Uses of Agimycob

Manufacturer: Agimexpharm Pharmaceutical Joint Stock Company - Vietnam.
Packing: Box of 1 blister x 10 tablets.
Dosage form: Vaginal tablets.
Ingredients:
Metronidazole 500mg. Nystatin 100000IU. Neomycin 65000 IU. Excipients: Menthol, Lactose, Povidon, Magnesium stearate, Sodium lauryl sulfate, Sodium starch glycolate, Microcrystalline cellulose and corn starch just enough for 1 tablet.

Effect of the main ingredients in the formula
Metronidazol: is an antibacterial drug of the 5-Nitroimidazole group, capable of killing Gram-negative anaerobes, Trichomonas vagin alis and Giardia by destroying the structure. DNA helix of bacteria or protozoa. Neomycin: used to treat vaginitis or other bacterial infections. Nystatin: destroys Candida albican fungus, treats fungal infections on the skin mucosa. 2.1 Indications Candida albican or yeast infections in the vagina. Gardnerella vaginalis infection or Trichomonas vaginalis infection in the urogenital tract. Common purulent bacterial infections of the vagina. Vaginitis has no known cause or can be caused by a combination of factors. 2.2 How to use - Dosage of Agimycob How to use : Vaginal.
How to put:
+ Clean the vagina and hands with physiological saline or a low pH feminine hygiene solution before placing the medicine.
+ Dip the tablet in water for 20-30 seconds before placing it for easy use.
+ Keep the person in the supine position, can put an extra pillow behind the back.
+ Clamp the pill with your index and middle fingers, then slowly insert it into the vagina, putting it as deep as possible.
+ Lie still for about 15 minutes before getting up or exercising so that the medicine is absorbed into the body.
+ Clean hands after placing the medicine.
Dosage:
Refer to the dose as follows:
Use for 10 consecutive days, 1 tablet per day or can be increased to 2 tablets if really needed. When the disease does not improve, it is necessary to immediately report to the doctor for timely treatment. How to handle missed dose, overdose
When missed dose:
+ Take that dose as soon as you remember.
+ Skip the missed dose if it is almost time for the next dose, take the next dose as scheduled.
+ Do not double the dose.
In case of overdose:
+ Symptoms: No symptoms of overdose have been reported. However, with 12g orally, it can cause vomiting, ataxia, disorientation.
+ If you accidentally overdose and have serious side effects, immediately go to the medical center for timely treatment.

When using the drug for a long time, it is common:
+ Decreased white blood cells
+ Pancreatitis.
+ Peripheral nervous system affected.
Rare:
+ Urine is reddish brown.
+ Dry mouth, dizziness, dizziness.
+ Skin and mucous membrane allergies, urticaria, flushing.
+ Tongue inflammation.
Very rare:
+ Anorexia, abdominal distension, dyspepsia.
+ Diarrhea.
+ Nausea, vomiting, metallic taste in mouth.
+Local irritation reaction in the first few days of use.
+ If any side effects persist or worsen, you should notify your doctor.
Contraindications
AgiMycob is not used in the following cases:
Hypersensitivity to any ingredient in the formula. Pregnant. Patients with liver-related diseases, kidney, hematological disorders.

Possible drug interactions when taking drugs:
Spermicide: Reduces the effect of spermicides, leading to a high risk of unwanted pregnancy. Disulfiram : May lead to manifestations such as confusion, memory impairment, confusion. Alcohol: Concomitant use increases the risk of heart palpitations, vomiting, flushing, hot flushes. Some antibiotics can affect the effectiveness of treatment such as Fluoroquinolone, Macrolid, Cephalosporin.

Precautions for use:
Related to metronidazole
Treatment with metronidazole should not be prescribed for more than 10 days and not repeated more than 2-3 times a year. Discontinue treatment in case of local intolerance or allergic reactions or signs such as dizziness, confusion, ataxia appear. Caution should be exercised for neurological aggravation in patients with severe, chronic, or progressive CNS or peripheral neuropathy. It is necessary to limit the use of alcoholic beverages during treatment (Antabuse effect). Control of white blood cell counts in patients with a history of hematologic disorders, on high-dose or long-term therapy. Metronidazole can immobilize treponema pallidum resulting in a false-positive response to the Nelson test. Relating to neomycin
Sensitization to topical antibiotics may possibly affect future co-administration with antibiotics or other antibiotics of the same class. The duration of treatment should be limited due to the risk of selective bacterial resistance and superinfection caused by these organisms. Concerning lactose
This medicine contains lactose. Patients with rare hereditary problems of metabolism and galactose intolerance, the lactase lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Use on pregnant women and lactating mothers
Pregnant women : Neomycin contains the risk of entering the bloodstream and causing ear toxicity. It is forbidden to use the product for pregnant women.
Lactating mothers : There are no specific and detailed reports on whether the drug passes into breast milk or not, so use caution when administering this drug to this population.
People who drive and operate machinery
The drug can cause dizziness and lightheadedness, so care should be taken when driving a car and operating machinery.
Other special note
During the use of the drug should not have sex. Do not use the drug for more than 10 days. The drug contains Lactose, be careful with patients who are allergic to Lactose. Storage:
Temperature in the range of 20-25 degrees Celsius, in the refrigerator compartment. The humidity of the storage place should be less than 70%. Avoid direct light. Keep out of sight and reach of children. Do not use after the expiry date printed on the package and do not put the medicine in the toilet, sink or drain.