What is Thyrozole 5mg for?

What is Thyrozole? Thyrozol, also known as thiamazole, belongs to the class of antithyroid drugs. What is Thyrozole 5mg for? Thyrozole is effective in the treatment of hyperthyroidism, especially without goiter or small thyroid nodules, or in patients who are about to undergo surgery, prepare before radioactive iodine treatment, or alternately after radioactive iodine treatment. .
In addition, Thyrozol is also used in the prevention of latent hyperthyroidism, auto thyroid nodules and a history of hyperthyroidism when exposed to iodine.

Thyrozol 5mg is prepared in the form of film-coated tablets with a strength of 5mg. Use Thyrozol as directed on the product packaging instructions. The usual starting dose is 10-14mg/day depending on the severity of the disease and the amount of iodine used, maintenance is about 5-20mg/day in combination with levothyroxine or 2.5-10mg/day. In patients with iodine-induced hyperthyroidism, higher doses may be required.
For conservative treatment from 6 months to 2 years, short-term treatment if goiter is large and tracheal obstruction, it is best combined with levothyroxine. For the time before surgery: Usually 3-4 weeks or longer, treatment can be terminated and high iodine dose used for 10 days to compensate for the risk of increased brittleness and haemorrhage of thyroid tissue caused by thiamazole before surgery (also called iodine plummer therapy). At this time, the doctor will perform surgery as soon as the thyroid level is reached. Time before radioactive iodine treatment: thionamide derivatives may reduce the radiosensitivity of thyroid tissue. Interval time after radioactive iodine treatment: about 4-6 months depending on the disease condition and predicted time until radioactive iodine therapy starts to take effect. For prophylactic doses: 10-20mg or 1 gram perchlorate for about 10 days. Patients with hepatic or renal impairment or the elderly should keep the dose as low as possible and monitor it. In the treatment of hyperthyroidism with a high starting dose, it is necessary to divide the daily dose and take it at regular intervals throughout the day. Use Thyrozol exactly as directed by your doctor, do not use more, smaller or longer than prescribed. Thyrozol can be taken with or without food or as directed by your doctor. Use Thyrozol regularly to get the most benefit and stop taking it if any new symptoms appear or your condition does not improve after 7 days. Absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.

Some unwanted effects that may occur when using Thyrozol include:
Allergic skin reactions such as itching, red skin, hives,... Joint pain that progresses gradually and even After many months of treatment is a common side effect. Agranulocytosis Taste disturbance Drug use fever Thrombocytopenia Pancytopenia Lymphadenopathy Autoimmune insulin syndrome Neuritis Polyneuropathy Acute salivary gland swelling Cholestatic jaundice Hepatitis toxicity Severe forms of allergic skin reactions including generalized dermatitis, drug-induced lupus erythematosus, alopecia. Before prescribing a medication, doctors always weigh the benefits and effectiveness of Thyrozol more than the risk of side effects. However, some cases when using Thyrozol can still occur unwanted effects. Therefore, when unusual symptoms appear, especially when a severe allergic reaction occurs with accompanying signs such as severe dizziness, difficulty breathing, rash, swelling or itching of the face and throat. , tongue, ..., the patient should immediately notify the doctor or nurse for immediate medical intervention.

Some notes when using Thyrozol include:
Report a history of allergy to Thyrozol or any other allergies. Thyrozol may contain ingredients that are inactive and could cause an allergic reaction or other serious problems. Notice the medications you are taking including prescription, nonprescription, herbal and dietary supplements. Thyrozole should only be used for a short time under careful medical supervision if the patient has a large goiter and is associated with tracheal obstruction, because of the risk of tumor growth. Do not use the drug if you have a history of mild hypersensitivity reactions. Discontinue use if agranulocytosis is confirmed, bone marrow toxicity occurs. Do not overdose, as it may cause clinical or latent hyperthyroidism and goiter growth. Late hypothyroidism may occur after treatment if other surgical methods are not used. Thyrozol should not be used if the patient has hereditary galactose intolerance, glucose-galactose malabsorption, lapp lactase deficiency. For lactating women use the lowest effective dose, do not use extra thyroid hormone. In pregnant women, there are not enough studies to determine the risks of using the drug during pregnancy. Before using Thyrozol, always consult with your doctor to weigh the benefits and risks. If you forget to take a dose of Thyrozol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue taking it as scheduled. Do not take more medicine than prescribed. Thyrozol overdose or ingestion can cause serious symptoms such as nausea, vomiting, abdominal pain, shortness of breath, fainting,...

Drug interactions can decrease the effectiveness of Thyrozole, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including over-the-counter medicines, vitamins, prescription drugs, and herbal products. Do not start, stop or change the dose of any medicine without your doctor's consent.
In addition, iodine deficiency can increase the thyroid's response to Thyrozole, while excess iodine reduces the response. The metabolism and elimination of other drugs may be accelerated in hyperthyroidism. Thyrozole may normalize the increased activity of anticoagulants in patients with hyperthyroidism.

Store Thyrozol at room temperature, away from light and away from moisture. Do not store Thyrozol in a humid place or in the freezer and keep away from heat and open flames. Different medicines will have different ways to store them, so read carefully the storage instructions for Thyrozol on the packaging, or ask your pharmacist. Keep Thyrozole out of the reach of children and family pets. When the medicine has expired or is damaged and cannot be used anymore, dispose of it and dispose of it properly. Do not arbitrarily dispose of Thyrozol into the environment such as water pipes or toilets unless requested. Please consult your waste disposal company or pharmacist on how to safely dispose of Thyrozol to help protect the environment.
In short, the drug Thyrozol, also known as thiamazole, belongs to the subgroup of antithyroid drugs. Thyrozol is effective in the treatment of hyperthyroidism, especially without goiter or small goiter, or in patients who are about to undergo surgery, prepare before radioactive iodine treatment, or alternately after radioactive iodine treatment. However, thyrozole can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of unwanted effects and at the same time increase your chances of getting worse. effective for treatment.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.