Uses of Cefapezone

Cefapezone is an antibiotic of the 3rd generation cephalosporin group. The main ingredient is Cefoperazone 1g used to treat infectious diseases, severe infections. Cefapezone is a brand name drug, so it can only be sold and used when prescribed by a qualified doctor. In addition, the drug's pharmacological properties are very strong, so patients need to take the drug under the supervision of medical staff.

Cefapezone is a brand name drug belonging to the group of antibiotics, anti-inflammatory and antifungal drugs.
Drug information:
Preparation: powder for injection Packing: Box x 1 vial, box x 10 vials Drug ingredients:
Main active ingredient: Cefoperazone content of 1g Other excipients

Cefapezone is an antibiotic with the main ingredient being Cefoperazone - a drug with bactericidal effect by its ability to inhibit bacterial cells that are growing and dividing into cell wall synthesis. As a result, Cefapezone is indicated for use in cases including:
Treatment of severe infections caused by susceptible Gram (-), Gram (+) bacteria and bacteria that are resistant to beta antibiotics - other lactams. Treatment of infections of the upper respiratory tract, lower respiratory tract, biliary tract, skin and soft tissue infections, osteoarthritis, urinary tract infections, pelvic inflammatory disease, gynecological infections, intra-abdominal infections, .... Effective replacement of Penicillin for the treatment of infections caused by Pseudomonas bacteria in patients who are sensitive to Penicillin-containing drugs. In particular, if Cefoperazone is used to treat infections caused by Pseudomonas bacteria, it should be combined with Aminoglycosides to quickly achieve effectiveness and shorten treatment time.

Some cases where the use of Cefapezone is not recommended:
Patients with hypersensitivity or hypersensitivity to the formula ingredients in the drug. Elderly patients, debilitated body.

How to use:
Cefapezone is in powder form, used by dilution with solution for direct injection into the muscle or vein. This is a brand name drug, it should be administered and supervised by qualified medical staff and fully equipped with first aid facilities.
Dosage: Cefapezone is a prescription drug, so in each specific case, a specialist doctor will have an appropriate dosage indication. In addition, patients can also refer to the dosage below:
Adults:
Treatment of mild to moderate infections: 1-2 g/time, 1 injection every 12 hours. Severe to very severe infections: up to 12g/day (24 hours), divided equally into 2-4 injections. Liver disease or biliary obstruction: Not more than 4g/day (24 hours). Renal impairment: The maximum dose should not exceed 4g/day, but if there are signs of drug accumulation, the dose must be reduced to adjust. Concomitant hepatic and renal failure: Not more than 2g/day (24 hours). If in the case of high doses, it is necessary to monitor the concentration of Cefoperazone in the blood plasma regularly to adjust accordingly... People on hemodialysis treatment: Need a separate regimen after hemodialysis. Newborns and young children: 25-100mg/kg body weight, 12 hours after injection again. Because of the strong medicinal properties of the drug, the patient needs to take the correct dose in the prescription, do not arbitrarily increase or decrease the dose without special instructions from the doctor.

Almost all anti-inflammatory and anti-infective drugs have the potential to come with unwanted side effects. Each location will experience different conditions such as:
Common: Diarrhea, skin rash Uncommon: Mild fever, itching urticaria, temporary pain at the site of intramuscular or intravenous injection, neutropenia toxicity, thrombocytopenia... Rare: Convulsions, delirium, headache, pseudomembranous colitis, vomiting, nausea, cholestatic jaundice, anaphylaxis, interstitial nephritis, candidiasis, arthralgia ,... Usually these side effects will go away on their own after a few days when the body has responded to the drug, but the patient is not so subjective, please actively monitor your health, if any abnormalities are detected. Please contact the nearest medical facility immediately for the appropriate treatment plan.

Drug interactions when used are inevitable when taking any medicine, not just Cefapezone. Therefore, patients should pay attention to avoid interactions, do not use Cefapezone with some of the following drugs or foods:
Alcohol, alcohol-containing substances: If drinking alcohol 72 hours after taking Cefoperazone, there are can cause symptoms such as flushing, sweating, nausea, headache, arrhythmia (this is called a disulfiram-like reaction). Aminoglycosides: Concomitant use may increase the risk of nephrotoxicity. In addition, to ensure safety and avoid unwanted interactions, it is best for patients to provide information about strange drugs or foods to their doctors for appropriate instructions.

Some important notes patients need to know are:
Use the right dose, at the right time. Do not arbitrarily inject drugs at home or ask non-medical professionals to perform injections. The drug ingredients do not affect traffic activities, production operations,... Although the drug has been studied in reproductive rats, no abnormalities have been found with fetal morphology, However, there are no studies on humans, so pregnant women should only use it when necessary and consult a doctor. The amount of drug excreted in breast milk is relatively low, so nursing mothers can still use it normally, but it is necessary to monitor the baby for abnormal reactions.

Overdose: Usually Cefapezone is injected by medical staff, so the possibility of overdose is very rare, but if there is an overdose situation, the patient should be treated as follows:
If symptoms of convulsions appear, increase Neuromuscular stimulator immediately informs physician to proceed with respiratory protection by supporting ventilation and perfusion, using anticonvulsant therapy. Then, hemodialysis to remove excess drug. Note that currently there is no specific treatment but only supportive measures to treat symptoms.
Missed dose: Otherwise, if you miss a dose, immediately notify the medical staff for additional injection. However, if it is too close to the next dose, it is possible to forget the dose and take the next dose as scheduled. Do not arbitrarily increase the dose.
Cefapezone is an antibiotic of the 3rd generation cephalosporin group. The main ingredient is Cefoperazone 1g used to treat infectious diseases, severe infections. Cefapezone is a brand name drug, so it can only be sold and used when prescribed by a qualified doctor. In addition, the drug's pharmacological properties are very strong, so patients need to take the drug under the supervision of medical staff.