Uses of Sacendol

Sacendol has the main ingredient Paracetamol, which is a medicine to treat flu symptoms, fever, runny nose as well as analgesic and anti-allergic effects. Let's learn about the uses, dosage and notes when using Sacendol through the following article.

Sacendol drug has the main ingredient Paracetamol 150mg, which is prepared in the form of nuggets.
Paracetamol or Acetaminophen, is a metabolite of Phenacetin. With the same dose as Aspirin, Paracetamol has effective antipyretic and analgesic effect. However, unlike aspirin or other NSAIDs, paracetamol is not effective in the treatment of inflammation.
Paracetamol's analgesic effect is achieved through a mechanism of reducing nociceptive signal transduction in the spinal cord by inhibiting central COX-2 activity and 5-hydroxytryptamine pathway activity.
Paracetamol acts on the thermoregulatory center in the brain, dilates blood vessels, increases peripheral blood flow to help radiate heat. Paracetamol has little effect on the cardiovascular, respiratory or the whole body. In addition, the drug does not increase bleeding or affect the stomach because it does not change the acid-base balance, does not irritate the stomach.

Sacendol is used for mild or moderate pain and fever. In addition, Sacendol also treats symptoms of sudden weather changes such as colds, rhinitis, sinusitis, runny nose, headache or toothache, abdominal pain,...
Sacendol is not used for Patients with the following conditions:
History of hypersensitivity to any drug containing Paracetamol. Inherited deficiency of the enzyme Glucose - 6 - Phosphate dehydrogenase. High fever over 39.5 degrees C. Anemia. Severe liver failure. Severe peptic ulcer disease. Prostate enlargement. To ensure safety when using Sacendol, patients need to inform their doctor or pharmacist of their medical condition and history of allergies so that the drug can be considered.

Sacendol is used orally. Dissolve the sachet in an appropriate amount of water, wait until the effervescence is gone and use immediately. Sacendol has a sweet taste and fruity aroma, so it is suitable for children. Sacendol can be taken with or after meals.
Dosage depends on the age of the child:
Children from 6 to 12 months old: 1/2 pack/time, 2 times a day. Children from 1-2 years old: 1 pack / time, 2 times a day. Children from 2 to 3 years old: 1 pack/time, 3-4 times a day. Children from 4-5 years old: 1.5 sachets/time, 3-4 times a day. Children from 6 to 8 years old: 2 packs/time, 3-4 times a day. Do not use Sacendol for children under 6 months of age. Parents need to give their children the right medicine and dosage according to the doctor's instructions. Do not arbitrarily use the drug or increase the dose.

When using Sacendol, patients may experience some unwanted side effects such as:
Common: Fever, mucosal lesions, skin rash, other allergic reactions, urticaria. Uncommon: pruritus, dyspnoea, nausea, vomiting, dysphagia, neutropenia, anemia, renal disease, hepatotoxicity if overdosed. Rare: hypersensitivity reactions such as swelling of the eyes, tongue, throat, ... If the patient experiences the above symptoms while using Sacendol, it is necessary to stop the drug and go to the nearest medical facility for appropriate treatment. .

For children with fever, parents or caregivers must regularly monitor the temperature with a thermometer and have traditional fever-reducing methods such as wearing breathable clothes, warm towels, and drinking plenty of water to support the child during the process. treatment course. Prolonged use of Paracetamol may lead to leukopenia, thrombocytopenia or total platelet count. Sacendol should be used with caution in patients with liver failure or impaired renal function. Sacendol should be used with caution in patients with a history of moderate or severe anemia, as it may cause clinically insignificant cyanosis when methemoglobin levels are already very high. Do not self-medicate with Sacendol for more than 10 days in adults or more than 5 days in children. Sacendol has little effect on the ability to drive and use machines, so patients can perform these activities during treatment. There are no adequate studies on the safety of Sacendol in pregnant women. Therefore, unless absolutely necessary, Sacendol should not be used by pregnant women. Currently, the extent of Paracetamol excretion into breast milk has not been officially recorded, however, there have been no adverse effects on infants when mothers use Paracetamol.

Sacendol may interact if used concurrently with the following drugs:
Concomitant use of Paracetamol with Coumarin or Indandion derivatives in analgesic and antipyretic may slightly increase the effect of these drugs, increase the risk of bleeding blood. The following drugs when taken with Paracetamol may increase the risk of hepatotoxicity: Phenothiazines, anticonvulsants such as Barbiturates, Phenytoin, Carbamazepine or Isoniazid. Alcohol increases the risk of liver toxicity, so do not drink alcohol during treatment with Paracetamol.

Paracetamol repeated use of high doses, or long-term use of the drug or used only once in very high doses can lead to acute toxicity. The most serious toxicity when taking Sacendol is liver necrosis and can even lead to death.
Symptoms of poisoning begin with vomiting, nausea, abdominal pain, cyanosis of the skin, mucous membranes, and nails. In particular, care should be taken when overdosing in children because the symptoms of toxicity will progress faster and more often than in adults.
Neurologically, the symptoms of excitement, delirium will appear first, followed by stupor, hypotension, hypothermia, rapid, shallow breathing, tachycardia, circulatory failure. Symptoms of cardiovascular collapse and shock may occur if very large doses of Paracetamol are absorbed.
After 2-4 days of toxic dose administration, liver damage becomes apparent with elevated plasma bilirubin levels, elevated liver enzymes in the blood, extensive liver damage, coagulation disorders, liver failure, renal failure. multiple organs leading to death. Conversely, if it is possible to recover, liver damage can take weeks or months.
Treatment: Several methods can be used to determine the concentration of Paracetamol in the blood, but treatment cannot be delayed even though early diagnosis of a case of Paracetamol poisoning is very important. Therapeutic therapies include gastric lavage, activated charcoal, saline bleach, and the main antidote, oral or intravenous N-acetylcysteine. The drug should be given immediately if there are symptoms of acute poisoning Paracetamol. In addition, supportive ventilation and circulation therapies are also used to ensure hemodynamics for the patient.
Above is all information about Sacendol drug, patients need to carefully read the instructions for use, strictly follow the indications and doses to achieve effective treatment, avoid the risk of overdose or unwanted effects. of drugs.