Uses of Lamotor

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Lamotor is often prescribed by doctors to treat epilepsy, partial spasms,... The following article will provide readers with the necessary information to know how to use the drug effectively. and safe for health.

1. What are the effects of Lamotor?

Lamotor is a drug that contains the main ingredient Lamotrigine. This active substance is effective in the treatment of generalized, partial seizures, typical compulsive disorders. The mechanism of action of the drug is to enhance the activity of GABA receptors, chemical mediators of central neurotransmitters, and increase the sensitivity of the sodium ion channel system.

2. Indications and contraindications


2.1. Indications With the above effect, Lamotor drug is usually indicated for use in the following cases:
Used to replace enzyme-inducing antiepileptic drugs. Used for the control of seizures, partial tonic-clonic seizures in adults. Treatment of generalized epileptic seizures, epileptic seizures with or without tonic-clonic seizures. 2.2. Contraindications Patients should not use Lamotor for the following cases:
People who are sensitive or have a history of hypersensitivity to any of the ingredients in Lamotor. Use Lamotor with caution in patients with severe renal and hepatic impairment.

3. Dosage and usage


3.1. Dosage Lamotor's dosage is divided according to the user's age, disease condition as well as tolerability of the drug for each case. Basically, you can refer to the following treatment regimen:
Children from 2 to 12 years old combined with antiepileptic drugs: In the first 2 weeks of using a dose of 0.15 mg/kg/day, it is possible Drink 1 to 2 times. In the 3rd and 4th weeks, the dose should be 0.3 mg/kg/day, which can be divided into 1-2 doses. Then use the drug with a maintenance dose of 1 to 5 mg/kg/day, which can be divided into 1-2 doses, ensuring maximum dose of 200mg per day. Children aged 2 - 12 years old combined with antiepileptic drugs: In the first 2 weeks, use the drug at a dose of 0.6 mg/kg/day, divided into 1-2 doses. The next 2 weeks, you switch to using a dose of 1-2 mg/kg/day which can be divided into 2 oral doses. Then use the maintenance dose at 5-15 mg/kg/day in 2 divided doses. As recommended, patients take a maximum dose of 400 mg / day depending on the drug condition. Patients > 12 years of age combined with antiepileptic drugs: During the first 2 weeks, use a dose of 25mg/day. When moving to the next 2 weeks, you use a dose of 25mg / day. Then use Lamotor with a maintenance dose of 100-400 mg/day that can be divided into 1-2 times to drink. Patients > 12 years of age in combination with enzyme-inducing antiepileptic drugs: During the first 2 weeks of dosing. 50mg per day. When moving to the next 2 weeks, you use a dose of 100mg per day divided into 2 doses, noon and night. Then use Lamotor with a maintenance dose of 300 - 500mg per day. 3.2 How to take Lamotor medicine Patients should pay attention to take the medicine at the same time of day to avoid forgetting the dose. If you miss a dose of Lamotor you can take a supplement, if it is close to the next dose, you should skip it. In the event of an overdose of Lamotor, the patient should immediately go to the nearest medical facility for timely treatment, to avoid serious consequences, especially life-threatening.

4. Side effects


When taking Lamotor medicine to treat the disease, patients may experience some unwanted effects:
Central nervous system disorders leading to fatigue, headache, dizziness. Gastrointestinal disorders cause nausea, abdominal pain, ... However, these side effects often appear only transient. In case the patient experiences symptoms of rash, hives on the skin, it is necessary to immediately notify the treating doctor and stop the drug to avoid unwanted cases.

5. Drug interactions


Use of Lamotor with Valproat may decrease the metabolism of Lamotor and increase the elimination time. Use with antiepileptic drugs such as Phenytoin, Carbamazepine, Primidone, phenobarbital increases the risk of Lamotor metabolism in the liver. When taking Carbamazepine with Lamotor, patients often feel dizzy, double vision, nausea.... Used with Lamotrigine to increase the concentration of Topiramate in the drug.

6. Note when using Lamotor


Do not use stimulants during drug use to avoid interactions and health effects. When not needed, absolutely do not stop the drug suddenly, but reduce the dose gradually, usually 2 weeks. Use caution when using Lamotor for people who often drive and operate mechanical vehicles. Pregnant women can use the drug at the lowest dose prescribed by a medical professional. For women who are breastfeeding, the active ingredient in Lamotor can be excreted in breast milk, so caution should be exercised when using the drug for this group of subjects. Above is the basic information about Lamotor medicine that you can refer to. To use the drug safely, contact a specialist, a medical professional, absolutely do not self-medicate at home.

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