What does Zaclid do?

The drug Zaclid has the main ingredient is Esomeprazole 20mg, is made in the form of hard capsules containing enteric coated microparticles. Esomeprazole is a proton pump inhibitor drug, commonly used in the treatment of peptic ulcer disease and diseases such as gastroesophageal reflux disease.

Zaclid is a prescription medication that reduces gastric acid secretion by inhibiting the enzyme H+/K+ ATPase. Esomeprazole is indicated in the treatment of the following conditions:

● When you have gastroesophageal reflux disease (GERD) with signs of nausea, heartburn, belching and coughing, sore throat, feeling of pain. chest area.
Peptic ulcer disease - duodenum.
● When the body is infected with Helicobacter pylori causing peptic ulcer, it should be used to treat and prevent the risk of recurrence.
● Preventing side effects of non-steroidal anti-inflammatory drugs causing peptic ulcers.
Zollinger-Ellison syndrome.

Allergy to esomeprazole and to its components, including the benzimidazole subclass. Do not combine esomeprazole with atazanavir at the same time.

Dosage: Should be taken on an empty stomach, 1 hour before meals. Swallow the tablet whole, do not chew or crush the microparticles.
Dosage: Adults and children ≥12 years old:
When belching symptoms due to gastroesophageal reflux: 20mg, once a day x 4-8 weeks. With erosive reflux esophagitis: 40mg, once a day for 4 weeks. Further treatment is recommended if symptoms persist.
Stomach - duodenal ulcer: 20-40mg / 1 time / day for 4-8 weeks.
Prevention and treatment of peptic ulcers caused by non-steroidal anti-inflammatory drugs: dose 20mg/1 time/day for 8 weeks.
Peptic ulcer disease with Hebicobacter pylori: In triple combination therapy with amoxicillin and clarithromycin, the usual dose is 20mg twice daily for 1 week or 40mg once daily for 10 days.
For treatment of Zollinger-Ellison syndrome: initial dose of 40 mg once daily, then adjusted according to response.
Children under 12 years old: not recommended.
Elderly people: no need to adjust the dose.
Patients with severe hepatic impairment: maximum dose of 20mg/day, in mild cases, no dose adjustment is required.
Pregnant and lactating women:
● Should only be used when absolutely necessary for pregnant women.
● Breastfeeding women: should not use, in case of necessity, stop breastfeeding.

Common: digestive disorders, diarrhea, headache, dizziness..

Ketoconazole, digoxin, diazepam, phenytoin

Currently there is no specific antidote, in case of overdose should treat symptomatically and use general supportive measures.
Above is important information about the drug Zaclid, the use of which should be consulted by a doctor, pharmacist. Because using the right and enough will help bring better treatment results.