Klacid 125mg/5ml is a prescription medication with clarithromycin as its active ingredient, formulated as a suspension. This article will provide information about Klacid 125mg/5ml and its uses, dosage as well as instructions for use.
1. What is Klacid 125mg/5ml used for?
The active ingredient, clarithromycin, in Klacid 125mg/5ml is an oral formulation primarily used for children. It is available in a granulated form that can be shaken to mix into a liquid. Clarithromycin is a semisynthetic macrolide antibiotic that is white in color and completely insoluble in water. Klacid 125mg/5ml is packaged in bottles of either 60ml or 30ml.
2. Indications for Klacid 125mg/5ml
Klacid 125mg/5ml is indicated for following cases:
- Upper respiratory tract infections, such as streptococcal pharyngitis.
- Lower respiratory tract infections, such as pneumonia and bronchitis.
- Skin and soft tissue infections, including folliculitis, impetigo, cellulitis, or abscesses.
- Localized or disseminated infections caused by Mycobacterium, including M.intracellulare and M. avium.
- Localized infections caused by M. fortuitum, M. chelonae, or M. kansasii.
3. Contraindications for Klacid 125mg/5ml
Klacid 125mg/5ml is contraindicated in the following cases:
- Hypersensitivity to macrolide antibiotics or any ingredient in Klacid 125mg/5ml.
- Concurrent use with cisapride, astemizole, pimozide, terfenadine, ergotamine, or dihydroergotamine, or HMG-CoA reductase inhibitors.
- History of ventricular arrhythmia or prolonged QT interval on ECG.
- History of severe liver or kidney dysfunction.
4. Dosage and Administration of Klacid 125mg/5ml
Usage: Klacid 125mg/5ml is taken orally. Shake the bottle well before each use. It can be taken with or without food. The treatment duration depends on the condition being treated.
Dosage:
- Children aged 6–12 years: 7.5mg/kg twice daily. For non-mycobacterial infections, the maximum dose is 500mg twice daily. Treatment duration is typically 5–10 days, depending on the severity and pathogen.
- Patients with renal impairment: If creatinine clearance is less than 30ml/min, reduce the dose by half (250mg once daily) or 250mg twice daily for severe infections). Note that duration should not be more than 14 days.
- Treatment for Mycobacterium Infections: For children with localized or disseminated Mycobacterium infections (such as M. intracellulare, M. fortuitum, M. avium, M. chelonae, or M. kansaii), administer 15–30 mg/kg/day, divided into two doses daily.
Note: The dosage of Klacid 125mg/5ml mentioned above is for reference only. The exact dosage depends on the patient's condition and the progression of the illness. To determine the appropriate dosage, patients should consult a doctor or medical professional.
Management in case of missed dose: It should be taken as soon as possible. However, if it is nearly time for the next scheduled dose, skip the missed dose and proceed with the next one. If an overdose of Klacid 125mg/5ml occurs, symptoms such as diarrhea, abdominal pain, and nausea may appear. Patients should discontinue the medication immediately and seek medical attention at the nearest healthcare facility for prompt management.
5. Side Effects of Klacid 125mg/5ml
Potential side effects of Klacid 125mg/5ml include:
- Nausea, vomiting
- Abdominal pain
- Diarrhea
- Mouth inflammation
- Tongue inflammation
- Headache
- Taste disturbances.
- Hives
- Rash
- Anaphylactic reactions.
- Stevens-Johnson syndrome
- Pseudomembranous colitis.
- Liver dysfunction.
Discontinue use of Klacid 125mg/5ml immediately and contact a healthcare provider if any of these symptoms occur.
6. Drug Interactions of Klacid 125mg/5ml
Klacid 125mg/5ml may interact with the following drugs:
- Terfenadine
- Ergot derivatives
- Cisapride
- Pimozide
Therefore, you should inform your doctor about all medications or supplements being taken to avoid interactions.
5. Precautions When Using Klacid 125mg/5ml
- Use with caution in individuals operating vehicles or machinery.
- Monitor closely in patients with severe liver or kidney dysfunction.
- Pregnant or breastfeeding women should consult a doctor before use.
- Do not use it if the medication shows signs of spoilage, discoloration, or is expired.
This article provides complete information about Klacid 125mg/5ml. Patients should carefully read the instructions for use and consult a doctor or pharmacist before taking the medication. It is strictly advised not to self-medicate with Klacid 125mg/5ml at home, as it may lead to undesirable side effects.
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