Uses of Newcilotal

Newcilotal belongs to the group of pain relievers for moderate to severe pain. The main ingredients in the drug are Tramadol and Acetaminophen. To ensure effective use, patients need to strictly follow the instructions of the doctor, professional pharmacist.

What is Newcilotal? Newcilotal is a non-steroidal anti-inflammatory drug that belongs to the group of analgesics, antipyretics and anti-inflammatory drugs. The drug is used in the treatment of Gout and other bone-related diseases. The drug is manufactured at Nexpharm Korea Co., Ltd.
The drug is prepared in the form of tablets and packed in boxes, each box of 10 blisters x 10 tablets. The drug has the main ingredients Tramadol HCl 37.5mg and Acetaminophen 325mg. In addition, there are other active ingredients and excipients sufficient.

Newcilotal is indicated for the treatment of moderate to severe pain. Tramadol ingredient has the effect of helping to relieve central pain, relieve eye pain, irritation, and redness after cataract surgery. Accordingly, Newcilotal is indicated in the following cases:
People suffering from colds, flu, tears, fever, pain due to injuries, accidents Overwork, headaches, osteoarthritis pain

Newcilotal is contraindicated in the following cases:
Women who are breastfeeding should not use it, because the safety of the drug to the baby has not been clearly studied. Patients with a history of sensitivity to active ingredients Tramadol, Paracetamol. In case of acute poisoning due to alcohol, pain relievers, sleeping pills, narcotics, ...

4.1. How to use You need to carefully read the instructions for use of the drug, do not arbitrarily use the drug in other ways not stated in the instruction sheet for using Newcilotal Tablet.
Newcilotal Tablet is in the form of tablets that should be used orally. The process of using the drug should be approved by a qualified treating doctor 4.2. Dosage Adults and children over 12 years old: maximum use from 1-2 tablets in 4-6 hours. Do not use more than 8 tablets/day. When taking the drug is not affected by food. Children < 12 years old: There are no accurate studies on safety and effectiveness in this age group. Elderly (over 65 years): There were no differences in the safety or pharmacokinetics of Newcilotal.

5.1. Overdose During drug use, if an overdose is suspected or there are symptoms of overdose or symptoms of tramadol, paracetamol poisoning, the patient may experience the following side effects:
Respiratory depression Coma Convulsions Cardiac arrest and death Hepatotoxicity Gastrointestinal irritation Anorexia Nausea, Vomiting Irritability Pale Sweating. The above symptoms may appear 48-72 hours after taking the drug.
Treatment of overdose is as follows:
Dialysis only removes about 7% of the drug taken within 4 hours of dialysis. Therefore, first of all, ventilation must be ensured along with other treatments to reduce drug absorption. Use mechanical emesis or ipecac syrup if the patient is critically ill. Drink 1g/kg of activated charcoal after cleaning the stomach. Before performing gastric lavage, an endotracheal tube should be placed. Plasma concentrations of paracetamol should be determined and treated with acetylcysteine. If it is difficult to determine the estimated amount of paracetamol taken in excess of 7.5 -10g for adults and adults, 150 mg/kg for children, N-acetylcysteine ​​should be taken first and applied other remedial measures. In case of overdose, requiring emergency hospitalization, relatives need to bring the prescription that the victim has taken, and at the same time inform the doctor about the height and weight of the victim. 5.2. What should I do if I miss a dose? If you miss a dose while using Newcilotal, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

6.1. Note During the use of Newcilotal drug to treat the disease. You need to carefully note the following:
Drugs with a risk of convulsions when tramadol is used concurrently with SSRIs, TCAs, Opioids, MAOIs, tranquilizers, drugs that lower the seizure threshold. Use with caution in patients with epilepsy, history or risk of seizures. The drug has a potential to cause respiratory depression in patients diagnosed with possible respiratory failure. Using high doses of tramadol with local anesthetics, anesthetics, sleeping pills, sedatives, alcohol. Use with caution in patients with increased intracranial pressure or head trauma. Patients with opiate addiction, chronic alcoholism, because of the risk of hepatotoxicity. There may be an increased risk of convulsions when Naloxone is used in the treatment of Tramadol overdose in patients with severe hepatic impairment. Using the drug during pregnancy can cause adverse effects such as miscarriage, birth defects. .. Therefore, the drug should not be used by pregnant women, except in cases where it is imperative to consult a doctor. During lactation, the drug can pass through breast milk, so its use should be limited.

Usually the side effects when using Newcilotal drugs occur on the central nervous system and digestive system as follows:
Nausea, dizziness, dizziness Body weakness, fatigue Headache, shivering Abdominal pain Diarrhea Constipation Skin itching, skin rash and increased sweating Syncope, chills, chest pain Hypertension Low blood pressure Loss of balance Muscle pain Weight loss Anemia Arrhythmia, palpitations, rapid pulse Black stools Unusual vision The above are not all side effects of Newcilotal Tablet. If you have any other side effects not listed above or in the leaflet, please consult your doctor or pharmacist.

When used at the same time, two or more drugs are often prone to drug interactions leading to antagonism or synergism.
8.1. Interactions with other drugs Concomitant use of drugs with MAO inhibitors, serotonin reuptake may increase the risk of side effects, seizures, serotonin syndrome. The analgesic effect of tramadol in the drug may be reduced in patients taking carbamazepine. Taking quinidine along with medications can increase tramadol levels. Concomitant use with CYP2D6 inhibitors such as fluoxetine, paroxetine and amitriptyline may limit the metabolism of tramadol. Concomitant use with cimetidine has not been studied. Co-administration of Newcilotal with cimetidine did not alter the clinical pharmacokinetics of tramadol. 8.2. Interaction of Newcilotal with food and drink There will be drug interactions when used with foods such as alcohol, beer, tobacco, stimulants, etc. From there, affecting and causing symptoms resistant or synergistic with drugs. Patients should read the leaflet carefully before using Newcilotal or consult a doctor or pharmacist when using it with food, alcohol and tobacco. Newcilotal belongs to the group of pain relievers for moderate to severe pain. The main ingredients in the drug are Tramadol and Acetaminophen. To ensure effective use, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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