Signs of multi-organ failure and how to treat it

This is an automatically translated article.

The article was professionally consulted by Specialist Doctor I Nguyen Hong Phuc - Emergency Resuscitation Doctor, Emergency Resuscitation Department - Vinmec Phu Quoc International General Hospital. The doctor has nearly 20 years of experience in Emergency Resuscitation.

Multiple organ failure is a syndrome that occurs in many patients undergoing emergency resuscitation. Diseases caused by many different causes such as: Infections, parasites or multiple traumas, burns,...

1. What is multiple organ failure?

Multiorgan dysfunction syndrome (MODS) is an acute development of a pathological process in which at least two or more organs fail and this failure persists for at least a short period of time. 24 hours during which an infectious etiology may or may not be present.
When the body has long-term multi-organ failure, it will lead to septic shock. Septic shock is a severe stage of multi-organ failure.

Sốc nhiễm khuẩn — Suy đa tạng lâu sẽ dẫn tới bị sốc nhiễm khuẩn

2. Causes of multi-organ failure

Infection is the leading cause of multi-organ failure. When bacteria enter the bloodstream, causing systemic inflammatory responses that release inflammatory cytokines, there is an imbalance between inflammatory factors and anti-inflammatory factors (anti-inflammatory factors are weaker than anti-inflammatory factors). inflammatory) causes secondary organ damage and creates a multi-organ failure spiral.

3. Subjects at risk of multiple organ failure

Patients over 55 years old with severe trauma Sepsis Blood pressure drop lasting more than 24 hours Lack of oxygen supply and use after shock resuscitation. Undergo major, lengthy surgery. Aortic clamping lasts more than 1.5 hours. The patient has severe liver dysfunction.

Nhiễm khuẩn huyết ở trẻ em — Bệnh nhân nhiễm khuẩn huyết có nguy cơ bị suy đa tạng

4. Treatment of multiple organ failure

Treatment of multi-organ failure is mainly pre-prophylaxis so that multi-organ failure does not occur. Doctors need to identify and treat the underlying diseases early, provide supportive treatment for organs, in order to inhibit the progression of systemic inflammatory response syndrome, improve multi-organ dysfunction syndrome, and prevent prevent multi-organ failure.
Quickly ensure the patient's vital functions are breathing and circulation to maintain the patient's life.

4.1 Treatment and support for respiratory function by measures

Give the patient oxygen therapy (glass oxygen, simple mask, respirator bag), continuous positive pressure (CPAP) ventilation with assisted oxygen connection. Breathe machine.

Máy thở — Điều trị, hỗ trợ chức năng hô hấp bằng biện pháp thở máy

4.2 Supports cardiovascular function

Volume replacement Use vasopressors.

4.3 Adjunctive treatment of renal dysfunction

Avoid taking nephrotoxic antibiotics. Continuous hemodialysis. Multiple organ failure is a dangerous syndrome that often occurs in patients with serious diseases in the body. The disease needs to be diagnosed and evaluated by a doctor to proactively prevent it from the very beginning.
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This article is written for readers from Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.