Uses of Usnadol

This is an automatically translated article.


Usnadol drug has the effect of reducing fever, reducing toothache, body aches, menstrual pain, flu. So to find out specifically what Usnadol drug is? how does it use? What are the side effects of Usnadol? Join us to learn the necessary information about the use of Usnadol through the article below.

1. What is Usnadol?


1.1. What is Usnadol?
Usnadol is a group of pain relievers, antipyretics, non-steroidal anti-inflammatory drugs (NSAIDs), which are used to treat gout and other bone and joint diseases.
Usnadol drug whose main ingredient is paracetamol is a very effective pain reliever and fever reducer. Drugs acting on thermoregulatory centers in the hypothalamus cause hypothermia, hyperthermia due to vasodilation, and increased peripheral blood flow, reducing body temperature in febrile individuals, but rarely lowering normal body temperature.
At therapeutic doses, the analgesic and antipyretic effect is similar to Aspirin, but Paracetamol has little impact on the cardiovascular and respiratory systems, does not change the acid-base balance, does not cause irritation, scratches or stomach bleeding. thick. Paracetamol is not effective in treating inflammation. Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. The half-life is 1.25 – 3 hours. The drug is metabolised in the liver and eliminated by the kidneys.
1.2. Usnadol drug use.
Usnadol drug with the main ingredient is paracetamol used to relieve pain in pain such as headache, migraine, sore throat, menstrual pain, pain after tooth extraction or dental procedures, toothache, pain muscle and tendon pain, injury pain, arthritis pain, sinusitis, cold pain, flu. Paracetamol is also widely used in the treatment of mild to moderate pain and fever.
Pain relief:
Paracetamol is used to temporarily relieve pain in the treatment of mild and moderate pain: headache, toothache, menstrual pain... The most effective drug is low-intensity pain relief of non-originating origin. by organs. Paracetamol has no effect rheumatic treatment. Paracetamol is an alternative to salicylates (preferred in patients with contraindications or intolerance to salicylates) for mild pain or fever.
Antipyretic:
Paracetamol is often used to reduce body temperature in febrile patients, does not affect the course of the underlying disease and can mask the patient's illness.

2. Usage of Usnadol


2.1. How to use Usnadol
Usnadol medicine has the main ingredient is paracetamol, which is usually taken orally. For patients unable to take oral medication, a rectal suppository may be used; however, the rectal dose required to obtain the same plasma concentrations may be higher than the oral dose. Paracetamol should not be used for self-administration for more than 10 days in adults or more than 5 days in children, unless directed by a pharmacist or doctor, as such prolonged and intense pain is likely. It is a sign of a medical condition that requires a doctor's diagnosis and supervised treatment. Do not use Usnadol with the main ingredient of paracetamol for adults and children to self-treat a high fever above 39.5 degrees Celsius, a fever lasting more than 3 days or a recurring fever, because such a fever may be a sign of a serious illness that requires prompt diagnosis by a doctor. To minimize the risk of overdose, children should not be given more than 5 doses of paracetamol to relieve pain or reduce fever within 24 hours. For pain or fever relief in adults and children over 11 years of age, the usual dose of paracetamol orally administered orally is 325 - 650 mg every 4 to 6 hours as needed but not to exceed 4 g a day. Single doses greater than 1 g may be useful for pain relief in some patients. Pain relief or fever in children can be taken orally or inserted rectally every 4 to 6 hours as needed: children 1 - 2 years old, 120 mg, children 4 - 11 months old, 80 mg; and children up to 3 months of age, 40 mg. The rectal dose for children under 2 years of age depends on the individual patient. The usual oral dose of paracetamol, as 650 mg extended-release tablets, for pain relief in adults and children 12 years of age and older is 1.3g every 8 hours as needed, not to exceed 3.9 g. everyday. Extended-release paracetamol tablets should not be crushed, chewed or dissolved in liquid.
2.2. Dosage of Usnadol
Dosage: Take the drug every 4 to 6 hours if needed
Adults: take 1 tablet. Do not take more than 6 tablets in 24 hours.
Children from 7 to 12 years old: take 1⁄2 tablets. Do not take more than 3 tablets in 24 hours
Minimum interval between 2 doses: 4 hours.
2.3. Overdose, missed dose and treatment when using Usnadol
Paracetamol overdose: due to a single toxic dose or repeated large doses of Paracetamol (7.5 - 10 g per day, for 1-2 days) or long-term medication. Dose-dependent hepatic necrosis is the most serious acute toxic effect of overdose and can be fatal.
Manifestations of overdose: nausea, vomiting, abdominal pain, cyanosis of the skin, mucous membranes and nails.
Treatment:
When intoxication with Paracetamol is severe, active supportive treatment is required. Gastric lavage in all cases, preferably within 4 hours after ingestion.
The main detoxification therapy is the use of Sulfhydryl compounds. N - acetylcysteine ​​is effective when taken orally or intravenously. The medicine must be given immediately if it has not been 36 hours since taking Paracetamol. Treatment with N - acetylcysteine ​​is more effective when the drug is given less than 10 hours after taking Paracetamol.
In addition, Methionine, activated charcoal or salt bleach can be used.
Caffeine overdose: rare, overdose symptoms are usually insomnia, restlessness, agitation and possibly delirium.

