

Depending on the subject and the treatment goal, the dose of Glucofast will be different, specifically as follows:
Starting dose:
1 tablet x 1 time/day taken at breakfast Increase dose by 1 tablet/ daily, 1 time per week increase, up to a maximum of 3 tablets/day Maintenance dose:
1 tablet x 2 times/day taken with breakfast and dinner Some patients may take 1 tablet x 3 times/ Days at meals Elderly people need to be careful when using Glucofast at the starting and maintenance dose, not up to the maximum dose of metformin. After 4 weeks of treatment at the maximum dose of metformin, if a response is not satisfactory, a sulfonylurea may be considered. treated with oral medication and started insulin.

In some patients when using Glucofast, side effects may occur such as:
Digestive disorders: anorexia, nausea, vomiting, constipation, epigastric pain Decrease vitamin B12 levels Lactic acidosis Lowering sugar Blood Anemia, thrombocytopenia, agranulocytosis

Some notes when using Glucofast include:
Regular laboratory tests, including blood glucose measurements, are required to determine the minimum effective dose of metformin. Informing patients about the risk of lactic acidosis and the circumstances that predispose it to this condition. Metformin should only be considered an adjunct, not a substitute. Metformin is mainly excreted by the kidney, the risk of accumulation and lactic acidosis increases with the degree of renal function decline with caution when administering metformin to the elderly, excessive exercise When changing therapy from clopropamide to metformin Care should be taken in the first 2 weeks, because the prolonged retention of clopropamide in the body can lead to drug interactions and hypoglycemia. Metformin therapy should be discontinued 2-3 days before X-ray. - X-ray using iodinated contrast and only reinstated when normal renal function is assessed. Discontinue metformin during surgery

Glucofast drugs reduce the effect when used with drugs that tend to cause hyperglycemia (diuretics, corticosteroids, phenothiazines, oral contraceptives, thyroid preparations, calcium channel blockers, isoniazid) Furosemide increases the concentration. Maximize plasma and blood metformin without altering the renal clearance of metformin in a single dose study Metformin toxicity is increased when co-administered with cationic drugs and cimetidine, because of increased peak concentrations. of metformin in plasma and whole blood. Glucofast 850 belongs to the biguanides group of drugs with the main ingredient being metformin, indicated in the treatment of type 2 diabetes in patients who are not well controlled by diet and exercise. Patients need to strictly follow the instructions to achieve the highest treatment effect and avoid side effects.
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