Uses of medicine Fordia

Fordia medicine 500mg has the main active ingredient is Metformin with the content of 500mg and other excipients in sufficient quantity. This is a hormone drug, often prescribed by doctors to treat type 2 diabetes or non-insulin dependent diabetes when daily diet and exercise do not control blood sugar. .

Fordia medicine 500mg has the main active ingredient is Metformin with the content of 500mg and other excipients in sufficient quantity. This is a hormone drug, often prescribed by doctors to treat type 2 diabetes or non-insulin dependent diabetes when daily diet and exercise do not control blood sugar. .
Fordia 500mg drug is made in the form of tablets, suitable for direct oral use. Packing is a medicine box of 25 blisters, each blister contains 4 pills or a medicine box includes 1 blister, each blister contains 4 pills.
1.1. Pharmacodynamics of active ingredient Metformin Main active ingredient Metformin, also known as Metformin hydrochloride (Metformin HCl) is an oral biguanide for the treatment of type 2 diabetes. This active ingredient is effective in improving sugar tolerance in people with type 2 diabetes and lowering blood sugar levels at normal and after meals. Metformin HCl reduces hepatic glucose production and improves insulin sensitivity by increasing peripheral glucose uptake and consumption. Metformin HCl has beneficial effects on serum lipid composition in subjects with type 2 diabetes. The active substance Metformin HCl also reduces mean fasting serum concentrations of triglycerides, total cholesterol, and cholesterol. low density without adverse effects on other lipid concentrations. Increased fibrinolytic activity and decreased platelet aggregation have been observed in subjects with diabetes mellitus following treatment with the active ingredient Metformin HCl. 1.2. Pharmacokinetics of the active substance Metformin Absorption: The bioavailability of the active substance Metformin HCl is about 50 - 60% when administered on an empty stomach. Food reduces the amount of absorption and does not significantly slow down the rate of absorption of the active substance Metformin HCl. Distribution: This active substance is sparingly bound to plasma proteins. It is likely that over time, the drug will disperse into the red blood cells. Steady state plasma concentrations are reached after 24 to 48 hours and are usually < 1 mcg/mL. Metabolism and Elimination: After oral administration, approximately 90% of the absorbed active substance Metformin HCl will be eliminated by the kidneys within the first 24 hours. The mean half-life of Metformin HCl is 6.2 hours.

What is the effect of the drug Fordia? Fordia 500mg is indicated for use in the following cases:
Treatment of type 2 diabetes in adults, especially in overweight people, when diet and exercise are not controlled. blood sugar control. Fordia 500mg can be used alone or in combination with other oral antidiabetic agents, or with insulin.

3.1. How to use Fordia 500mg: Fordia 500mg is prepared in the form of tablets suitable for oral use. Dosage: Dosage of Metformin HCl is individualized based on efficacy and tolerability but should not exceed 2550 mg per day. Initial dose: Take 500mg each time, 2 times a day, use in the morning and evening. In case of necessity, the therapeutic dose can be increased by one 500mg tablet per day, 1 time per week, should be divided into several times a day, up to a maximum of 2000 mg/day. Maintenance dose: Take 500mg, use 2 to 3 times a day, take with meals. It is recommended to divide the dose of Metformin HCl used several times with meals and start with a low therapeutic dose, increase the dose gradually to reduce unwanted effects on the digestive system as well as easily determine the dose. Use the minimum necessary to control the amount of sugar that is appropriate for a particular person. It should be noted: The therapeutic dose as provided above is for reference only. The specific treatment dose depends on the health condition and severity of the disease for each person. For a specific and appropriate dose, you need to consult your treating doctor or medical professionals.
3.2. Overdose/Forgotten Dosage Case of Overdose: No reduction in blood sugar was observed after taking 85g of the active ingredient Metformin HCl, although lactic acidosis did occur in that case. Metformin HCl is dialyzable with a clearance of up to 170 ml/min; hemodialysis may therefore have a cumulative effect of eliminating the drug in those suspected of having an overdose. Missed dose: If you miss a dose, you should try to take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note that you should not double the prescribed therapeutic dose.

During the use of Fordia 500mg medicine, you may experience unwanted effects, specifically as follows.
Diarrhea, lactic acidosis, loss of appetite, abdominal pain, nausea and metallic taste in the tongue. Decreased ability to absorb vitamin B12 and folic acid from the digestive system caused by long-term treatment with active ingredient Metformin HCl. Some cases of megaloblastic anemia have been reported while using drugs containing the active ingredient Metformin HCl. Instructions on how to handle unwanted effects of Fordia 500mg: When experiencing side effects of the drug, the patient should stop using and notify the treating doctor or go to the nearest medical facility for proper treatment. manner and in a timely manner.

