Signs of Choline poisoning

The article was professionally consulted by Specialist Doctor I Do Van Manh - Emergency Medicine Doctor - Emergency Resuscitation Department - Vinmec Ha Long International General Hospital.

Choline is similar to a B vitamin, playing an important role in many chemical reactions in the body. However, consuming too much choline can lead to poisoning.

Choline is similar to the B vitamins, it can be made in the liver, it is also found in foods like liver, muscle meat, fish, nuts, beans and eggs.
Choline is used for liver disease, including chronic hepatitis and cirrhosis. It is also used for depression, dementia, Alzheimer's disease, Huntington's disease, Tourette's disease (a brain disorder called cerebellar ataxia), certain types of epilepsy, and schizophrenia.
Athletes use it for bodybuilding and delaying fatigue in endurance sports. Choline is used by pregnant women to prevent neural tube defects in babies and it is used as a supplement in infant formula. Other uses include preventing cancer, lowering cholesterol and controlling asthma.
Choline is a nutrient that is available in a number of foods and is available as a supplement. Our body can produce it on its own but not enough to meet our daily needs. Choline helps muscles contract, activates pain responses, and plays a role in the brain's memory and thinking functions. Most choline is metabolized in the liver, where it is converted to phosphatidylcholine, which helps build fat-carrying proteins and break down cholesterol.

Choline is safe for most adults when taken by mouth or intravenously in appropriate amounts. Taking high doses of choline by mouth may not be safe for adults. If taken in doses that exceed the daily intake are more likely to cause side effects such as sweating, fishy body odor, stomach upset, diarrhea and vomiting.
There is some concern that increasing the amount of choline in the diet might increase the risk of colon and rectal cancer. One study found that women who ate a diet high in choline had an increased risk of colon cancer. However, this idea still requires more research to determine the effect of diet on colon cancer.

For children, choline is safe for most children when taken by mouth in appropriate amounts. Taking high doses of choline may not be safe for children due to the increased risk of side effects.
Pregnant and lactating women, choline is safe when taken orally and used appropriately. The maximum dose is 3 grams per day for pregnant and lactating women and 3.5 grams per day for women 19 years of age and older.

Excess choline consumption can lead to low blood pressure (hypotension) and liver toxicity. It can also lead to a higher risk of cardiovascular disease. In addition, too much choline can also lead to the following symptoms:
Fishy body odor Sweating Salivation Digestive disorders Diarrhea Nausea and vomiting In addition, people with the following conditions may be more susceptible to the side effects of choline toxicity:
Kidney disease Liver disease Depression Parkinson's disease Choline plays a central role in liver health, muscle function and nerve development. Certain groups including men, postmenopausal women, athletes, heavy drinkers and women who are pregnant or breastfeeding are at higher risk for choline deficiency if they are not given it. enough from his diet. However, consuming too much choline can also cause harmful effects on health.
If you do not know how to supplement with choline for the right dose for each age, you should consult and seek the advice of a doctor at Vinmec International General Hospital. With many years of experience working in the Nutrition industry, the doctor will support and give you the most appropriate advice before taking to avoid causing choline poisoning.

Source: gbhealthwatch.com - webmd.com - hsph.harvard.edu