What does a negative hepatitis virus test result mean?

Question
Hello doctor,
Patient is suspected of having a small liver fluke infection. Evaluation of viral markers showed HBsAg (-), anti-HBs (+), anti-HAV IgM (-), and anti-HCV Ab (-) and normal serum tumor markers. Stool test for eggs by direct method was negative 3 times. What does a negative hepatitis virus test result mean? Thank you doctor.
Tran Hien (2001)
Answer
Answered by Resident Doctor, Doctor Nguyen Thi Thuy Hang - Laboratory Department - Vinmec Times City International General Hospital.
Hello,
With the question “What does a negative hepatitis virus test result mean? ”, the doctor would like to answer as follows:
Currently, your results show that you are not infected with hepatitis A, hepatitis B and hepatitis C viruses. You already have antibodies against hepatitis B virus. , however, here only qualitative results are given without accompanying semi-quantitative indicators, so the protective effect cannot be concluded.
About the baby liver fluke test: Although the stool smear test for eggs is still a basic test to diagnose the disease and you have taken 3 samples in a row. However, this test should be done in a laboratory with a parasitology department. Furthermore, if the number of fluke eggs is too small, it may lead to false negatives. You need to combine other tests such as blood count, serology and imaging tests (ultrasound, CT scan, MRI) to make a more accurate diagnosis.
If you still have questions about the negative hepatitis virus test result, you can go to a hospital under Vinmec Health System for further testing and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!