Uses of Letristan

Letristan is effective in the treatment of acute sinusitis, bronchitis, pneumonia, prostatitis, urinary tract infections, skin infections. Letristan is a prescription drug, to ensure its effectiveness when used, patients need to follow the instructions of a specialist, and refer to more information about the use of the drug in the article below.

1.1. What is Letristan? Letristan belongs to the group of antiparasitic, anti-infective and anti-viral, anti-fungal drugs. Has registration number VN-16677-13, Made by M/s Bio Labs (Pvt) Ltd – Pakistan, and registered by DOHA Pharmaceutical Co., Ltd.
Prepared in the form of: Film-coated tablets. Box has 1 blister x 10 tablets each. Letristan contains the main ingredient Levofloxacin (as Levofloxacin hemihydrate) 500mg of other active ingredients. 1.2. What does Letristan do? Levofloxacin is a derivative of Quinolone Levofloxacin, it has a broad spectrum of activity against many strains of bacteria such as staphylococcus or streptococcus, pneumococcus. Letristan 500mg medicine is used in the treatment of mild or moderate infections such as: exacerbation of chronic bronchitis, pneumonia, community-acquired pneumonia or acute sinusitis, skin - skin structure infections, urinary tract infections urology with or without complications, acute pyelonephritis. Contraindications:
People with hypersensitivity to ingredients or excipients in the drug. The patient has epilepsy. The patient has a history of tendon pain associated with the use of fluoroquinolones. Children under the age of 18.

2.1. How to take Letristan Letristan is used orally, after meals. Should take the whole pill with about 30 - 50ml of filtered water, do not take the drug with carbonated water, milk or tea because it can change the quality of the drug. If the tablet is too large to swallow, it can be broken in half but must not be crushed, broken or mixed with other mixtures. Letristan should be taken at least 2 hours before or after taking preparations containing salt, zinc, antacid, aluminum. Adhere to the correct course of use in terms of dosage and duration of medication. Do not arbitrarily add or decrease the dose other than prescribed by your doctor. 2.2. Dosage of Letristan Treatment in acute sinusitis : 500mg daily, for 10 to 14 days. Chronic bronchitis: 250 - 500mg daily, for 7 to 10 days. Community-acquired pneumonia: 500 mg once or twice a day, for 7 to 14 days. Urinary tract infections: 250mg per day, for 7 to 10 days. Skin and soft tissue infections: 500mg daily for 7 to 14 days. Patients with renal impairment (ClCr less than 50mL/min): Reduce dose. Community-acquired pneumonia: 500mg/time, 1 to 2 times/day for 7 to 14 days. Prostatitis: 500mg/day Pyelonephritis: 500mg/time/day for 7 to 10 days. Chronic bacterial prostatitis: 500mg/time/day for 28 days. Complicated skin and soft tissue infections: 500mg/time x 1 to 2 times/day, for 7 to 14 days. Acute bacterial sinusitis: 500mg/time/day for 10 to 14 days. Chronic bronchitis 500mg/time/day, for 7 to 10 days. Urinary tract infections, uncomplicated: 250mg/time/day for 3 days. Treatment when missed dose:
Usually drugs, can be taken within 1 to 2 hours than prescribed in the prescription. Unless it is a drug with very strict regulations on the time taken, the patient can take the medicine a few hours after the missed dose is discovered. However, if the time is very close to when you need to take the next dose, you should not take it because it can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before the patient decides to supplement the missed dose. Treatment in case of overdose:
If the patient overdoses on Letristan and has unusual symptoms, it is necessary to immediately notify the doctor or the person in charge. In case of overdose of Letristan and abnormal symptoms, the patient needs emergency treatment for appropriate diagnosis and treatment.

Letristan 500mg should be used with caution in patients with convulsions, G6PD deficiency and a history of cardiovascular, renal or severe liver failure. Prolonged use of Letristan may lead to overgrowth of non-susceptible microorganisms and possible superinfection. Letristan treatment interferes with false-positive urinalysis and opiate tests. Carefully read the information on the leaflet before the patient takes the medicine. If adverse reactions occur while using Letristan, the drug should be discontinued and appropriate symptomatic measures taken. In patients with a convulsive nature, for example in the case of co-administration of many drugs and other quinolones, great caution should be exercised when using Letristan. Diarrhea, especially in people with severe, persistent or bloody diarrhea during and after treatment with Letristan, may be a symptom of Clostridium difficile pseudomembranous colitis. If pseudomembranous colitis is suspected, the patient should immediately stop taking the drug. Tendinitis, which can sometimes lead to tendon rupture, especially of the Achilles tendon (Achilles tendon) may occur with this medicine. In patients with renal impairment, the dose of Letristan must be adjusted because it is excreted mainly by the kidneys. Patients with latent glucose-6-phosphate dehydrogenase enzyme deficiency or predisposition to hemolytic reactions during treatment with quinolone antibacterial agents. Letristan 500mg medicine may cause side effects such as headache or dizziness, drowsiness and visual disturbances,... Therefore, drivers and operators of machines should not use this medicine. Currently, there is not enough evidence to prove the safety of Letristan during pregnancy. Therefore, patients need to carefully weigh the benefits and toxicity of Letristan, and should consult with their doctor before using. The drug is distributed in breast milk, causing the risk of cartilage degeneration in children, so Letristan should not be used by nursing mothers.

Nausea or vomiting, diarrhea, taste changes, sleep disturbances, headaches and dizziness. Uncommon: Leukopenia, loss of appetite, anxiety and taste disturbances, shortness of breath or rash,... Rare: Abdominal pain, changes in vision, photosensitivity or allergic reactions inflammation, pain, swelling of joints-muscle-tendons. Very rare: Restlessness, anxiety, seizures or mental disorders, chest pain and cardiac arrhythmias, changes in urine output, yellow eyes, jaundice, superinfection with prolonged use.

Letristan drug contains Levofloxacin, which causes interactions with diabetes drugs, non-steroidal anti-inflammatory drugs (NSAIDs); Theophylline; Antacids containing Mg/Al; sucralfate; metal cations and preparations containing many vitamins. Medicines containing Iron or zinc, antacids and magnesium,... reduce the absorption of the drug Letristan 500. Anticoagulants increase the risk of bleeding. Hypoglycemic drugs increase the risk of dysglycemia. Theophylline and NSAIDs can cause seizures. Probenecid, Cimetidine may interfere with the tubular secretion of Letristan. Antiarrhythmic drugs or antidepressants, macrolide antibiotics affect the heart rhythm.

Letristan storage time is 36 months from the date of manufacture. Store Letristan in a cool, dry place, at a temperature not exceeding 30°C, in its original packaging and out of direct sunlight. You should not store Letristan in the bathroom or the freezer compartment of the refrigerator. Keep out of reach of small children and pets. Before taking the drug Letristan should carefully check the expiry date of the drug. Absolutely do not use Letristan after the expiry date printed on the package. Dispose of medication properly when it is expired or cannot be used. You should consult your pharmacist or local waste disposal company about how to safely dispose of your medication. Above is all information about Letristan, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Letristan is a prescription drug, you need to use it as prescribed by your doctor, absolutely do not self-treat at home.