Uses of Triptorelin

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Triptorelin is a medication that contains the active ingredient Diphereline, which is used to treat prostate cancer or support fertility by affecting the immune system.

1. What is Triptorelin?

Triptorelin is a drug containing the active ingredient Diphereline, which works in the treatment of cancer by affecting the immune system. It is indicated in the treatment of metastatic prostate cancer by administering an attack dose before the long-acting form is used. The effect is more effective and lasts longer if the patient has not been treated with hormones before. On the other hand, for assisted reproduction, the use of triptorelin in combination with gonadotrophins (hMG, FSH, hCG) during the ovulation induction period for subsequent IVF is a real process. currently transplanting embryos.

2. How to use Triptorelin

Prostate cancer 0.1mg subcutaneously every day from day 1 to day 7 before switching to a long-acting form.
Assisted reproductive phase Subcutaneous injection 1 vial/day in combination with gonadotrophin therapy from the second day of the menstrual cycle with ovarian stimulation in the first phase until the day before the day of presumed ovulation . The average duration of treatment is estimated at 10 to 12 days.

3. Triptorelin side effects

Prostate cancer Initiation of treatment may aggravate clinical symptoms, especially bone pain. In addition, it may cause urinary obstruction, weakness or paresthesia in the lower extremities. This condition is usually short-lived and will clear up on its own after 1 to 2 weeks of continued treatment. However, transient exacerbations may still occur and should be observed with caution in patients with threatened neurological deficits or in those with urinary retention.
Assisted reproductive phase Hot flashes or weakness are common. In the case of concomitant use with gonadotrophins may lead to ovarian hyperstimulation, pelvic and/or abdominal pain, ovarian hypertrophy.

4. Some notes when using Triptorelin

Patients with prostate cancer should be periodically monitored for testosterone levels in the blood not to exceed 1ng/ml. In addition, bone quality can be assessed by computed tomography of the prostate and ultrasound or rectal examination. Assisted Reproductive Phase: Ovulation induction needs to be done under the close supervision of a physician, with rigorous clinical and biological parameters checked regularly with tests such as rapid quantification of serum concentrations. plasma estrogen levels.

5. Interactions between Triptorelin and other drugs

The occurrence of drug interactions can change the effectiveness of the drug or increase the effect of side effects. Some drugs that can decrease the activity of Triptorelin include Metformin, Sulfadiazine, Rosiglitazone, Acetohexamide, Miglitol, Chlorpropamide, Nateglinide, Tolazamide, Repaglinide, Phenformin, Phenformin. Therefore, before using the drug, the patient should inform the doctor about all the drugs that he is taking to minimize drug interactions. Triptorelin is a medicine that contains the active ingredient Diphereline, which is used to treat prostate cancer or support fertility by affecting the immune system. Patients need to strictly follow the instructions of the doctor and medical staff to get the best effect.
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