Uses of Sintasone

Sintasone is an anti-allergic drug commonly prescribed in severe allergic diseases caused by pollen, drugs, urticaria, atopic dermatitis, ... So its use and notes when using the drug what?

Sintasone has ingredients including Betamethasone and Dexchlorpheniramine maleate.
Ingredients Dexchlorpheniramine maleate - is an antihistamine that inhibits H1 receptors. In an allergic reaction, when a foreign antigen appears in the body, it will trigger a series of reactions that release histamine and other chemical mediators. Histamine causes inflammation, itching, vasodilation, hypotension, tachycardia, bronchospasm,... Dexchlorpheniramine competes with histamine and reduces allergic reactions.
Ingredients Betamethasone - is a form of steroid with anti-inflammatory effects, high doses cause immunosuppression. The drug works to suppress inflammatory reactions in the body by inhibiting inflammatory factors.
The combination of both ingredients in Sintasone increases the anti-inflammatory effect, treating severe allergic symptoms caused by many causes.

Sintasone is indicated for the treatment of the following pathologies
Urticaria, eczema, atopic dermatitis, contact dermatitis. Severe allergies due to pollen, drug, and airborne allergens. Acute exacerbation of chronic bronchial asthma with allergic triggers. Allergic conjunctivitis.

Sintasone drug is not contraindicated in patients
Allergy to Betamethasone, Dexchlorpheniramine maleate or any other ingredient of the drug. Patients with diabetes mellitus. Patients with unstable neuropsychiatric diseases. Active peptic ulcer, or history of bleeding from a peptic ulcer. Patients with existing bacterial, viral, or systemic fungal infections who take Sintasone may experience increased symptoms of infection. Note when using Sintasone
In case patients have infectious diseases, severe stress, after trauma, surgery can change the concentration of Sintasone in plasma, so it is necessary to adjust the dose appropriately. . Betamethasone component in the drug can mask infection symptoms, make new infections appear, reduce local resistance. Sintasone should be used with caution in patients with angle-closure glaucoma, narrow gastric ulcer, prostatic hypertrophy, pyloric obstruction, bladder neck or cardiovascular disease. There is no evidence of safety for children under 2 years of age, so the drug should not be used in this population. Pregnant women taking Sintasone may have an increased risk of adrenal insufficiency in the fetus. Antihistamines in the drug cause somnolence, drowsiness, and hypotension in the elderly.

Co-administration of Sintasone with salicylates increases the risk of salicylate toxicity. Anticoagulants, oral antidiabetic drugs are reduced when used together with Sintasone. Barbiturates, rifampicin, carbamazepine, phenobarbital,... increase the metabolism of Sintasone, thereby reducing its effectiveness. Concomitant use of acetazolamide, carbenoxolone with Sintasone increases the hypokalemic effect of the drug. Antihypertensive drugs, diuretics are reduced when used together with Sintasone.

How to use
Sintasone is made in the form of tablets, taken whole with water, avoid crushing or breaking the medicine. Take medicine after eating.
Dosage
Adults and children over 15 years old: take 1-2 tablets/time x 3-4 times/day. Children from 8 to 14 years old: take 1⁄2 - 1 tablet/time x 3-4 times/day. Children from 3 to 7 years old: take 1⁄4-1⁄2 tablets/time x 2-3 times/day.

Some unwanted effects may be encountered when using Sintasone
Allergic reactions. Psychosis, agitation, anxiety, restlessness. Peptic ulcer. Frequent urination, difficulty urinating. Hypertension. Leukocytosis, thrombocytopenia, thrombocytopenia. Irregular menstruation. Osteoporosis . Glaucoma, cataracts. Weight gain. Infections, fungal infections. As such, Sintasone is an antiallergic drug that must be prescribed by a doctor before use. The drug is highly effective in treating severe allergic diseases by many different allergens, but it also causes many unwanted effects on the body. Therefore, it is important to use it exactly as directed by the doctor in terms of dosage and duration.