3. Contraindications of the drug Usnadol


Contraindications: Patients with hypersensitivity to the ingredients in the drug. The patient is deficient in glucose 6 phosphate dehydrogenase.
Drug interactions:
Long-term oral administration of high doses of Usnadol, whose main ingredient is paracetamol, slightly increases the anticoagulant effect of Coumarin and Indandion derivatives. Attention should be paid to the potential for serious hypothermia in concomitant use of phenothiazines and antipyretic therapy. Anticonvulsants such as: Phenytoin, Barbiturates and Carbamazepine. Isoniazid will increase the hepatotoxicity of Paracetamol. Heavy drinking and long-term alcohol use can increase the hepatotoxicity of Paracetamol. Avoid using paracetamol together with drugs or caffeinated drinks such as tea, coffee or some canned drinks. The half-life of caffeine is increased when combined with antibiotics such as: Ciprofloxacin - Enoxacin, Lomefloxacin - Norfloxacin - Ofloxacin. Do not combine caffeine with: Phenytoin, Fluvoxamine, Terbinafin, Cimetidine, Methoxsalen, birth control pills: Phenylpropanolamine, Ephedrine, Theophylline.
Pregnant and lactating women: Use the drug only when absolutely necessary. Driving and using machines: The drug does not affect the ability to drive and use machines.

4. Notes when using Usnadol


Notes and precautions:
For people with phenylketonuria - urine and people who have to limit the amount of phenylalanine put into the body should avoid taking Paracetamol with drugs or foods containing Aspartame. For some people with hypersensitivity such as asthma should avoid taking Paracetamol with medicines or foods containing sulfites. Should be used with caution in patients with pre-existing anemia and impaired liver and kidney function. Excessive alcohol consumption can increase the hepatotoxicity of Paracetamol, so avoid or limit alcohol consumption.
For drugs containing Paracetamol: Physicians should warn patients about signs of serious skin reactions such as Steven-Johnson syndrome (SJS), toxic skin necrosis syndrome (TEN) or Lyell's syndrome, acute generalized exanthematous pustulosis (AGEP)

5. Usnadol side effects


Skin rashes and other allergic reactions occur occasionally. Usually erythema or urticaria, but sometimes more severe and may be accompanied by drug fever and mucosal lesions. Patients sensitive to salicylates are rarely sensitive to paracetamol and related drugs. In rare cases, paracetamol has caused neutropenia, thrombocytopenia and pancytopenia. Uncommon: skin rash, nausea, vomiting, hematopoietic disorders (neutropenia, pancytopenia, leukopenia), anemia, kidney disease, nephrotoxicity with long-term abuse. Allergic reactions:
Very rarely people have an allergic reaction to paracetamol. Call your doctor right away if you have an allergic reaction after taking this medicine: difficulty breathing or swallowing, swelling of your face, lips, throat or tongue, hives, severe itching, peeling or blistering of your skin.
Paracetamol poisoning can happen when the patient takes too much.
If the patient suspects he or she has taken too much Usnadol, the main ingredient paracetamol, or notices any of the above symptoms, contact a poison control center or see a doctor immediately. If you have taken more than the recommended dose, go to the nearest emergency room, even if the person does not have any symptoms of liver damage.

6. How to store the drug Usnadol


Read the user manual carefully before use. And it is necessary to check the expiration date on the product's packaging. Keep out of reach of CHILDREN. Avoid pets, pets
Immediately notify your doctor or pharmacist of any unwanted effects encountered when using the drug. Usnadol has a shelf life of 36 months from the date of manufacture.
Usnadol stored at below 40 degrees C, preferably 15 - 30 degrees C,
Above is important information about Usnadol drug. If you have any further questions, the patient should discuss directly with the doctor for appropriate advice.

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