Uses of Rocimus 0.1

Manufacturer: The Madras Pharmaceuticals - India.
Packing: Each box contains 1 tube of 10g.
Dosage form: Skin ointment.
Ingredients: Each 10g tube has ingredients:
Tacrolimus 0.1%. Excipients (Parafin, beeswax, Propylene Carbonate,...) just enough for 1 tube of 10g.

Effects of Tacrolimus:
Tacrolimus is a substance that inhibits T lymphocytes by binding to intracellular proteins. From there, forming complexes that prevent dephosphorylation and prevent the translocation of NF-AT (the component that initiates the transcription of genes for Lymphokines synthesis). In addition, Tacrolimus helps prevent the release of inflammatory mediators.
Indications:
The drug is used in the following cases:
Atopic dermatitis. Hand eczema, eyelid dermatitis, steroid hypersensitivity erythema, pyoderma, graft rejection. Dosage - How to use
How to use:
The drug is used by topical application. Wash the affected skin area and apply the medicine evenly, then wash your hands. Do not apply the medicine to the eyes or mucous membranes. If it gets in contact, wash it off immediately with clean water. Dosage:
Use the drug as prescribed by the doctor or you can refer to the following dose:
Apply twice a day, just apply a thin layer of medicine to the skin. Usually used once a week or until symptoms are gone. Missed dose, overdose and management
Missed dose : Reapply as soon as you remember as soon as possible. If it is almost time for the next dose, skip the missed dose and continue as scheduled.
Overdose : There have been no reports of an overdose of topical ointments. If accidentally applied to the eyes or swallowed, supportive treatment should be instituted.

Possible side effects are as follows:
Very common : Hot, itchy at the application site.
Common:
+ Erythema, irritation, rash at the site of application.
+ Folliculitis, itching.
+ Paresthesia, increased sensation.
+ Blushing after drinking alcoholic beverages.
Rare : Acne .
If you experience any of the above abnormalities, call the doctor or take the patient to the nearest medical center for appropriate treatment.

Contraindications:
Rocimus 0.1% should not be used for the following subjects:
People with a history of allergy to any ingredient of the drug. Hypersensitivity to macrolides. Use for pregnant women and lactating mothers:
For pregnant women: The drug crosses the placental barrier and safety has not yet been established for this population. Therefore, caution should be exercised during pregnancy. Consult your doctor before use.
For nursing mothers : The drug may be excreted in breast milk. Should only be used when the potential benefits outweigh the possible risks. Consult your doctor before use.
People who drive and operate machinery
It is not known whether the drug is safe for driving and operating machinery. Care should be taken when using.
Other note:
Only use the medicine according to the doctor's prescription. The safety of use in children under 2 years of age is unknown. Limit skin exposure to sunlight, wear sunscreen or wear tight clothing. It is necessary to treat the infection at the site of the lesion before administering the drug. Sealing after application is not recommended. Safety for use in people with systemic erythema has not been established. If accidentally applied to the eyes or mucous membranes, it should be wiped clean and rinsed with water. Use with caution in patients with hepatic impairment.

No interaction of Rocimus 0.1% with other drugs has been found. Due to the risk of vaccination, vaccination should be given prior to administration or during discontinuation with a 14-day interval. If using live attenuated vaccines, the interval should be up to 28 days or replace with another vaccine.
In order to prevent drug interactions, patients should report all topical medications they are taking to their doctor for advice on the most appropriate use.

Store below 30 degrees Celsius. Tighten cap after each use. Keep in a dry place, avoid direct sunlight. Keep out of reach of children.