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Coxileb 200 is a medicine that helps relieve pain and reduce fever. Coxileb 200 is often used to treat bone and joint diseases, gout, menstrual pain... Using Coxileb 200 exactly as prescribed by your doctor will help you ensure safety for your health and maximize its effectiveness. disease treatment results.
1. What is Coxileb 200?
Coxileb 200 is a medicine that helps relieve pain and reduce fever. Coxileb 200 is often used to treat bone and joint diseases, gout. Coxileb 200 is available in the form of hard capsules. In each hard capsule of Coxileb drug contains the following ingredients:
Celecoxib 200mg; Other excipients: Croscarmellose sodium, spray-dried lactose monohydrate, povidone K30, magnesium stearate, lauryl sulfate.
2. Uses of the drug Coxileb 200
Coxileb 200 is commonly used to treat the following diseases:
Treatment of rheumatoid arthritis in adults, reducing signs and symptoms of chronic arthritis; Relieve acute pain and primary dysmenorrhea, toothache; Treatment of osteoarthritis, supportive to reduce the frequency of colorectal adenoma polyps in patients with familial adenomatous polyposis; In addition, Coxileb 200 is also indicated in some other cases when prescribed by a doctor.
3. Contraindications of the drug Coxileb 200
Coxileb 200 should not be used in the following cases:
Patients with a history of allergy or hypersensitivity to any of the ingredients in Coxileb 200; Pregnant women in the last 3 months of pregnancy and breastfeeding; Patients with a history of allergies such as rhinitis, urticaria, angioedema to Aspirin, non-steroidal anti-inflammatory drugs, antibiotics Sulfonamides; Patients with severe renal impairment with creatinine clearance less than 30ml/min; Patients with moderate to severe heart failure, liver failure; Have inflammatory bowel diseases such as crohn, ulcerative colitis.
4. Dosage and how to use coxileb 200
Used to treat chronic osteoarthritis in adults: The dose of Coxileb 200mg/time x 1-2 times/day; Used to treat rheumatoid arthritis in adults: Coxileb dose 200mg/time x 2 times/day; For the management of acute pain and dysmenorrhea: 400 mg starting dose. Additional dose of 200mg of Coxileb drug if necessary on the first day, the interval between the first dose and the additional dose must be at least 4 hours, the following days take a dose of Coxileb 200mg/time x 1-2 times/day; Used for adjuvant treatment to reduce the frequency of colorectal adenoma polyps in patients with familial adenomatous polyposis: 400mg/time x 2 times/day. Note: The dose of Coxileb 200 should be reduced by half in patients with moderate hepatic impairment.
The drug Coxileb 200 is prepared in the form of hard capsules, for oral use. Coxileb 200 can be taken on an empty stomach or on an empty stomach.
5. Side effects of the drug Coxileb 200
Coxileb 200 may cause unwanted effects including:
Itching, urticaria, subcutaneous rash, exfoliative dermatitis; Headache, dizziness, nervousness, dizziness, tinnitus; Abdominal pain, nausea, vomiting, constipation, diarrhea, gastrointestinal bleeding; Bronchitis, cough, rhinitis, sinusitis, upper gastrointestinal tract infection; Arthralgia, back pain, muscle pain, risk of venous thrombosis.
6. Be careful when taking medicine
Coxileb 200 should be used with caution in the following cases:
Patients with a history of cerebrovascular disease; Ischemic heart disease; Patients with risk factors for cardiovascular disease; Peripheral artery disease; Patients with a history of gastrointestinal bleeding, asthma or allergic diseases; Patients with a history of impaired liver and kidney function, hypertension; Coxileb 200 should be used with caution in patients with dehydration, and rehydration is recommended prior to administration.
7. Drug interactions
Coxileb 200 may interact with the following drugs, including:
When used with fluconazole, it increases the plasma concentration of Celecoxib; Concomitant administration of Coxileb 200 with drugs that inhibit or induce the CYP2C9 enzyme or drugs that are metabolised by this enzyme may alter the plasma concentration of Celecoxib; When co-administered with Lithium, Methotrexate and Cardiac Glycosides, Coxileb 200 increases plasma concentrations of these drugs; When used with antihypertensive drugs such as Angiotensin-converting enzyme inhibitors, beta-blockers, diuretics, Coxileb 200 will reduce the antihypertensive effect. Increased risk of gastrointestinal bleeding when Coxileb 200 is co-administered with corticosteroids, anticoagulants, non-steroidal anti-inflammatory drugs or alcohol.
8. Preservation of Coxileb 200
Store Coxileb 200 at room temperature, in a cool, dry place, away from light and reach of children.
The article has provided information on what Coxileb 200 is, dosage and precautions for use. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
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