Yuvafem: Uses, indications and notes when using

Yuvafem, also known as estradiol, is a form of estrogen hormone used by women to improve vaginal symptoms of menopause such as vaginal dryness, burning, and itching. The above symptoms are signs of menopause as the body makes less estrogen. Estrogen taken by mouth, absorbed through the skin, or injected may have a higher risk of side effects because of the greater amount of estrogen absorbed, so topical products should be used first. in the vagina.

Yuvafem is available as a round, white, film-coated tablet that is used by inserting the tablet inside the vagina. Gently insert the tablet into the vagina as directed and press the plunger to release the medication. Dosage is based on the patient's medical condition and response to treatment, usually once daily for the first 2 weeks and twice a week thereafter.
Use Yuvafem regularly to get the most benefit from it. Absolutely do not arbitrarily increase the dose of the drug or abuse the drug for a longer time than the treatment regimen. This does not make the condition better, but also increases the risk of unwanted effects.

Some undesirable effects that may occur when using Yuvafem include:
Nausea or vomiting Abdominal bloating Diarrhea Diarrhea Chest tightness Headache Weight changes Serious side effects: mental status changes (such as depression, dementia), breast lumps, unusual vaginal bleeding (such as bleeding, sudden bleeding, recurrent bleeding), increased or new irritation or itching, odor, and vaginal discharge, stomach pain, persistent nausea, yellow eyes, dark urine, swelling of hands or ankles, increased urination. Yuvafem rarely causes serious problems with blood clots such as heart attack, stroke, deep vein thrombosis, pulmonary embolism, etc. However, if you develop any symptoms such as unusual sweating, chest pain spreading to your arm, sudden severe headache, weakness on one side of the body, difficulty speaking, confusion, sudden vision changes sudden onset (such as partial or complete blindness), pain or redness, swelling in the legs, tingling or weakness, numbness in the limbs, coughing up blood, trouble breathing, dizziness, or sudden fainting. Before prescribing medicine, doctors always weigh the benefits and effects of Yuvafem more than the risk of side effects. However, in some cases when using Yuvafem, unwanted effects may still occur. Therefore, when unusual signs appear, especially when a severe allergic reaction occurs with accompanying symptoms such as difficulty breathing, severe dizziness, rash, itching or swelling of the face, throat, tongue,... In this case, the patient should immediately notify the medical staff for immediate intervention.

Some notes when using Yuvafem include:
Report a history of allergy to Yuvafem or any other allergies. Yuvafem may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Report a medical history especially of unexplained vaginal bleeding, certain cancers (such as breast cancer, uterine or ovarian cancer), blood clots, stroke, heart disease, liver disease , kidney disease, family medical history (such as cancer, breast tumor, blood clot), family or personal history of a certain swelling disorder (angioedema), blood clotting disorder (such as anemia protein C or protein S), high blood pressure, diabetes, elevated cholesterol or high triglycerides, obesity, lupus, underactive thyroid, mineral imbalances (high or low blood calcium), problems with uterine fibroids (such as fibroids, endometriosis), gallbladder disease, asthma, epilepsy, migraine headaches, mental disorders (such as depression, dementia), a certain blood disorder It is a disorder of porphyria. Not smoking or using tobacco, the higher the estrogen associated with smoking, because this increases the risk of stroke, blood clots, high blood pressure and heart attack, especially in women over 35. Tell your doctor if you have had surgery or are immobile for a long time (such as a long flight). These conditions increase the risk of blood clots forming, especially if you are using an estrogen product. You may need to stop taking Yuvafem for a while or take special precautions. Yuvafem may cause melasma on the face and increased sensitivity to the sun. Therefore, it is necessary to limit time in direct sunlight, use sunscreen regularly, and other protective measures such as wearing sunscreen. If you are nearsighted or wear contact lenses, you may have vision problems or have difficulty wearing contact lenses, contact your ophthalmologist if eye problems occur. Yuvafem should not be used during pregnancy and lactation. Because the drug can reduce the quality and quantity of breast milk secreted. A few tests like blood pressure, breast exam, mammogram, pelvic exam, cervical smear, etc. to monitor your progress and check for side effects. Perform daily breast exams at home as directed by your doctor. Preventing or controlling high blood pressure, high cholesterol, and diabetes can help reduce your risk of heart disease and stroke. Lifestyle changes that can help control or prevent these conditions include reducing stress, eating a low-fat/salt diet, losing weight if overweight, exercising regularly, and stopping smoking. Keep your mind active and agile with mental exercises (such as reading, solving crossword puzzles) to help prevent dementia. Yuvafem can be harmful if swallowed or taken in excess. If you miss a dose of Yuvafem, take it again as soon as possible. However, if the time you remember is close to the due time for your next dose, skip the missed dose and continue taking it as scheduled. Absolutely do not double the dose of the drug more than the treatment regimen. Overdosing on Yuvafem can cause serious symptoms such as nausea, severe vomiting, abnormal vaginal bleeding,...

Drug interactions can reduce the effect of Yuvafem, or increase the effect of unwanted effects. Tell your doctor about all other medications you are taking including over-the-counter, prescription, vitamins, and herbal products. Do not stop, start, or change the dose of any medicine without your doctor's approval without your doctor's approval.
Some drugs that may interact with Yuvafem include:
Aromatase inhibitors: anastrozole, exemestane, letrozole Fulvestrant Ospemifene Raloxifene Tamoxifen Toremifene Tranexamic acid In addition, Yuvafem may interfere with certain laboratory tests. test and lead to erroneous results. Make sure that the medical staff and doctors know that you are using Yuvafem .

Store Yuvafem at room temperature, away from light and away from moisture. Do not store Yuvafem in a humid place or in the freezer. Different medicines will have different storage methods, so read carefully the storage instructions for Yuvafem on the packaging, or ask your pharmacist. Keep Yuvafem out of the reach of children and family pets. When the medicine is no longer usable or has expired, dispose of it according to the correct procedure. Do not arbitrarily dispose of Yuvafem into an environment such as a water pipe or toilet unless requested. Please consult your waste disposal company or pharmacist on how to safely dispose of Yuvafem to help protect the environment. In short, Yuvafem is a form of estrogen hormone used by women, which works to improve menopausal vaginal symptoms such as vaginal dryness, burning, and itching. However, Yuvafem can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of side effects and increase effectiveness. for the treatment.

Reference source: webmd.com