Uses of Latoxol

Latoxol is the preferred drug class indicated for the treatment of acute and chronic diseases of the respiratory tract such as acute exacerbations of chronic bronchitis, bronchial asthma. So how should Latoxol be used in what dosage?

1.1. What is Latoxol? Latoxol belongs to a group of drugs that act on the respiratory tract. The drug has the main ingredients:
Main active ingredients: Ambroxol hydrochloride with a content of 360 mg Active ingredients: Acesulfam potassium, Sucrose, Maltodextrin, malic acid, citric acid monohydrate, sodium citrate, glycerin, sodium metabisulfite, EDTA, Sorbitol solution 70 %, Strawberry flavor, Distilled water). Latoxol is prepared in the form of syrup in glass bottles with a capacity of 60ml. Latoxol is recommended for use in children 2 years of age and older and adults. The drug Latoxol has a form of Latoxol kids specifically for children.
1.2. What does Latoxol do? Ambroxol is a metabolite of Bromhexin, which has the same effects and uses as Bromhexin. Ambroxol has expectorant and mucolytic effects but has not been fully demonstrated.
The drug works quite well in patients with mild and moderate obstructive pulmonary disease, but there is no obvious benefit in patients with severe obstructive pulmonary disease. Latoxol is rapidly and almost completely absorbed in therapeutic doses.
Latoxol is used without prescription in the following cases:
Acute and chronic diseases of the respiratory tract accompanied by abnormal bronchial secretions, especially in acute exacerbations of chronic bronchitis, asthma bronchi, asthmatic bronchitis. Post-operative and emergency patients to prevent lung complications.

2.1. How to take Latoxol Oral drug Absorption of the drug is independent of meals. However, it is recommended to take the drug after meals. Use a graduated cup to get the most accurate dose. Each course of treatment should not last more than 4-5 days without consulting a doctor. 2.2. Dosage of Latoxol The dose of the drug is adjusted to suit the individual patient and the condition of the disease. Dosage recommendations are given as follows:
Adults and children over 10 years: 5 mL/time x 2-3 times/day. Children 5-10 years old: 2.5 mL/time x 2-3 times/day. Children under 2 years old: 2.5 mL/time, 2 times/day (corresponding to 15 mg ambroxol hydrochloride/day). Children 2-5 years old: 2.5 mL/time, 3 times/day (corresponding to 22.5 mg ambroxol hydrochloride/day). Children 6-12 years old: 5mL/time, 2-3 times/day (corresponding to 30-45 mg ambroxol hydrochloride/day). Adults and adolescents over 12 years: In the first 2-3 days: 10mL/time, 3 times/day (corresponding to 90 mg ambroxol hydrochloride/day). Then, 10mL/time, 2 times/day (corresponding to 60 mg ambroxol hydrochloride/day). At doses for adults and adolescents over 12 years of age: for increased effectiveness, 20 mL/time, 2 times/day (corresponding to 120 mg ambroxol hydrochloride/day). Handling missed dose:
Take as soon as you remember, do not take too close to the next dose. Do not take a double dose to make up for a missed dose.
Treatment of overdose:
According to medical guidelines, the duration of basic drug use is not limited. However, patients should not use it for more than 4-5 days without medical advice.

Hypersensitivity to the main active ingredient Ambroxol or any of the excipients listed above of Latoxol.
Peptic ulcer disease progression.
Patient is coughing up blood .
Only use the drug for children under 2 years old under the supervision of medical staff.

There have been reports of serious skin reactions with the use of ambroxol such as: erythema multiforme, Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustular syndrome calculation (AGEP). Therefore, in the event of progression of these symptoms or signs on the skin, ambroxol should be stopped immediately and medical help should be sought.
In cases where bronchial motility is disturbed and secretions are greater than ambroxol should be used with caution, since obstruction of secretions may occur.
In the case of patients with kidney failure or severe liver disease, ambroxol should only be used as directed by a doctor or when absolutely necessary.
Patients with rare hereditary problems of fructose intolerance, or glucose-galactose malabsorption or sucrase-isomaltase deficiency, should not use this product because it contains sucrose and sorbitol.
Care should be taken to use with people with gastrointestinal ulcers and patients with coughing up blood. Because ambroxol can dissolve fibrin clots and cause bleeding to return or become heavier. Ambroxol should only be treated for a short period of time, if not, re-examination should be performed.
Pregnancy: Ambroxol crosses the placental barrier. Paraclinical studies have shown no evidence of direct or indirect adverse effects on the fetus or embryo. However, the use of the drug with caution during pregnancy should be considered. During the first trimester of pregnancy, use of ambroxol is not recommended.
Lactation: Ambroxol passes into breast milk in test animals. Use of ambroxol is not recommended during lactation.
Interactions when using Latoxol with other drugs:
Concomitant use of ambroxol with antitussive drugs can lead to dangerous accumulation of secretions due to suppressed cough reflex. Therefore, concomitant use should be undertaken after a risk-benefit assessment. Taking ambroxol with antibiotics (amoxicillin, cefuroxime, erythromycin, doxycycline) increases the concentration of antibiotics in the lung parenchyma. Do not combine ambroxol with an antitussive (such as codeine) or an expectorant (such as atropin): The combination is not reasonable.

A few cases when using Latoxol, patients may experience a few side effects such as:
Nervous system: Taste disturbance. Gastrointestinal tract: Nausea, numbness in the mouth. Respiratory, thoracic, mediastinal: Numbness in throat. Usually these reactions are quite mild and will go away quickly after a period of taking the drug. Therefore, patients need to pay special attention, if there are unusual problems, they should discuss with the doctor for appropriate indications.
Hopefully, the above sharing will help users better understand the mechanism of action of Latoxol drug as well as how to use it to get high efficiency and safety for the treatment process.