Uses of Citicoline

Oral citicoline is effective in the treatment of Alzheimer's disease, dementia due to multiple infarcts, traumatic brain injury, cerebrovascular accident, Parkinson's disease and tardive dyskinesia. To better understand the drug, please refer to the following article about ingredients, uses, indications and notes when using Citicoline.

Citicoline drug has the main ingredient is Citicoline, the drug has the effect of stimulating biosynthesis of phospholipids on nerve cell membranes, helping to fight brain damage, enhancing neurotransmitter function. The drug increases blood perfusion to the brain, increasing brain oxygen consumption through the following mechanisms:
Citicoline acts as a precursor in the biosynthesis of phospholipids on neuronal membranes. Under the catalysis of the enzyme choline phosphotransferase, citicoline will combine with diacylglycerol to form phosphatidylcholine. Exogenous citicoline contributes significantly to the choline storage system, which is essential for the brain's synthesis of acetylcholine. Citicoline enhances neurotransmitter function through increased release of norepinephrine, dopamine, and serotonin. 1.1. Citicoline is indicated in the following cases:
Patients with acute encephalopathy including: Acute and subacute cerebrovascular accident such as cerebral circulatory insufficiency, cerebral hemorrhage, cerebral palsy. Traumatic brain injury . Patients with chronic encephalopathy include: senile degeneration including Alzheimer's disease, primary degenerative dementia, multifocal infarct dementia, sequelae of cerebrovascular accident, traumatic brain injury ... 1.2. Contraindications to the drug Citicoline Citicoline is contraindicated in the following cases:
Patients with hypersensitivity to drug components. Increased tone of the parasympathetic nervous system.

2.1. Dosage Before using any medicine, patients should consult a doctor to get good results and avoid unwanted cases.
Citicoline drug has the following forms and strengths:
Infusion: citicoline 500 mg/2 mL, 250 mg/mL Syrup, oral medication: citicoline 500 mg/5 mL, 100 mg/mL Tablets, oral medication: 500 mg , 1g. Dosage of Citicoline for adults
Oral drugs for patients with cerebrovascular disorders, cognitive disorders, Parkinson's or head trauma: oral citicoline 500mg x 2 times/day or 1g tablet taken as a single dose a day; Oral solution used from 100-200mg x 2 times / day. Infusion drugs used for patients with venous cerebrovascular disorders, acute phase in traumatic brain injury with mental disturbances, Parkinson's disease, cognitive disorders: the average dose is citicoline 500mg - 1000mg/ 24h intramuscular or slow intravenous injection over 3-5 minutes; or intravenous infusion at a rate of 40-60 drops/min. In general, intravenous administration is preferred over intramuscular injection. If patients with traumatic brain injury have sudden and persistent intracranial bleeding, only a maximum intravenous infusion of 1000mg/24h, the rate of 30 drops/min. Dosage of citicoline for children
Children use oral solution with a dose of 100mg x 2-3 times/day. The maximum duration of treatment is from 9 to 12 months. The doses above are the manufacturer's recommendations, the doctor may change depending on the medical condition of each person. 2.2. How to take Citicoline Oral Citicoline is taken with food or between meals. The oral solution can be used directly or mixed with 120ml of water. Citicoline infusion is only used under the guidance, adjustment and monitoring of medical staff, not arbitrarily used at home. Dosage is based on your medical condition and response to treatment. Do not arbitrarily stop, take more medicine or more often than prescribed by your doctor.

Before taking citicoline you should:
Tell your doctor if you are allergic to citicoline, acetylsalicylic acid or any other drugs If you have fructose intolerance, talk to your doctor. Tell your doctor about any medications you are taking, including herbs and supplements. Pregnancy and breast-feeding should not be used Citicoline is contraindicated in patients with increased parasympathetic nerve tone, cautiously reduce the dose if intracranial bleeding persists.

4.1. Interaction of Citicoline with drugs Citicoline may change the activity of L-Dopa, so it should not be used with drugs containing meclofenoxate. To avoid drug interactions, it is best to keep a record of all the medications you are taking and consult your doctor before taking. Although some drugs should not be used together, in some cases they can be used together. taking two drugs together even if an interaction occurs. In these cases, your doctor will change the dosage or take other precautions. 4.2. Interactions of Citicoline with food and beverages Limit the use of alcohol and tobacco because these items can reduce the drug's effects and affect the body's health.
In summary, the drug Citicoline is effective in treating Alzheimer's disease, memory loss and related problems. The use of medication to treat the disease should be done according to the doctor's prescription for the best treatment results.