1. What is Nimegen used for?
The main ingredient of Nimegen, Isotretinoin, is a medication used to treat acne. It is specifically prescribed for severe inflammatory acne that leads to scarring caused by excessive sebum secretion and irritation. Isotretinoin helps reduce secretion and stimulate sebaceous glands, effectively reducing scarring. Nimegen is commonly indicated in the following cases:
- Treatment of severe acne, especially cystic acne, which is resistant or minimally responsive to traditional treatments like topical creams, drying agents or oral/topical antibiotics.
- After a course of treatment, the medication significantly reduces or improves long-term symptoms.
- Due to potential adverse reactions, Isotretinoin should only be used for severe, resistant acne.
- Nimegen is contraindicated in patients with hypersensitivity to any of its components, as well as in pregnant and breastfeeding women. Additionally, patients should not donate blood while using the medication.
2. Dosage and Administration of Nimegen
Nimegen is formulated as soft capsules for oral administration, taken with meals. Patients must not chew the capsules and should avoid consuming alcohol during treatment. Limiting sun exposure is also recommended, as it may reduce the medication's efficacy. The dosage varies depending on the patient and treatment goals:
- Initial dose (first 15-20 weeks): 0.5-1 mg/kg/day, divided into two doses daily. Do not exceed 2 mg/kg/day.
- Typical maintenance dose: 0.1-1 mg/kg/day as directed by a doctor. Discontinue use for at least two months before starting another treatment cycle.
- Dosage for children over 12 years old: Same as adults
- Dosage for patients with severe renal impairment: Start with 10 mg/day, gradually increasing to 1 mg/kg/day depending on treatment response.
3. Side Effects of Nimegen
Some patients using Nimegen may experience the following side effects:
- Dry skin, itching, anaphylaxis, or rashes
- Dry nose, nosebleeds
- Mouth sores, dry mouth
- Eye inflammation
- Joint pain
- Skin infections, increased sun sensitivity
- Hepatitis
Rare side effects: Nausea, vomiting, headache and changes in vision
4. Precautions When Using Nimegen
General precautions for using Nimegen include:
- During Nimegen treatment, patients must use continuous contraception, as the medication can cause birth defects.
- Avoid facial peels and waxing during treatment, as it may increase the risk of hypopigmentation or keloid scarring after treatment.
- Avoid sun exposure while taking Nimegen.
- Perform laboratory tests if Nimegen is used in patients with diabetes, obesity, alcohol addiction, or lipid metabolism disorders.
- Do not use Nimegen with Vitamin A, minocycline, tetracycline, or alcohol.
- Discontinue other topical acne treatments before starting Isotretinoin.
Nimegen is a dermatological medication that contains the active component isotretinoin.It is used to treat severe acne by lowering sebum production and controlling sebaceous gland activity. To ensure effective treatment and avoid unwanted side effects, patients must strictly follow the instructions of their doctors and pharmacists.
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