Uses of Tidacotrim

Tidacotrim drug is an antibiotic drug, the drug is made in the form of a capsule with the main ingredient in each tablet is:
Sulfamethoxazol 400mg Trimethoprim 80mg Sulfamethoxazol is a sulphonamide in combination with trimethoprim which is a synthetic lead antibiotic pyrimidine production. These two active ingredients are usually combined in a ratio of 1 trimethoprim and 5 sulfamethoxazole. This combination has created a synergistic effect that increases the effectiveness of treatment and reduces drug resistance. Sulfamethoxazole is structurally similar to para aminobenzoic acid (PABA). This active ingredient competes with PABA thanks to its high affinity for dihydropteroate synthetase, so it has the effect of inhibiting the phase I of folic acid synthesis of bacteria. Sulfamethoxazole has a broad antibacterial spectrum, it is active against many gram-negative and gram-positive aerobic bacteria including: Staphylococcus, Legionella pneumophila, Streptococcus, Salmonella, Shigella, Neisseria gonorrhoeae, Neisseria meningitidis, E. coli, Enterobacter , Klebsiella, Proteus mirabilis, Proteus indol positive, Haemophilus influenzae,.. Sulfamethoxazol resistant bacteria are: Enterococcus, Campylobacter and anaerobic bacteria. Trimethoprim is an antibiotic with bacteriostatic effect, it inhibits the enzyme dihydrofolate - reductase of bacteria. Trimethoprim is active against pathogens causing urinary tract infections such as E. coli, Klebsiella, Enterobacter, Proteus, Staphylococcus saprophyticus, Streptococcus faecalis and many types of coliform bacteria.

2.1. Indications Tidacotrim is used in the treatment of Gram (-), Gram (+) bacterial infections, especially for gonococcal infections, uncomplicated acute urinary tract infections and patients with Pneumocystis carinii pneumonia. In addition, Tidacotrim is also indicated in the following cases:
Infections caused by bacteria sensitive to sulfamethoxazole and trimethoprim antibiotics. Urinary tract infections. Prostatitis due to bacterial infection. Respiratory tract infections. Acute exacerbation of chronic bronchitis. Acute sinusitis in adults. Bacillary dysentery. 2.2. Contraindications Tidacotrim is contraindicated in the following cases:
People with hypersensitivity to any ingredient of the drug. Significant damage to liver parenchyma Severe renal failure Pregnant women. Pay attention to precautions when using Tidacotrim in the following cases:
Hematological disorders. Elderly women Lactating women G6PD deficient people Folate deficiency Mild and moderate renal failure.

Tidacotrim is used orally, patients need to take the drug with a sufficient amount of water. The dose of Tidacotrim should be according to the doctor's prescription. Reference dose of Tidacotrim for adults in specific cases is as follows:
Urinary tract infections: Use dose 1-2 tablets/time, twice daily, for 10 days of continuous treatment. Respiratory tract infections: Use dose 1-2 tablets/time, 2-3 times a day, continuous treatment for 10 days. Gastrointestinal infections (bacilli dysentery): Use dose 1-2 tablets/time, 2 times a day, continuous treatment for 5 days.

During the use of Tidacotrim, you may encounter some side effects of the drug, including:
Gastrointestinal disorders Inflammation of the mouth Skin reactions Tinnitus Erythema multiforme Stevens-Johnson syndrome Lyell syndrome Leukopenia, neutropenia, thrombocytopenia. If in the process of using the drug, the patient encounters any side effects of Tidacotrim, it is necessary to immediately notify the doctor or go to the nearest medical facility for timely treatment.

Tidacotrim may interact when used with the following drugs:
Thiazide diuretics. Warfarin. Phenytoin. Methotrexate . Pyrimethamine Blood sugar lowering drug. Cyclosporin . Indomethacin. To avoid drug interactions, patients need to inform their doctors about the drugs, herbs, and supplements they are using so that the doctor can evaluate and adjust accordingly.
Tidacotrim is a medication that is an antibiotic prescribed for use in the treatment of certain bacterial infections. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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