Uses of the drug Rotinvast 10

Rotinvast 10 has the active ingredient Rosuvastatin 10mg. This is a drug indicated in the treatment of hypercholesterolemia, effectively improving dyslipidemia.

Rotinvast 10 has the active ingredient Rosuvastatin 10mg. This is a drug indicated in the treatment of hypercholesterolemia, effectively improving dyslipidemia.
Rotinvast 10 is formulated in the form of film-coated tablets, suitable for direct oral use.

Rotinvast 10 is indicated for use in the following cases:
Treatment of primary hypercholesterolemia (type lIa including heterozygous familial hypercholesterolaemia) or mixed dyslipidemia (type 1lb). ). Treatment of primary hypercholesterolemia (type Ia), mixed dyslipidemia (type Ilb), hypertriglyceridemia (type IV). Treatment of heterozygous familial hypercholesterolemia in male or female adolescents (at least 1 year after the first menstrual period) aged 10 to 17 years. Treatment of homozygous familial hypercholesterolemia. Slow down the progression of atherosclerosis: Adjunct to daily diet to reduce total cholesterol and LDL-cholesterol to desired limits.

3.1. How to take the drug Rotinvast 10 Rotinvast medicine is made in the form of film-coated tablets, suitable for direct oral use and once a day. You should take the drug Rotinvast 10 at the same time every day, can be taken before, during or after meals because the absorption of the drug is not affected by food. However, because cholesterol synthesis in the liver occurs mainly at night, it is recommended that you take the drug at night to increase its effectiveness. You need to follow a standard, low cholesterol diet before taking Rotinvast 10 and must continue to maintain this diet throughout the treatment period. 3.2. Dosage of Rotinvast 10 The recommended starting dose is 5 mg or 10 mg once daily, increased every 4 weeks, if necessary, to 20 mg once daily. The treatment dose and duration of use of Rotinvast 10 depends on your medical condition. You need to be careful to use the medicine exactly as your doctor recommends. Rotinvast 10 should not be taken in more or less quantities or for a longer time than the therapeutic dose prescribed by the treating doctor. For the elderly: the starting dose of 5mg is used for people over 70 years old. No dose adjustment is required for this group of subjects. For patients with renal impairment: No dose adjustment is required for patients with mild to moderate renal impairment. Patients with moderate renal impairment with creatinine clearance < 60 ml/min are advised to start with 5 mg, but 40 mg is contraindicated. The use of drugs containing the active ingredient Rosuvastatin is contraindicated in people with severe renal impairment. Note that the above dose is for reference only and does not replace the doctor's treatment dose. The specific treatment dose depends on the medical condition and severity of the disease for each individual person. For a specific and appropriate therapeutic dose, you need to consult your treating doctor before using this medicine.

Adverse reactions or undesirable reactions reported with the use of Rotinvast 10 are usually mild and transient. The frequency of specific adverse reactions is as follows:
Undesirable effects of the drug Rotinvast 10 are common:
Nervous system disorders: Headache, dizziness and dizziness. Digestive system disorders: Constipation, nausea, abdominal pain. Musculoskeletal, connective tissue and bone disorders: Muscle pain. General disorders: Asthenia Undesirable effects of the drug Rotinvast 10, uncommon:
Skin and subcutaneous tissue disorders: Itching, rash and urticaria on the skin. Undesirable effects of the drug Rotinvast 10, rare:
Immune system disorders: Hypersensitivity reactions including angioedema. Musculoskeletal, connective tissue and bone disorders: Myopathy, rhabdomyolysis. Similar to other HMG-CoA reductase inhibitors, the frequency of adverse reactions tends to be dose dependent. You need to actively inform the treating doctor of any unwanted effects encountered during the use of Rotinvast 10.

