Oxynorm 5mg belongs to the group of pain relievers, antipyretics, non-steroidal anti-inflammatory drugs (NSAIDS) used for treating gout and musculoskeletal diseases. The medication is formulated as hard capsules, packaged in boxes of 2 blisters of 14 capsules each. Before using Oxynorm 5mg, patients should consult a pharmacist or specialist doctor. Below is some information to better understand what Oxynorm 5mg is.
1. Uses and indications of Oxynorm 5mg
Oxynorm 5mg contains the main ingredient Oxycodone hydrochloride 5mg equivalent to Oxycodone 4.5mg. The medication is indicated for:
• Alleviating moderate to severe pain in patients suffering from cancer pain or post-surgical pain.
• Alleviating severe pain when a strong opioid is needed.
2. Contraindications of Oxynorm 5mg
Oxynorm 5mg is contraindicated for:
• Individuals allergic to Oxycodone, opioid drugs, or any ingredient in Oxynorm 5mg.
• Individuals with respiratory failure, intestinal obstruction, head injury, acute abdomen syndrome, chronic respiratory obstruction, delayed gastric emptying, chronic bronchial asthma, pulmonary heart disease, moderate to severe liver failure, elevated carbon dioxide in the blood, severe renal failure (CrCl < 10mL/min), or chronic constipation.
• Currently using MAO inhibitors or within 2 weeks after discontinuing MAO inhibitors.
• Pregnant women.
3. Dosage and administration of Oxynorm 5mg
Method of use: Oxynorm 5mg is taken orally. The dosage will be prescribed according to the level of pain and the patient's history regarding pain relief requirements. The interval between doses of Oxynorm 5mg is 4 - 6 hours. Patients need to swallow the entire Oxynorm 5mg capsule. Do not chew, crush, or break as it may increase side effects when used.
Reference dosage:
• For elderly individuals and adults over 18 who seldom use opioid drugs or have severe uncontrolled pain with mild opioids: The starting dose of Oxynorm is 5mg, taken every 4 - 6 hours. Then carefully and frequently adjust the Oxynorm 5mg dose once a day. If needed to achieve the desired pain relief effect, morphine should be taken orally before using Oxynorm 5mg. The daily dose of Oxynorm 5mg is based on the ratio of 10mg of Oxycodone hydrochloride equivalent to 20mg of morphine.
• For adults with mild to moderate renal failure or mild liver failure and rarely use opioid drugs: Careful use of Oxynorm 5mg is required. The starting dose of Oxynorm is 2.5 mg, every 6 hours.
• For patients under 18 years old: The use of Oxynorm 5mg is not recommended in this case.
Note: The above Oxynorm 5mg dosage is for reference only. The specific dosage of Oxynorm 5mg depends on the patient's condition and the progression of the disease. For an appropriate Oxynorm 5mg dosage, patients need to consult a doctor or healthcare professional.
4. Interactions of Oxynorm 5mg
Oxynorm 5mg may cause interaction reactions if used simultaneously with:
• MAO inhibitors;
• Quinidine;
• Cimetidine;
• P450-3A inhibitors such as ketoconazole;
• Erythromycin;
• Sedatives;
• Anesthetics;
• Sleeping pills;
• Antidepressants;
• Phenothiazines;
• Antipsychotics;
• Alcohol;
• Other opioids;
• Muscle relaxants and antihypertensives.
To avoid interactions, before being prescribed Oxynorm 5mg, patients should inform the doctor about all medications currently being used, including dietary supplements. The doctor will base the prescription of Oxynorm 5mg on this information.
5. Side effects of Oxynorm 5mg
Oxynorm 5mg has a high safety profile and rarely causes unwanted side effects. However, using Oxynorm 5mg at high doses or for extended periods may cause unwanted effects such as:
• Loss of appetite;
• Anxiety;
• Confusion;
• Insomnia;
• Tension;
• Cognitive disturbances;
• Abnormal dreams;
• Headaches;
• Dizziness;
• Sedation;
• Drowsiness.
• Bronchospasm;
• Difficulty breathing;
• Reduced cough reflex;
• Constipation;
• Nausea and vomiting;
• Dry mouth;
• Indigestion;
• Abdominal pain;
• Diarrhea;
• Increased sweating;
• Itching and rashes;
• Weakness;
• Chills.
Patients need to stop using Oxynorm 5mg immediately upon noticing any of the above side effects or any other unusual symptoms. They should quickly notify their treating physician or go to the nearest healthcare facility for timely management.
6. Caution when using Oxynorm 5mg
Caution should be exercised when using Oxynorm 5mg in individuals with:
• Opioid dependence;
• Increased intracranial pressure;
• Reduced blood pressure;
• Reduced blood volume;
• Psychotic disorders;
• Biliary tract diseases;
• Pancreatitis;
• Ulcerative colitis;
• Benign prostatic hyperplasia;
• Adrenal cortical insufficiency;
• Acute alcohol dependence;
• Acute alcohol delirium;
• Chronic liver and kidney diseases;
• Severe lung diseases and frailty;
• History of substance or alcohol abuse;
• Old age and frailty;
• Hypothyroidism (reduce dosage);
• Post-abdominal surgery (until intestinal function normalizes).
• Breastfeeding women,
• Intestinal obstruction.
7. Notes when using Oxynorm 5mg
• Do not use Oxynorm 5mg within 6 hours before surgical intervention. If continuing therapy with Oxynorm 5mg, the dosage should be adjusted according to postoperative requirements.
• Patients will be at risk of respiratory failure when using excessive amounts of Oxynorm 5mg.
• There is a potential for psychological drug dependence when using Oxynorm 5mg for an extended period.
• The ingredient Sunset Yellow in Oxynorm 5mg may cause allergic reactions such as asthma (common in patients who are allergic to aspirin).
• Abusing Oxynorm 5mg in oral formulation for injection can lead to serious consequences, including death.
• It is not advisable to drive or operate machinery after using Oxynorm 5mg.
• In case of forgetting a dose of Oxynorm 5mg, it should be taken as soon as possible. However, if it is close to the time for the next dose, the missed dose should be skipped and the new dose should be taken.
• When using an overdose of Oxynorm 5mg, patients need to stop the medication immediately and go to the nearest medical facility for timely treatment.
• Absolutely do not use Oxynorm 5mg if the medication shows signs of discoloration, mold, leakage, or has expired.
The above information is about Oxynorm 5mg. Patients need to carefully read the instructions for use and consult a doctor or pharmacist before use. It is strictly prohibited to self-medicate with Oxynorm 5mg at home as there may be unwanted side effects.
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