News

History of Establishment, Mandates, Organizational structure

The Vinmec Research Institute of Stem Cell and Gene Technology (VRISG), led by Professor Liem Thanh Nguyen, is a non-profit biomedical institute as a branch of Vinmec Healthcare system. VRISG was officially established in October 2016 on the basis of excellent achievements over the development of Vinmec Stem Cell and Gene Technology Center, which was created in March 2014.

ASIA’S SCIENTIFIC TRAILBLAZERS: NGUYEN THANH LIEM

Nguyen Thanh Liem leads the Vinmec Research Institute of Stem Cell and Gene Technology in pioneering stem cell-based therapy for cerebral palsy and autism.

Characteristics of hematopoietic stem cells of umbilical cord blood

Umbilical cord blood is a rich source of hematopoietic stem cells (HSCs) and was collected from the placenta and cord. It is an alternative to bone marrow transplantation. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood. HSCs can be effectively developed into different cell lines with using proper cytokine combination. This process is used in medicine, especially in hematology.

An erk-dependent feedback mechanism prevents hematopoietic stem cell exhaustion

Hematopoietic stem cells (HSCs), which are located in the bone marrow, also circulate in cord and peripheral blood. Despite high availability, HSCs from steady state peripheral blood are little known and not used for research or cell therapy

Gene correction of beta thalassemia mutations via CRISPR/Cas9 technology

The research team is utilizing CRISPR/Cas9 technology to edit mutated genes that cause RETT syndrome and beta thalassemia. RETT syndrome is a syndrome of autism spectrum disorder that is characterized by mutations in the MECP2 gene (Methyl CpG binding protein 2) located on the sex chromosome X.

Letter from the director

Following the motto “Creative and More Creative”, the VRISG focuses all its resources to become the pioneer in Biomedicine and Regenerative Medicine research and application in Vietnam and the region.