Uses of Cilaprim

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Cilaprim is used intramuscularly or intravenously to treat infections. To use Cilaprim effectively and to overcome the disease early, you should strictly follow the treatment regimen previously suggested by your doctor.

1. What is Cilaprim?

Cilaprim is an antibiotic used in cases of bacterial infections. The drug is prepared as a powder for injection with a combination of 2 main active ingredients, including Imipenem (500mg) and Cilastatin (500mg). In addition, the drug Cilaprim also has the presence of other auxiliary excipients that have been added by the manufacturer for the purpose of enhancing the therapeutic effect.
Cilaprim is currently researched, developed and manufactured by Makcur Laboratories Ltd - India. According to experts, the combination of the active ingredients Cilastatin and Imipenem in the same formula helps to quickly reverse respiratory, skin, gynecological, genital, and respiratory infections. urine,...

2. What does Cilaprim do?

The active ingredient Imipenem in Cilaprim acts as an antibiotic belonging to the Carbapenem group, capable of effectively killing pathogenic bacteria through blocking the synthesis of bacterial cell walls. In general, the spectrum of action of Imipenem is relatively broad, including Gram-negative, Gram-positive, anaerobic bacteria and especially blue bacilli.
Not only that, Imipenem is also effective against all strains of Beta lactamse, except Metallo - Beta lactamase. However, the antibiotic activity of Imipenem may be adversely affected by the action of dehydropeptidase in the renal tubules. Therefore, Imipenem is often combined with Cilastatin to prevent this destruction.

3. Indications – Contraindications to using Cilaprim

According to the doctor's recommendation, Cilaprim is used to treat the following infections:
Lower respiratory tract infections. Abdominal infection. Gynecological infections. Urinary tract infections . Genital tract infection. Musculoskeletal infections. Skin and soft tissue infections. Sepsis . Endocarditis. However, it is necessary to avoid self-treatment with Cilaprim for the following patients without consulting a doctor:
People who are allergic or have hypersensitivity reactions to Imipenem, Cilastatin, Carbapenem antibiotics or any other any excipients in the formulation. Cilaprim is contraindicated in pediatric patients under 3 months of age. Relative contraindications Cilaprim for pregnant women or nursing mothers.

4. Instructions for using Cilaprim correctly

Cilaprim is used by intramuscular or intravenous route, depending on the doctor's prescription. Dosage of Cilaprim will be calculated based on the active ingredient Imipenem, specifically:
Treatment of infections caused by susceptible bacteria in adults: Intravenous infusion from 1-2g/day, divided into 3-4 times/day. May be IV infusion up to a maximum dose of 4g/day or 50mg/kg body weight/day. Treatment of bacterial infections for children > 3 months old: Use a dose of 60mg/kg body weight/day, up to 2g/day and divided into 4 times. For children > 40kg can use the same dose as adults. Children under 40kg can be given a dose of 15mg/kg body weight every 6 hours. Prophylaxis of infection: Administer 1000 mg intravenously at the start of anesthesia and continue at 1000 mg 3 hours later. Dosage for patients with renal failure: Do not use more than 2g/day. During treatment with Cilaprim, patients need to strictly follow the doctor's treatment regimen. Absolutely do not arbitrarily apply, change the dose or duration of treatment without discussing with the doctor.

5. What side effects does Cilaprim cause?

In addition to the effective treatment of infections, Cilaprim can cause some adverse reactions for patients in certain cases:
Painful swelling or thrombophlebitis at the injection site. Hives, itching, or rash on the skin. Gastrointestinal reactions such as pseudomembranous colitis, diarrhea, nausea or vomiting. Convulsions (rare). Psychosis. Increase liver enzymes. Erythema or hematologic disorder. Taste disorder. Psychosis . Confusion state. If any of the side effects mentioned above occur, the patient should promptly notify the doctor for appropriate treatment. Some symptoms may go away when treatment is stopped, but in some cases, an adverse reaction caused by Cilaprim has the potential to progress to another serious problem.

6. What precautions should be taken while using Cilaprim?

When treated with Cilaprim, patients should be cautious of the following general recommendations:
Cilaprim should be used with caution in patients with a history of partial cross-allergy to some other beta-lactam antibiotics. or digestive disorders. During the use of Cilaprim, if any CNS symptoms occur, the patient should reduce the dose or discontinue the treatment. Read the instructions carefully to know how to properly store the medicine, especially after making the injection. If you notice that the medicine has an unusual change in color, you absolutely do not use and handle the damaged medicine as recommended. Cilaprim has the potential to interact with other medications, including dietary supplements, supplements, vitamins or herbs. Therefore, patients should inform their doctor about all medications they are currently taking to avoid the risk of drug interactions. The basic information about Cilaprim in the above article is for reference only. Because Cilaprim is a prescription drug, patients should not use it on their own, but need to contact a doctor/pharmacist directly to get an appropriate prescription and ensure safety for health.

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