Thalassemia is a hereditary hemolytic disorder inherited in an autosomal recessive pattern, passed from parents to children through generations. The primary manifestation of the disease is anemia, which can lead to severe complications and significantly impact the genetic health of a population. Undergoing pre-marital screening tests is essential for accurately detecting Thalassemia genes, determining whether prospective parents are carriers, and assessing the potential risk of Thalassemia in their future children.