This article was written by MD, Specialist level I - Vo Khac Khoi Nguyen - Orthopedic Surgeon, Department of General Surgery, Vinmec Central Park International General Hospital. Patients with diabetes mellitus may experience musculoskeletal disorders, which can cause pain and various functional impairments. Musculoskeletal disorders in diabetic patients negatively affect treatment outcomes and reduce quality of life, due to their impact on the ability to exercise.