Uses of Mealphin 7.5

Mealphin 7.5 drug containing the active ingredient Meloxicam is indicated in the treatment of pain relief and anti-inflammatory diseases of bones and joints such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis... Let's learn about the uses, the Note when using Mealphin 7.5 through the article below.

Mealphin 7.5 is prepared in the form of tablets containing the active ingredient Meloxicam.
Active ingredient Meloxicam belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Meloxicam's anti-inflammatory activity is strong on all types of inflammation, acting by inhibiting the synthesis of Prostaglandin - inflammatory mediators. Meloxicam has a stronger selective effect on COX-2, which reduces the majority of gastrointestinal side effects.
Mealphin 7.5 is indicated in the following cases:
Osteoarthritis, degenerative joint disease, joint disease; Rheumatoid arthritis ; Ankylosing spondylitis .

Dosage of Mealphin is prescribed by the treating doctor based on the patient's condition and tolerability. Some recommendations on the dosage of Mealphin 7.5 are as follows:
Treatment of osteoarthritis: Take 7.5mg/day, the dose can be increased to 15mg/day if necessary; Treatment of rheumatoid arthritis: Oral 15mg/day, dose should be reduced after 1 dose of active treatment; Ankylosing spondylitis: Oral 15mg/day, dose should be reduced after 1 dose of active treatment; The starting dose of Mealphin in patients at increased risk of adverse reactions is 7.5 mg/day; Drug dose in hemodialysis patients should not exceed 7.5mg/day; The recommended dose in children 12 years of age and older is 0.25 mg/kg body weight. The duration of treatment with Mealphin 7.5mg should be as short as possible with the lowest effective dose.

Mealphin 7.5 can cause some side effects as follows:
On the respiratory system: Causes asthma attacks in patients who are sensitive to Acetylsalicylic Acid or other NSAIDs; Gastrointestinal: Nausea, vomiting, dyspepsia, constipation, stomatitis, esophagitis, latent or stable gastrointestinal bleeding, transient changes in liver function parameters (transaminase elevations), colitis colon , hepatitis, intestinal perforation; On the central nervous system: Tinnitus, dizziness, drowsiness, excitability, nervous disorders, disorientation; On the organ of vision: Conjunctivitis , visual dysfunction; On the cardiovascular system: Palpitations, increased cardiac pressure, flushing; On the urinary system: Acute renal failure, acute urinary retention, changes in renal function index; On the skin system: Pruritus, rash, urticaria, photosensitivity, Stevens - Johnson syndrome, epidermal necrolysis; Angioedema, anaphylactic shock. Patients need to stop using Mealphin 7.5 and notify the treating doctor in case of any unwanted effects when using the drug.

4.1. Contraindications Contraindicated to use Mealphin 7.5 in the following cases:
Patients are allergic to Meloxicam or any component of Mealphin 7.5; Patients with bronchial asthma, angioedema, nasal polyps or urticaria caused by the use of Aspirin or any other NSAID; Patients with stomach ulcers - duodenum; People with colon diseases such as ulcerative colitis, Crohn's disease; Patients with renal failure without hemodialysis, severe liver failure; People with disorders causing bleeding disorders, gastrointestinal bleeding, recent cerebrovascular bleeding; Patients with uncontrolled heart failure; Children under 12 years old; Pregnant women; Women are breastfeeding. 4.2. Precautions for use Similar to other non-steroidal anti-inflammatory drugs, Mealphin 7.5 should be used with caution in patients with gastrointestinal disease or in patients receiving anticoagulant therapy. Discontinue use of Mealphin as soon as symptoms of peptic ulcer or gastrointestinal bleeding occur.
Meloxicam inhibits Prostaglandin biosynthesis, so it should be used with caution in elderly patients, chronic heart failure patients, dehydrated patients, nephrotic syndrome... For people with heart diseases , Meloxicam may increase the risk of developing serious cardiovascular diseases, heart attacks, strokes, blood clots which can be fatal... Meloxicam is to increase sodium, potassium, water retention and make change the sodium-secreting effect of diuretics. Therefore, the risk of hypertension or heart failure may occur or be aggravated in susceptible patients.
Be careful when using Mealphin 7.5 in patients with kidney failure, liver failure, the elderly, heart failure.

Concomitant use of Mealphin 7.5 with other NSAIDs increases the risk of undesirable effects, especially on the gastrointestinal tract such as gastric ulcer, gastrointestinal bleeding due to synergistic effects.
Meloxicam in combination with anticoagulants, heparin, thrombolytics, antiaggregants, selective serotonin reuptake inhibitors increases the risk of bleeding due to inhibition of platelet function.
Meloxicam reduces the excretion of Lithium in the kidneys, leading to increased levels of Lithium in the blood, increasing the risk of unwanted effects.
Mealphin 7.5 increases the unwanted effects of Methotrexate on the hematopoietic system, so patients need to periodically do a blood count.
Scientific studies show that Meloxicam reduces the effectiveness of IUDs.
Concomitant use of Meloxicam and Cholestyramine increases the elimination of Meloxicam.
The effectiveness of antihypertensive drugs such as ACE inhibitors, beta channel blockers... increases when used simultaneously with Meloxicam.
Concomitant use of Meloxicam and diuretics increases the risk of acute renal failure.
Nonsteroidal anti-inflammatory drugs and angiotensin II receptor antagonists act synergistically when used together, which may lead to acute renal failure in patients with a history of renal dysfunction.
Non-steroidal anti-inflammatory drugs affect renal prostaglandins, increasing nephrotoxicity. Therefore, close monitoring of renal function is required when the products are used concomitantly.
Drug interactions occur to reduce the therapeutic effect of Mealphin 7.5, increasing the risk of unwanted effects. Therefore, patients need to inform their doctors about the drugs and supplements they are using to ensure the safety and effectiveness of treatment with Mealphin 7.5.
Above is all the important information about Mealphin 7.5, in the process of using, if you have any problems, you can contact your doctor for specific advice.