Possible interactions with vitamin D

Vitamin D is essential for the regulation of the minerals calcium and phosphorus found in the body. It also plays an important role in building structure and making bones strong. However, there are some interactions that can occur when you take vitamin D.

Vitamin D is needed to build and maintain strong bones because calcium is a major component of bones and can only be obtained when your body absorbs enough vitamin D. Your body makes vitamin D when direct sunlight converts a chemical in the skin to the form of calciferol (vitamin D2).
Vitamin D is not found in many foods but you can get it from fortified milk, fortified cereals and fatty fish like salmon, mackerel and sardines.
The amount of vitamin D your skin makes depends on many factors; including time of day, season, latitude and your skin pigmentation. Depending on where you live and your lifestyle, vitamin D "production" may be reduced or completely absent during the winter months. Sunscreen, which is important for the skin, can also reduce vitamin D production.
Many older people are not regularly exposed to sunlight and have difficulty absorbing vitamin D, so take a multivitamin A combination of vitamin D will help improve bone health. The recommended daily intake of vitamin D is 400 international units (IU) for children under 12 months of age, 600 IU for ages 1 to 70 years, and 800 IU for people over 70 years of age.

Aluminum: Long-term use of vitamin D and aluminum-containing phosphate binders can cause harmful aluminum levels in people with kidney failure.
Anticonvulsants: The anticonvulsants phenobarbital and phenytoin (Dilantin, Phenytek) increase the breakdown of vitamin D and decrease calcium absorption.
Atorvastatin (Lipitor): Taking vitamin D can affect how your body processes this cholesterol drug.
Calcipotriene (Daivonex): Do not take vitamin D with this psoriasis medication. The combination of these two medicines can increase your risk of getting your blood calcium levels too high (hypercalcemia).
Cholestyramine (Prevalite): Taking this weight loss drug may reduce the absorption of vitamin D.
Cytochrome P450 3A4 (CYP3A4) substrate: This is a system of 50 monooxygenase enzymes found in most foods. living body. This powerful enzyme system plays an important role in human physiology. Use vitamin D with caution if you are taking medications that are metabolized by these enzymes.
Digoxin (Lanoxin): Avoid taking high doses of vitamin D with this cardiovascular drug. That can cause hypercalcemia, which increases the risk of fatal heart problems from digoxin.
Diltiazem (Cardizem, Tiazac): Avoid taking high doses of vitamin D with this blood pressure medication. High doses of vitamin D can cause hypercalcemia, reducing the effectiveness of the drug.
Orlistat (Xenical, Alli): Taking this weight loss drug may decrease the absorption of vitamin D.
Thiazide diuretics: These blood pressure medications may decrease urinary excretion of calcium. This can lead to hypercalcemia if you are taking vitamin D.
Steroids: Taking steroid intermediates such as prednisone can decrease calcium absorption and reduce your body's processing of vitamin D. Stimulant laxatives: Long-term use of high doses of stimulant laxatives can decrease absorption of vitamin D and calcium.
Verapamil (Verelan, Calan): Avoid taking high doses of vitamin D with this blood pressure medication. High doses of vitamin D can cause hypercalcemia, reducing the effectiveness of the drug.

Your body must have vitamin D to absorb calcium and promote bone growth. Too little vitamin D leads to soft bones in children (rickets) and fragile, deformed bones in adults (osteomalacia).
Vitamin D deficiency is now linked to breast cancer, colon cancer, prostate cancer, heart disease, depression, weight gain and other diseases. These studies suggest that people with higher levels of vitamin D have a lower risk of the disease, although they do not definitively prove that vitamin D deficiency causes disease or that taking vitamin D supplements reduces the risk. sick.
Use of vitamin D may be helpful in treating or preventing autism, autoimmune disease, cancer, chronic pain, depression, diabetes, heart disease, high blood pressure, flu, neurological disease muscle and osteoporosis. Vitamin D plays a very important role in each person's body. Therefore, you should supplement this vitamin fully and properly to avoid diseases caused by excess or deficiency of vitamin D.
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