Berberine is widely used to treat gastrointestinal diseases such as colitis, dysentery, jaundice hepatitis, and conjunctivitis-related eye pain, as well as some skin conditions like athlete's foot, itching caused by fungal infections, etc. Globally, there are studies on other effects of berberine, including lowering blood sugar, reducing cholesterol, aiding weight loss, and supporting cancer treatment.

Senna tea is a popular herbal medicine often marketed as a laxative, weight loss aid, and detoxifying agent. However, there is limited scientific evidence to support most of these uses—apart from its effectiveness in treating constipation.