Dengue fever is primarily characterized by fever and bleeding. Bleeding manifestations in dengue can include nosebleeds, bleeding gums, subcutaneous bruising, gastrointestinal bleeding, vaginal bleeding. In severe cases, it can cause red blood cell rupture, vascular leakage, blood concentration, and massive internal and external bleeding, which can be fatal.

Treatment of dengue fever requires timely and proper rehydration and electrolyte repletion to limit serious consequences caused by dehydration, such as shock, circulatory collapse, coma, and neurological disorders.