In which case is bone scintigraphy in the area of ​​less enhancement seen?

Question
Hello doctor,
Could you please tell me in which case the bone scans are less enhanced? Thank you doctor.
Anonymous customer
Answer
Answered by Master, Doctor Nguyen Viet Thu - Department of Diagnostic Imaging and Nuclear Medicine, Vinmec Times City International General Hospital.
Hello,
With the question “In which case is bone scan of the less enhanced area seen? ", the doctor would like to answer as follows:
Bone scintigraphy is a technique using the SPECT/CT machine system to help diagnose a number of bone diseases. Your doctor may order a bone scan if you have bone pain that has not been diagnosed, or if you have a bone infection or bone injury that cannot be clearly identified on an X-ray. .
Bone scintigraphy is also a very important means of detecting whether cancer has spread (metastasized) into the skeletal system, for example in breast cancer, prostate cancer, lung cancer, etc. ..
Your question above will be understood as the area with less concentration of radioactivity (drug) inside the bone (or less distribution of radiopharmaceutical inside the bone), when the radiopharmaceutical is put into the body will be recorded by imaging devices such as (SPECT, SPECT/CT) from outside the body.
Thus, the area with a lot of radioactive activity is a damaged area like primary bone cancer; metastatic cancer to the bone; some benign bone lesions such as fibrous dysplasia; fracture; some metabolic bone diseases such as osteomalacia, hyperparathyroidism; osteoarthritis diseases; avascular necrosis,...
The area of ​​concentration of radioactivity in bone according to physiological characteristics and in general, radioactivity decreases with age.
Few areas, very little concentration of radioactivity such as osteoporosis, soft tissue.
Areas where radioactivity is not concentrated such as bone defects, some bone cystic lesions,...
If you still have questions about bone scans in areas with less enhancement, you can go to a hospital belonging to Medical System Vinmec for further inspection and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!