Polycystic ovary syndrome and its association with hypertensive disorders of pregnancy

The article was written by MSc Vu Duy Thai - Obstetrician and Gynecologist, Women's Health Center - Vinmec Times City International General Hospital.

Polycystic ovarian syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age.

PCOS has a complex effect on fertility (menstrual cycle disorders, infertility, pregnancy complications...), metabolism (insulin resistance, metabolic syndrome, diabetes, other factors) cardiovascular risk factors...) and psychological (anxiety, depression...).
Regarding pregnancy, many large studies have shown PCOS to be a major risk factor for many adverse outcomes. In addition to increasing the rate of miscarriage, premature birth, gestational diabetes, perinatal mortality..., hypertensive disorders in pregnancy, especially the increased rate of pre-eclampsia are also important factors. proven bad outcomes.
2. Effect of PCOS on hypertensive disorders in pregnancy Large studies have shown that pregnancy in women with PCOS has an increased incidence of gestational hypertension (including gestational hypertension, preeclampsia, eclampsia). Research results show that the risk of developing gestational hypertension in women with PCOS is 3.7 times higher than in women without PCOS, the risk of preeclampsia is also nearly 3.5 times higher. .

Due to the increased risk of preeclampsia and hypertensive disorders in women with PCOS. Therefore, pregnant women with PCOS should be screened for preeclampsia in the first trimester of pregnancy.
Regarding prevention, given the mechanism by which PCOS affects preeclampsia, weight loss may play an important role. According to the results of a number of studies, lifestyle adjustments (a reasonable diet and exercise regimen) have been shown to help reduce the risk of preeclampsia in overweight and obese pregnant women.
In addition, the role of Metformin in the prevention of preeclampsia and hypertensive disorders of pregnancy is also mentioned.
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