Uses of Nafelof Tablet

Nafelof Tablet is used to prevent and slow down cholesterol metabolism, reduce total cholesterol and bad blood fats; prevent mixed dyslipidemia. When there is excess cholesterol, the probability of accumulation of cholesterol and lipids in the walls of blood vessels can create cardiovascular disorders such as heart attack, stroke, atherosclerosis,...

Nafelof Tablet is a prescription drug specializing in the treatment of primary hypercholesterolemia, manufactured in the form of film-coated tablets, packaged in blisters. There are 2 types of packaging: box of 3 blisters and box of 5 blisters, each blister of 10 tablets. The main active ingredient in Nafelof Tablet is Rosuvastatin, extracted in the form of Rosuvastatin calcium 10 mg, this is a group of statin drugs that help reduce bad cholesterol and increase good cholesterol in the blood. This drug also helps to slow the progression of cardiovascular diseases such as atherosclerosis, coronary heart disease, ... Besides, it also helps to treat to prevent the risk of cardiovascular events such as myocardial infarction. heart attack, shock, stroke.

The drug Nafelof Tablet includes the active ingredient Rosuvastatin and other excipients. The effect of this drug in the drug helps to reduce the production of bad cholesterol (LDL) in the blood, increase the concentration of good cholesterol (HDL), change blood lipids, reduce bad fats and triglycerides. Specifically:
When entering the body, Rosuvastatin is converted into Hydroxy Acid with the property, inhibiting the enzyme HMG - CoA, which has the effect of metabolizing cholesterol in the liver, thereby reducing cholesterol produced in this organ. Helps reduce cholesterol in the liver, specifically LDL - C in the liver (a type of low molecular weight cholesterol), Apolipoprotein B (ApoB) and bad cholesterol Triglycerides. For patients with hyperlipidemia or mixed dyslipidemia, Nafelof Tablet helps increase good cholesterol - high molecular weight cholesterol (HDL-C). Helps reduce blood triglyceride levels in patients with hypertriglyceridemia. Helps reduce triglyceride and very low molecular weight cholesterol (VLDL-C) levels in patients with primary dyslipidemia. Nafelof Tablet is indicated for use in the following cases:
Treatment of primary hyperlipidemia: when the cholesterol index, ApoB index, blood lipid tri, and low-molecular-weight lipoprotein cholesterol in the blood are recorded in high level. Treatment of high levels of bad fats and triglycerides in the blood Treatment of primary dyslipidemia Treatment for adults and children 7 to 17 years of age with homozygous familial hypercholesterolemia Treatment for children 8 to 17 years of age heterozygous familial hypercholesterolemia Slows progression of atherosclerosis in patients with this condition Prevents primary cardiovascular disease

3.1. How to use Nafelof Tablet For the drug Nafelof Tablet, patients are required to follow a diet to reduce cholesterol during the process before and during treatment. Depending on the treatment goals and the patient's response to medication, the dose of Nafelof Tablet will be different and customized.
Patients are required to use Nafelof Tablet according to the dose prescribed by the doctor. Take the medicine every day for the full effect of the medicine.
If you forget to take your medicine, take it as soon as you remember for the day. However, if it is almost time for your next dose, use Nafelof Tablet as prescribed by your doctor, do not double the dose, to avoid an overdose.
3.2. Dosage of Nafelof Tablet For adult patients: Consider using a starting dose of 10 mg a day, then monitor the body's absorption of the drug, whether unwanted symptoms occur or not, and disease progression and gradually increased to a maximum dose of 40 mg/day.
For pediatric patients: The recommended dose for this population is from 5 to 50 mg per day. The maximum tolerable dose is 20 mg/day, and dose adjustments for severe disease should only be made after an interval of 4 weeks or more.
3.3. Contraindications to the drug Nafelof Tablet Contraindicated to use Nafelof Tablet with hypersensitivity, allergy to any ingredient of the drug. Contraindicated in patients with severe renal impairment and reduced renal function. The use of Nafelof Tablet is contraindicated in patients with a history of or active liver disease or elevation of blood transaminases more than 3 times the allowable limit.

4.1 Nafelof Tablet side effects When using Nafelof Tablet, patients may experience unwanted side effects such as:
Common reactions: muscle pain, constipation, fatigue, abdominal pain and nausea Yes may experience disorders of the endocrine, nervous, and digestive systems such as headache, dizziness, nausea, muscle atrophy, myositis, weakness,... Uncommon effects include allergic reactions such as itching. snoring, rash, urticaria Need to immediately inform the treating doctor about the unwanted effects encountered when using the drug.
4.2 Nafelof Tablet Drug Interactions When Nafelof Tablet is co-administered with strong CYP3A4 inhibitors, clinical studies have shown that the clearance of Rosuvastatin is independent of this drug.
Rosuvastatin drug belongs to the Statin group, so there is an interaction with Cyclosporin, Erythromycin, Gemfibrozil.
Concomitant use with aluminum-based antacids and magnesium hydroxide can reduce blood concentrations of Rosuvastatin by about 50%.
There is a very high risk of myopathy and rhabdomyolysis when Nafelof Tablet is used together with HIV and hepatitis C protease inhibitors. Due to the increased effect of Rosuvastatin, high concentrations are produced. in plasma, causing rhabdomyolysis, kidney failure; lead to kidney failure and death. Limit dose and use caution when used concurrently.
4.3 Store Nafelof Tablet Store Nafelof Tablet in a cool, dry place Store the medicine at a temperature from below 30 degrees Celsius, do not let sunlight shine on the product Keep the medicine in a place out of reach Children and pets This is the complete information about Nafelof Tablet. This is a drug that requires a doctor's prescription. Follow the prescribed dose and carefully read the instructions for use before use.