Drugs for the treatment of diabetes: Acarbose reduces the bioavailability of the active substance Metformin HCl. Diuretics: Thiazide diuretics may aggravate the condition, increase the need for oral antidiabetic agents, and temporarily lose or not control diabetes. response to antidiabetic drugs. Concomitant use of the diuretics Furosemide and Metformin HCl increases peak plasma and blood concentrations of the active substance Metformin HCl. Concomitant use of Nifedipine with Fordia in healthy people increases the absorption and excretion of the active substance Metformin HCl in the urine. Drugs that are renally eliminated (eg, Amiloride, Digoxin, Morphine, Procainamide, Quinidine, Quinine, Ranitidine, Triamterene, Trimethoprim, Vancomycin): May increase peak plasma concentrations, whole blood concentrations, and plasma concentrations. Whole blood AUC of active substance Metformin HCl. Beta-adrenergic blocking agents may decrease glucose tolerance, increase frequency and severity of hypoglycemia, and inhibit tachycardia and increased sweating with hypoglycemia. , slows down the rate at which blood sugar levels recover after a drug-induced drop in blood sugar; alter the hemodynamic response to impaired peripheral circulation. Alcohol: The combination of alcohol and drugs containing the active ingredient Metformin HCl, specifically Fordia increases the risk of hypoglycemia and lactic acidosis. Angiotensin-converting enzyme (ACE) inhibitors reduce fasting blood sugar levels in people without diabetes and increase insulin sensitivity. In addition, drugs that raise blood glucose and may adversely affect blood sugar control for people with diabetes include corticosteroids, oral contraceptives, sympathomimetic drugs, Phenothiazine, Niacin, calcium channel blockers and Isoniazid.

Before using Fordia you need to carefully read the instructions for use and refer to the information below.
6.1. Contraindications of Fordia drug Fordia 500mg drug is contraindicated in the following cases:
Specific acute catabolic states such as severe infection, sepsis, trauma. Patients with renal disease or renal dysfunction or abnormal creatinine clearance which may also result from cardiovascular collapse (shock) or acute myocardial infarction and sepsis. People with sensitive or hypersensitivity to the active ingredient Metformin HCl or other ingredients. Patients with acute or chronic metabolic acidosis, with or without coma, including diabetic ketoacidosis. People with liver failure, severe respiratory disease with reduced oxygen levels in the blood. Congestive heart failure, cardiovascular collapse, acute myocardial infarction. Cases of acute metabolic decompensation such as infection or gangrene. Women who are pregnant. Before X-ray, there is an injection of contrast material including iodine component. People with alcoholism, malnutrition. 6.2. Caution when using Fordia drug Caution when using Fordia drug in the following cases:
Regular monitoring of laboratory tests, including blood sugar, is necessary to determine the maximum therapeutic dose of the active substance Metformin HCl. minimum in effect. You need to be informed about the risk of lactic acidosis and the circumstances that predispose to it. Fordia users should be advised to regulate their diet properly. Treatment with the active ingredient Metformin HCl should be combined with proper dietary regulation. Metformin HCl is excreted mainly by the kidneys. The risk of drug accumulation and lactic acidosis increases with the degree of renal impairment. The doctor will order a serum creatinine test before starting treatment for the elderly. Treatment with drugs containing the active ingredient Metformin HCl must be discontinued 2 to 3 days before X-rays using iodinated contrast, and for 2 days after the scan. You re-administer metformin HCl after renal function reassess is found to be normal. Caution should be exercised when co-administering with drugs that affect renal function, or alter hemodynamics, or affect the distribution of metformin HCl. Fordia must be discontinued during surgery. Do not use Fordia for people with impaired liver function. Ability to drive and use machines: The use of Metformin monotherapy does not cause hypoglycemia, so it does not affect the ability to drive and use machines. However, you should be warned about the risk of hypoglycaemia with concomitant treatment with Metformin-containing medicines and other antidiabetic agents (sulfonylureas, insulin, repaglinide). Metformin may cause headache and dizziness in very rare cases and therefore the ability to drive or use machines may be impaired. Pregnancy: There are currently no adequate and well-controlled studies performed in humans. Fordia should not be used during pregnancy unless clearly needed. Lactation: Studies in rats have shown that the active substance Metformin HCl is excreted in milk. Because of the potential for hypoglycaemia in the nursing infant, consideration should be given to discontinuing Fordia or stopping breastfeeding, given the importance of the drug to the health of the mother. Above is all information about Fordia medicine, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Fordia drugs to treat diseases at home, because there may be unwanted side effects on health.
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