Can Duphaston pills be taken during pregnancy?

The article was professionally consulted with Master, Doctor Dinh Thanh Ha - Obstetrician and Gynecologist - Department of Obstetrics and Gynecology - Vinmec Nha Trang International General Hospital.

In the process of assisted reproduction in women, the doctor may prescribe Duphaston after ovulation or during fertilization to support the luteal phase of pregnancy, help the uterine lining to secrete and maintain the pregnancy. as well as preventing early miscarriage if pregnant. So is it okay to take duphaston while pregnant?

Duphaston is the name for a generic medicine called Dydrogesterone. Duphaston is a synthetic hormone that resembles progesterone (a sex hormone that is made naturally in the body). More specifically, Duphaston has a progesterone-like effect on the endometrium and has a supportive pregnancy effect. The effects of Duphaston include:
Treatment of some syndromes that cause menstrual cycle disturbances due to a lack of progesterone in the body. Examples include premenstrual syndrome, anovulation, breast tenderness or perimenopause as well as benign breast disease. Duphaston is used to help regulate processes in women with low progesterone levels and to maintain a healthy body. Duphaston drug also supports the treatment of luteal insufficiency causing infertility or the treatment of endometriosis. Duphaston is taken during pregnancy in cases such as threatened miscarriage or repeated miscarriages where the cause is determined to be luteal insufficiency.

Normally, Progesterone-containing drugs such as Duphaston work to help reduce uterine contractions, prevent miscarriage, increase arterial blood and glycogen in the female uterine lining to ensure nutrients for the fetus, create a plug. cervical mucus to avoid bacterial invasion. Therefore, it is necessary to take duphaston during pregnancy in case of threatened miscarriage.
So does duphaston affect the fetus? In fact, Duphaston pregnancy care should not affect the fetus. However, each person has different drug interactions, so to ensure absolute safety, taking duphaston during pregnancy should be prescribed and advised by a doctor after conducting a health check. health of pregnant women.

As a medical treatment for many different conditions of the body related to the mechanism of progesterone production such as maintaining a healthy pregnancy, bleeding during pregnancy or women with a history of miscarriage, pregnancy previously saved. At the same time, the drug also relieves cramps, severe abdominal pain during menstruation.
However, using Duphaston medicine can cause patients to experience some unwanted side effects such as nausea, headache, abdominal pain, unusual jaundice and skin side effects. Therefore, when using this drug, users should note the following issues:
Must be cautious in using Duphaston for people with severely damaged liver function, not indicated to use the drug during Pregnant with no signs of miscarriage. Patients with a personal or family history of breast cancer, breast carcinoma, liver disease, or an allergy to Duphaston or any of its ingredients. Women with a history of blood clots, blood clots or strokes should also not use Duphaston. The drug should be used in the right dose, because if the wrong dose of Duphaston is used, it can have a negative impact on the fetus as well as the woman's health.

Although it does not affect the health of women and fetuses, not all subjects can use Duphaston to maintain pregnancy or treat diseases. The use of the drug requires a prescription from a specialist. The first trimester is the most sensitive time during pregnancy. In order for mother and baby to be healthy, parents need to pay attention to:
Understand early signs of pregnancy, pregnancy poisoning, bleeding during pregnancy. Timely, correct and sufficient first prenatal check-up, avoiding too early/too late. Fetal malformation screening at 12 weeks detects dangerous fetal malformations that can be intervened early. Distinguish between normal vaginal bleeding and pathological vaginal bleeding for timely intervention to maintain pregnancy. Screening for thyroid disease in the first 3 months of pregnancy avoids dangerous risks before and during delivery. Vinmec currently has many maternity packages (12-27-36 weeks), in which the 12-week maternity package helps monitor the health of mother and baby right from the beginning of pregnancy, early detection and timely intervention of health issues. In addition to the usual services, the maternity monitoring program from 12 weeks has special services that other maternity packages do not have such as: Double Test or Triple Test to screen for fetal malformations; Quantitative angiogenesis factor test to diagnose preeclampsia; thyroid screening test; Rubella test; Testing for parasites transmitted from mother to child seriously affects the baby's brain and physical development after birth.
For more information about the 12-week maternity package and registration, you can contact the clinics and hospitals of Vinmec health system nationwide.