1. What medication is Glotizin?
Glotizin 10mg contains the active ingredient Cetirizine hydrochloride 10mg and other excipients. The medication is formulated in the form of film-coated tablets and is used to treat symptoms of allergic conditions such as:
• Seasonal allergic rhinitis or perennial allergic rhinitis;
• Allergic conjunctivitis;
• Chronic urticaria;
• Skin conditions causing itching due to allergies.
2. Instructions for using Glotizin
Glotizin 10mg needs to be used according to the doctor's instructions, or the patient may refer to the dosage references below:
• Children over 6 years old and adults: Take the usual dose - 1 Glotizin 10mg tablet per dose;
• Patients with impaired liver function: No dose adjustment is needed, except in cases of liver failure combined with moderate to severe kidney failure, in which case the dosage should be adjusted.
• Patients with impaired kidney function: The dosage will be adjusted by the doctor based on kidney function response. Specifically:
• Creatinine clearance (Clcr) ≥ 80ml/min: Take 1 tablet once a day;
• Creatinine clearance (Clcr) 50 - 79ml/min: Take the usual dose as in healthy individuals;
• Creatinine clearance (Clcr) 30 - 49ml/min: Take 5mg once a day;
• Creatinine clearance (Clcr) 11 - 49ml/min: Take 5mg once every 2 days;
• End-stage renal failure or on dialysis (< 10ml/min): Not allowed to use.
Usage: Take orally, during or without meal, with an adequate amount of water.
3. Side effects of Glotizin
In some cases, Glotizin 10mg may cause certain adverse effects, such as:
• Common side effects: Mild gastrointestinal disturbances, dizziness, drowsiness, dry mouth, fatigue, nausea.
• Less common side effects: Flushing, increased salivation, loss of appetite or increased appetite, urinary retention.
• Rare side effects: Severe hypotension, anaphylactic shock, hepatitis, cholestasis, glomerulonephritis, hemolytic anemia, thrombocytopenia.
If you experience any of the above side effects, promptly inform your doctor or a qualified pharmacist for timely assistance.
4. Precautions when using Glotizin
Before using Glotizin for treatment, users should pay special attention to the following precautions:
• Do not use the medication for individuals who need to remain highly focused while working, driving, or operating machinery;
• Avoid using Cetirizine in combination with alcohol or other central nervous system depressants, as it may impair alertness;
• The dosage should be reduced in elderly patients;
• Dosage adjustment is required for patients with liver or kidney impairment.
In addition, Glotizin is contraindicated in the following cases:
• Hypersensitivity to any component of the medication or to hydroxyzine;
• Patients with end-stage renal failure;
• The formulation contains lactose, so Glotizin should not be used in patients with glucose-galactose malabsorption, hereditary galactose intolerance, or lactase deficiency;
• This medication should not be used during pregnancy;
• It is not recommended for use in breastfeeding women, as cetirizine is excreted in breast milk.
5. Drug interactions with Glotizin
To avoid unintended interactions, do not use Glotizin in combination with:
• Bronchodilator medication Theophylline 400mg: This medication may reduce the clearance of Cetirizine.
• Alcohol and central nervous system depressants: These can enhance drowsiness, reduce alertness, and pose a danger when performing tasks that require concentration.
Overall, Glotizin has the advantage of quickly alleviating symptoms caused by allergic rhinitis. The medication has a cheap price, comes in tablet form, making it easy to carry and convenient to use. However, despite these advantages, the medication has some limitations such as it should not be used in patients with end-stage renal failure, and in pregnant or breastfeeding women.
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