Uses of Nucoxia 90

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Nucoxia 90mg (box of 100 tablets) is a medication used for pain relief and inflammation reduction in bone and joint conditions. Let's explore in detail the uses and effective ways to take Nucoxia 90 in the following article.  

1. What is Nucoxia 90mg?

Nucoxia 90 belongs to the group of pain relievers, antipyretics, non-steroidal anti-inflammatory drugs (NSAIDs), and medications for treating gout and bone-joint diseases. The main ingredient of the drug is Etoricoxib 90mg, along with other excipients.  

Nucoxia 90 is formulated as film-coated tablets, packaged in 10 blisters x 10 tablets per box, and manufactured by Cadila Healthcare, Ltd - India.  

2. Indications for Using Nucoxia 90  

Nucoxia 90 is prescribed for the following conditions:  

• Acute and chronic treatment of pain, swelling, and inflammation in bones, joints, and muscles.  
• Ankylosing spondylitis.  
• Treatment of acute gouty arthritis (gout).  
• Acute and chronic pain relief.  
• Primary dysmenorrhea (menstrual cramps).  
• Pain management for moderate post-dental surgery pain (short-term use).  
• Respiratory tract infections, ear-nose-throat infections, urinary tract infections, urethritis in men, and infections of the skin and soft tissues.  

3. Dosage and Administration of Nucoxia 90  

Nucoxia 90 is administered orally.  

Recommended dosage:  

• Osteoarthritis (degenerative joint disease): 30mg Etoricoxib per day or a maximum of 60mg per day.  
• Rheumatoid arthritis, ankylosing spondylitis: Maximum dose of 90mg Etoricoxib once daily.  
• Post-dental surgery pain: Maximum of 90mg once daily, not exceeding 3 days of use.  
• Acute gout attacks: A single dose of 120mg per day, with a maximum treatment duration of 8 days.  
• Acute pain and primary dysmenorrhea: Maximum of 120mg per day, used for no more than 8 days.  
• Elderly patients: No dose adjustment required.  
• Liver impairment: Child-Pugh score 5-6: Do not exceed 60mg per day. Child-Pugh score 7-9: Reduce dosage to 60mg every 2 days or 30mg daily.  
• Kidney impairment: No dose adjustment required.  
• Children under 16 years: Not yet studied.  

4. Contraindications for Nucoxia 90  

Nucoxia 90 should not be used in the following cases:  

• Allergy to Etoricoxib or any of the drug's ingredients.  
• History of asthma, aspirin/NSAID-induced allergy, urticaria.  
• Congestive heart failure.  
• Uncontrolled hypertension with persistent blood pressure >140/90 mmHg.  
• History of stroke, ischemic heart disease, peripheral arterial disease.  
• Severe liver disease (Child-Pugh score ≥10 or serum albumin <25g/L).  
• Gastrointestinal bleeding or active peptic ulcer disease.  
• Severe progressive kidney disease.  
• Should not be combined with other NSAIDs.  

5. Side Effects of Nucoxia 90  

During the use of Nucoxia 90, some adverse reactions may occur, including:  

• Reduced platelet count.  
• Hypersensitivity reactions, anaphylaxis, anaphylactic shock.  
• Increased blood potassium levels (hyperkalemia).  
• Anxiety, insomnia, drowsiness, confusion, hallucinations, depression, restlessness.  
• Taste disturbances.  
• Blurred vision.  
• Congestive heart failure, angina, palpitations, tachycardia.  
• Hypertensive crises.  
• Bronchospasm.  
• Peptic ulcer, abdominal pain, oral ulceration, gastrointestinal perforation and bleeding, nausea, diarrhea.  
• Hepatitis, increased liver enzymes (AST/ALT), jaundice.  
• Angioedema, rash, itching, erythema, urticaria.  
• Stevens-Johnson syndrome.  
• Toxic epidermal necrolysis.  

6. Precautions When Using Nucoxia 90  

Nucoxia 90 should be used with caution in the following cases:  

• Patients allergic to NSAIDs, aspirin, or COX-2 inhibitors.  
• Current or history of peptic ulcers, Crohn’s disease, gastrointestinal bleeding.  
• Severe liver disease.  
• Dehydration due to vomiting or prolonged diarrhea.  
• History of heart failure, heart disease, angina, coronary artery bypass surgery, peripheral artery disease, transient ischemic attack, or stroke.  
• History of hypertension, as Nucoxia 90 can increase blood pressure.  
• Patients undergoing infection treatment, as Etoricoxib may mask fever symptoms.  
• Elderly patients.  
• Patients with diabetes, high cholesterol, or smoking history, as these conditions increase cardiovascular risks when using Nucoxia 90.  
• Severe kidney disease.  
• Pregnant or breastfeeding women.  
• Children under 16 years old.  

7. Drug Interactions of Nucoxia 90  

Using Nucoxia 90 together with certain medications may lead to interactions, including:  

• Warfarin (blood thinner/anticoagulant).  
• Rifampicin (antibiotic).  
• Methotrexate (used for rheumatoid arthritis and immune suppression).  
• ACE inhibitors (Enalapril, Ramipril) and angiotensin receptor blockers (Losartan, Valsartan) for hypertension and heart failure.  
• Lithium (used for depression treatment).  
• Diuretics (water pills).  
• Ciclosporin, Tacrolimus (immune system suppressants).  
• Digoxin (for heart failure and arrhythmia).  
• Minoxidil (for hypertension treatment).  
• Salbutamol (for asthma treatment).  
• Oral contraceptives.  
• Alcohol, tobacco, and caffeine, which may increase or reduce drug effectiveness.  
• Uncontrolled hypertension, where Nucoxia 90 should not be used.  

Hope this information helps users gain a better understanding of Nucoxia 90 and how to use it appropriately.

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