What is Acetaminophen and Oxycodone?

Acetaminophen and Oxycodone is a combination medicine used to relieve moderate to severe pain. In particular, Oxycodone is an opioid pain reliever and Acetaminophen is an antipyretic analgesic that enhances the effect of oxycodone.

Usual Adult Pain Relief Dose (quick release tablets):
2.5mg Oxycodone / Acetaminophen 300 or 325mg: 1 to 2 tablets taken every 6 hours; maximum dose of 12 tablets/day; 5mg Oxycodone / Acetaminophen 300 or 325mg: 1 tablet every 6 hours (as needed for pain relief); maximum dose of 12 tablets/day; 7.5mg Oxycodone / Acetaminophen 300 or 325mg: 1 tablet every 6 hours (as needed for pain relief); maximum dose of 8 tablets/day; 10mg Oxycodone / Acetaminophen 300 or 325mg: 1 tablet every 6 hours (as needed for pain relief); Maximum dose of 6 tablets/day. Usual Adult Pain Relief Dose (oral solution): 5mg Oxycodone / Acetaminophen 325mg (5ml): orally every 6 hours (as needed for pain relief); Maximum dose of Oxycodone 60mg / Acetaminophen 3900mg (60ml)/day. Note: User needs to determine dose in mg and mL before taking
Usual Adult Pain Relief Dose (extended release tablet form):
First dose: 2 tablets every 12 hours (every 12 hours) tablets containing 7.5 mg Oxycodone / 325mg Acetaminophen); Second dose: take as early as 8 hours after the initial dose (if needed). However, subsequent doses should be taken every 12 hours. Note: To avoid the risk of addiction and abuse, the lowest dose and for the shortest duration, consistent with the individual patient's treatment goals, should be taken.
Missed dose: Since Acetaminophen and Oxycodone are mainly used for pain relief, there is no risk of forgetting a dose.
Overdose: In case of an emergency, the patient should call 911 and go to the hospital immediately because an overdose of Acetaminophen can be fatal. The first signs of an Acetaminophen overdose include: Loss of appetite, nausea and vomiting, stomach pain, sweating, confusion or weakness. Later symptoms may include upper abdominal pain, dark urine, and yellowing of the skin or eyes.

Some side effects patients may experience when using Acetaminophen and Oxycodone include:
Common side effects, not dangerous: Dizziness, drowsiness, feeling tired, feeling extremely happy or sad. sadness, nausea, vomiting, stomach pain, constipation; or a headache. Rare, dangerous side effects: Allergic reactions (rash, difficulty breathing, swelling of the face, lips, tongue or throat). In some cases, Acetaminophen can cause serious skin reactions, even death. Stop taking the medicine and call your doctor at once if you experience noisy breathing, sighing, shallow breathing, feeling weak, fatigue, fever, unusual easy bruising or bleeding, confusion, problems on urination, liver, low cortisol levels, serotonin syndrome (agitation, hallucinations, sweating, fever, tremors, muscle stiffness, convulsions, loss of coordination, nausea and vomiting, diarrhea... ).

Before and while taking Acetaminophen and Oxycodone, patients should note:
Do not use the drug if you are allergic to Acetaminophen or Oxycodone have severe asthma or difficulty breathing; or there is a blockage in your stomach or intestines Tell your doctor if you have other medical conditions, especially: liver or kidney problems, drug or alcohol addiction, head injury or seizures, problems urinating convenient, in the thyroid, pancreas or gallbladder Pregnant and nursing women should not use Acetaminophen and Oxycodone without their doctor's approval.

Some of the most common Acetaminophen and Oxycodone drug interactions include:
Cold or allergy medicine, bronchial asthma, COPD medication or diuretics; Medicines for motion sickness, irritable bowel syndrome, or overactive bladder; Other narcotic drugs such as prescription opioid pain relievers or cough suppressants; Sedatives such as Valium, Lorazepam, Xanax, Diazepam, Alprazolam, Klonopin, Versed, and others; Medicines that make you sleepy or slow your breathing, such as: sleeping pills, muscle relaxers, drugs for emotional or mental illness; Medicines that affect serotonin levels in the body, for example a stimulant or medicine for depression, Parkinson's disease, serious infections, migraine headaches, nausea and vomiting. Before and during the use of Acetaminophen and Oxycodone, if there is any abnormality, the patient should immediately notify the doctor for timely treatment.