Interactions of the drug Rotinvast 10 occur during use as follows:
Concurrent use of Cyclosporin with the drug Rotinvast 10 increases unwanted effects of active ingredient Rosuvastatin. The active ingredient Rosuvastatin increases the effects of the blood thinner Warfarin, increasing the risk of bleeding. Antacids reduce the absorption of active ingredient Rosuvastatin, should be used 2 hours after treatment with active ingredient Rosuvastatin. Concomitant use of Rotinvast 10 with Nicotinic acid, Gemfibrozil (Lopid) or other drugs may cause liver or muscle damage, increasing the incidence of muscle injuries. There is an increased risk of muscle damage when Rotinvast 10 is used concomitantly with the following drugs: Gemfibrozil, other fibrate-lowering agents, high-dose niacin (>1 g/day) or colchicine. Concomitant use of statin lipid-lowering drugs, specifically Rotinvast 10, with drugs for HIV and hepatitis C virus (HCV) may increase the risk of muscle damage, the most serious of which is diarrhea. Rhabdomyolysis, kidney failure leads to kidney failure and can be fatal.

6.1. Contraindications of the drug Rotinvast 10 Rotinvast drug is contraindicated for use in the following cases:
People with hypersensitivity or hypersensitivity to the main active ingredient Rosuvastatin or any excipients of the drug People with liver disease Unexplained persistent elevation of serum transaminase activity or activity. Patients with severe renal impairment with creatinine clearance < 30m ml/min. People with muscle disease. For women who are pregnant or breastfeeding, it is possible for women to become pregnant without using appropriate contraception. A therapeutic dose of ≥ 40 mg is contraindicated in the following subjects: Asians, patients with moderate renal impairment with creatinine clearance < 60 ml/min, people taking cyclosporin or other cholesterol-lowering agents. fibrates and people with predisposing factors for myopathy. 6.2. Note when using Rotinvast 10 You need to actively inform your doctor about signs or symptoms of muscle pain, fatigue, fever, dark urine, nausea or vomiting during use. drug Rotinvast 10 . Effects on skeletal muscle: Similar to other HMG-CoA reductase inhibitors, skeletal muscle effects such as inducing myalgia and myopathy are uncomplicated. Use caution when using Rotinvast 10 for people who are over 65 years old, people with hypothyroidism, kidney failure, a personal or family history of hereditary musculoskeletal diseases, people who are using drugs anti freeze blood . The treating doctor will order to measure the level of Creatine Kinase (CK) before taking the drug containing the active ingredient Rosuvastatin, do not use Rotinvast 10 if the CK level is high. Dose adjustment is required for Asians. Gemfibrozil increases the risk of myopathy when used concomitantly with certain HMG-CoA reductase inhibitors. Therefore, the combination of drugs containing the active ingredients Rosuvastatin and Gemfibrozil is not recommended. The combined use of Rotinvast 10 with Fibrates or Niacin to achieve further changes in lipid levels should be carefully weighed by the clinician between the potential benefits and risks for users of the drug due to these results. this case. The concomitant use of drugs containing the active ingredient Rosuvastatin, in particular Rotinvast 10, should not be used concurrently with patients with acute severe conditions, suspected myopathy, or which may lead to the development of secondary renal failure. due to rhabdomyolysis (such as sepsis, hypotension, major surgery, trauma, electrolyte disturbances, severe endocrine and metabolic health problems; or uncontrolled seizures). Effects on ability to drive or use machines: There is no information available on the effect of Rotinvast 10 on the ability to drive and use machines. However, you need to be aware of the undesirable effects of specific drugs such as headache, dizziness, blurred vision that may occur, affecting the ability to perform tasks that require high concentration. Effects of the drug Rotinvast 10 on pregnancy: Active ingredient Rosuvastatin is contraindicated in pregnant women. Women who may become pregnant should use appropriate contraception while taking the drug. The potential risks of HMG-CoA reductase inhibition outweigh the benefits of treatment with Rosuvastatin during pregnancy. Studies performed in animals have shown limited evidence of toxicity to the reproductive system. If you find out that you are pregnant during treatment with Rotinvast 10, you should stop taking it immediately. Effects of the drug on lactation: Contraindicated to use Rotinvast 10 with breast-feeding women. This is because statin drugs can pass into breast milk and HMG-CoA reductase inhibitors have the potential to cause serious adverse reactions in nursing infants. Breastfeeding mothers should not use this medicine. Above is all information about the drug Rotinvast 10, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Rotinvast 10 to treat diseases at home, because there may be unwanted side effects on health.
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