Efficacy of IUI in infertility treatment: questions about intrauterine insemination (IUI)

The article is written by MSc, BS. Nguyen Thi Nhu Trang - Reproductive Support Center - Vinmec Times City International General Hospital. The doctor has strengths and experience in performing specialized techniques in the IVF Lab such as ICSI, biopsies for preimplantation genetic diagnosis, thawing embryos, oocytes...

For men:
Ejaculation disorders such as low urinary tract, retrograde ejaculation, erectile dysfunction. Poor sperm quality: Low sperm count, poor motility, high percentage of malformed sperm. Combination of the above cases but at a mild level. Anti-sperm antibodies in men or women. For female
Case of irregular ovulation. Mild and moderate endometriosis. Infertility of unknown cause. Wife is allergic to semen or sexually transmitted diseases, such as HIV or hepatitis B.

The IUI process starts from the first day of the menstrual period until ovulation, usually takes about 10-14 days, and the results of conception are checked two weeks later.
The process of IUI treatment usually goes like this:
Day 2 or day 3 of the cycle, the wife is given ovarian stimulation drugs. On 6-7 menstrual cycles, the wife goes to an ultrasound to assess the response status of the ovaries, through which the doctor adjusts the medicine and makes an appointment for the next ultrasound. Around day 9 - 10, if there is a "ripe" follicle, the wife is injected with ovulation medicine. At the same time, the husband was assigned to collect semen to conduct filtration and select good motile sperm. On the day of pumping, couples will be scheduled to come 2 hours before the injection because the time of sperm washing will take about 1 - 1.5 hours After 36 - 40 hours after the injection of ovulation medicine, the sperm injection the wife's uterus is conducted. This procedure is usually painless 2 weeks later, the wife goes to the hospital to check the results. Thus, in favorable cases, it takes about 25-30 days from starting the process of artificial insemination with IUI to knowing the results of pregnancy or not.

The success rate of IUI depends on a couple's fertility problems and age. Several studies have shown that for couples with unexplained infertility, the success rate of conception for each spontaneous IUI cycle is about 7 to 10 percent, and when fertility drugs are used. , this rate increases from 15 to 20%.

For many couples, IUI is the first choice of treatment because it is less invasive and less expensive than other assisted reproductive technology treatments such as in vitro fertilization (IUI). IVF). For couples who have problems with their husband's fertility, it is easier to conceive through IUI than through natural intercourse. Couples with unexplained infertility often have better outcomes using IUI than using fertility drugs alone. The IUI procedure allows fertilization to happen naturally inside a woman's body.

Inconvenience: To perform sperm injection, the husband must go directly to the hospital to collect sperm. Must go back to visit regularly: Before and after sperm injection, the wife needs to go to the hospital for regular check-ups, tests and monitoring. Multiple pregnancy: IUI can make a woman pregnant with multiples, from 2 to 5 depending on the number of eggs released. Therefore, being pregnant with multiples still has potential risks, even affecting the health of both mother and baby. OHSS syndrome: Ovarian hyperstimulation syndrome for ovulation-stimulating drugs. Make the wife have pain in the abdomen, discomfort, nausea, fatigue, ...

The cost of IUI treatment will depend on the fertility problem the couple is having and the method you choose. Different rates may apply for each treatment facility. You should contact the place where you plan to have the IUI for details.

Vinmec IVF Reproductive Support Unit - Vinmec International General Hospital has technical support from many other departments such as the Research Institute of Stem Cells and Gene Technology, the Pediatric Center, the Department of Obstetrics and Gynecology, etc. constantly updating and developing new techniques in infertility treatment.
In addition to advanced reproductive support methods, a team of good doctors in the country and the world, with prestige and long experience in the field of infertility have a decisive role in the success of IVF Vinmec: TS.BS To Minh Huong - Center Director (Former Deputy Director of Hanoi Obstetrics and Gynecology Hospital), MSc - Dr. Le Thi Phuong Lan (Former Deputy Director of National Reproductive Support Center), Doctor Jean Clément Sage - Expert with 30 years experience in assisted reproduction in France.
If you need more advice on reproductive health and your own case at the Reproductive Center in Vinmec, do not hesitate to come directly to the consultation or book an appointment at the Website for service.

Reference source: babycenter.com