Syntina drug use

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Syntina drug is indicated for mucolytic in acute and chronic lung and bronchial diseases with increased mucus secretion... Let's learn about the uses and notes when using Syntina through the article below. .

1. Uses of Syntina


Syntina medicine contains the active ingredient Acetylcysteine, which is prepared in two dosages, Syntina 200 and Syntina 100.
Active ingredient Acetylcysteine ​​belongs to the N - acetyl derivative of L - cystin - a natural Amino Acid. The drug works by way of reducing the viscosity of sputum in purulent or non-purulent lungs by cleaving the disulfide bridge in the mucoprotein, facilitating the expulsion of sputum by the cough response.
Acetylcysteine ​​is also used topically in the treatment of non-tears. Acetylcysteine ​​​​protects the liver from paracetamol overdose through the mechanism of maintaining or restoring liver concentrations of Glutathion - the active ingredient needed to inactivate the intermediate metabolite of Paracetamol which is toxic to the liver.
Syntina is indicated for mucolytic therapy in acute and chronic bronchopulmonary diseases accompanied by increased mucus secretion.

2. Dosage of Syntina


The recommended dosage of Syntina depends on the age and condition of the patient as follows:
Treatment of mucus secretion:
Adults and children over 14 years old: Oral 200mg/time x 2-3 times/day; Children from 6-14 years old: 200mg/time x 2 times/day or 100mg/time x 3 times/day; Children from 2 to 5 years old: Take 100mg/time x 2-3 times/day. Treatment of increased mucus secretion:
Children over 6 years old: 200mg/time x 3 times/day; Children 2-5 years old: Take 100mg/time x 4 times/day. Paracetamol overdose reduction: Initial dose is 140mg/kg, subsequent maintenance doses of 70mg/kg are repeated every 4 hours, for a total of 17 doses.

3. Undesirable effects of Syntina


Syntina can cause some side effects as follows:
Common: Vomiting, nausea; Uncommon: Headache, headache, tinnitus, runny nose, stomatitis, urticaria, rash; Rare: Chills, fever, bronchospasm with systemic anaphylaxis. Reduce the possibility of unwanted effects through the following measures: Using diluted Acetylcysteine ​​solution helps to reduce the possibility of causing vomiting due to the drug. For anaphylactic reactions, the patient should be taken to a medical facility as soon as possible. Inform your doctor in case you experience any side effects while taking Syntina.

4. Notes when using Syntina


4.1. Contraindications The use of Syntina is contraindicated in patients with hypersensitivity to Acetylcysteine ​​or any component of the drug, patients with a history of bronchial asthma (risk of bronchospasm with all Acetylcysteine ​​​​functions).
4.2. Precautions for use Use caution and closely monitor patients at risk for the onset of bronchial asthma. In the case of using Acetylcysteine ​​in patients with a history of allergies, if symptoms of bronchospasm appear, use a nebulized bronchodilator such as Ipratropium, Salbutamol and stop treatment with Acetylcysteine ​​immediately.
Treatment with Acetylcysteine ​​can cause a lot of thin sputum in the bronchi, it is necessary to remove the sputum to open the bronchi in case the patient has a reduced ability to cough.
For pregnant women, lactating women, children under 2 years: It is not recommended to use Syntina in the treatment of these subjects.

5. Syntina drug interactions


Syntina may cause some interactions with Tetracycline, Nitroglycerin and cough medicine.
Drug interactions occur that increase the risk of having an effect and reduce the therapeutic effect of Syntina, so to ensure safety and effectiveness in treating patients, it is necessary to inform the doctor about drugs and foods. were using before taking Syntina.

This article is written for readers from Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.

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