Pramipexole ER: Uses, indications and cautions when using

Pramipexole is used in the treatment of Parkinson's disease, helping to improve mobility and reduce tremors, stiffness, slow and unsteady movements. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance in the brain.

What does Pramipexole do? Pramipexole is used to treat Parkinson's disease, improves mobility, and can reduce tremors, stiffness, slow and unsteady movements. In addition, it can also reduce the number of times when it is impossible to move. Pramipexole is a dopamine agonist that works by restoring the balance of a certain natural substance (dopamine) in the brain.

Pramipexole is to be taken by mouth with or without food as directed by your doctor, usually once daily. The patient should swallow the tablet whole, do not crush, chew or break the tablet. Because, doing so can release the drug all at once, increasing the risk of side effects.
Dosage will be based on your medical condition and response to treatment. It may take a few weeks to see the full effects of the medication. Taking Pramipexole with food may reduce nausea. To reduce the risk of side effects such as low blood pressure and drowsiness when first used, your doctor will slowly increase your dose until the best dose is reached.
Use Pramipexole regularly to get the most benefit from it. Absolutely do not arbitrarily increase the dose or abuse the drug for a longer time than prescribed. This not only makes the condition improve faster, but also increases the risk of unwanted effects. If you stop taking it for several days, you may need to slowly increase your dose back to your previous dose. Talk to your doctor about how to start the medication again. Do not stop taking this medication without your doctor's approval. Although very unlikely, if you suddenly stop taking the medicine, a serious reaction can occur including fever, muscle stiffness, and confusion. Report any such reactions to your doctor immediately.
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Some unwanted effects that may occur when using Pramipexole include:
Nausea, vomiting Dizziness Drowsiness Dizziness Constipation Headache Cough Dry mouth Serious side effects: mental status changes (such as hallucinations, depression, confusion), urges to unusual sensations (such as increased gambling, increased libido), muscle cramps or spasms, abnormal posture changes (such as neck or body forward bend), swelling of the ankle or foot. Before prescribing, doctors always weigh the benefits of Pramipexole more than the risk of side effects. However, in some cases, when taking Pramipexole, unwanted effects may still occur. Therefore, when you see unusual signs, especially when an allergic reaction occurs with accompanying symptoms such as rash, difficulty breathing, severe dizziness, itching or swelling of the face, tongue, and throat. ,... In this case, the patient should immediately notify the medical staff for immediate intervention.

Some notes when using Pramipexole include:
Report a history of allergy to Pramipexole or any other allergies. The product may contain inactive drug ingredients and may cause allergic reactions or other serious problems. Report medical history especially low blood pressure, heart problems (such as irregular heartbeat, heart failure), kidney problems, mental status disorders (such as hallucinations, confusion, schizophrenia, psychosis), sleep disorders (such as sleep apnea, narcolepsy) To reduce the risk of dizziness and lightheadedness, slowly change position from lying down to sitting or standing up. Pramipexole can cause sudden drowsiness without warning. So do not drive, use machinery or do any work that requires alertness. The risk of sleep disturbance is increased with alcohol or other drugs that can make you drowsy. Therefore, it is necessary to limit alcohol and the use of stimulants. Before having surgery, tell your doctor or dentist about all the medicinal products you are taking including prescription drugs, over-the-counter medicines, vitamins, and herbal products. other. Elderly people are more likely to experience dizziness and hallucinations while using this medicine. Therefore, consideration should be given to the use of Pramipexole in the elderly. Pregnant and lactating women should only use it when absolutely necessary. Pramipexole can pass into breast milk and adversely affect the infant, as well as affect milk production. Therefore, breast-feeding while taking Pramipexole is not recommended. People with Parkinson's disease may have an increased risk of developing skin cancer. If you notice a change in the shape or size of a mole or other unusual changes in your skin, tell your doctor. medical staff. If you forget to take a dose of Pramipexole, take it again as soon as possible within 12 hours. However, if it has been more than 12 hours since your last dose, skip the missed dose and take your next dose at the same time as the original dose. Absolutely do not use twice the dose of the drug than the treatment regimen. Using an overdose of Pramipexole can cause serious symptoms such as nausea, vomiting, abdominal pain, weakness,...

Drug interactions can decrease the effect of Pramipexole, or increase the effect of unwanted effects. Tell your doctor about all other medicinal products you are using, including prescription and over-the-counter medicines, vitamins, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's consent.
Some medicinal products that may interact with Pramipexole include:
Antipsychotics such as chlorpromazine, haloperidol, thiothixene. Cimetidine Metoclopramide Stimulants such as alcohol, marijuana,... Antihistamines such as cetirizine, diphenhydramine Sleeping or anxiety relievers such as diazepam, alprazolam, zolpidem Muscle relaxants such as carisoprodol, cyclobenzaprine Opioid analgesics: hydrocodone, codeine

Store Pramipexole at room temperature, away from moisture and light. Do not store Pramipexole in a humid place or in the freezer. Each medicine will have different storage methods, so read the Pramipexole storage instructions on the package carefully, or ask your pharmacist. Keep Pramipexole out of the reach of children and household pets. When the medicine has expired or cannot be used anymore, dispose of the medicine properly. Pramipexole should not be disposed of in an environment such as a water pipe or toilet unless requested to do so. Ask your waste disposal company or pharmacist for advice on how to safely dispose of Pramipexole to help protect the environment.
In summary, Pramipexole is effective in the treatment of Parkinson's disease, helping to improve mobility and reduce tremors, stiffness, slow and unsteady movements. Pramipexole is a dopamine agonist that works by helping to restore the balance of a natural substance dopamine in the brain. However, Pramipexole can cause some unwanted effects and drug interactions, so tell your doctor what medicinal products you are taking to reduce the risk of side effects and increase the effectiveness of your treatment. treatment course.

Above is important information about Pramipexole drug, patients should pay attention and consult carefully with doctors and pharmacists before taking the drug to promote the best effect in treatment.
Vinmec International General Hospital is a high quality medical care address with a team of doctors and pharmacists with many years of experience and good expertise. When having health problems, customers can contact the hospital to be examined and have the best indications for taking medicine.

Reference source: webmd.com