Uses of Roxithromycin 150mg

What is Roxithromycin 150mg? The drug has the main ingredient Roxithromycin 150mg and excipients (Lactose, Sodium starch glycolate, Povidone, corn starch, Magnesium stearate, Colloidal silicon dioxide).
Roxithromycin is a semi-synthetic antibiotic belonging to the Macrolide group, with a broad spectrum of activity against gram-positive and some gram-negative bacteria. Regarding the mechanism of action, Roxithromycin reversibly binds to the 50S subunit of susceptible bacterial ribosomes, inhibiting bacterial protein synthesis, thereby giving the ability to kill bacteria effectively.
Indications for the use of Roxithromycin: Treatment of infections caused by susceptible bacteria:
Infections of the lower respiratory tract and ear - nose - throat such as: bronchitis, pharyngitis, pneumonia, sinusitis, inflammation middle ear , esophagitis , tonsillitis ; Skin and soft tissue infections: Boils, toxic boils, cystitis, pyoderma, impetigo, infectious dermatitis, infectious ulcers, erysipelas; Oral infections; Non-gonococcal urogenital tract infections: Cervicitis - vaginitis, prostatitis, vaginitis, salpingitis, especially caused by Chlamydia infection, urethritis. Contraindications to the use of Roxithromycin:
People with hypersensitivity to the ingredients and excipients of the drug; Co-administration of Roxithromycin with ergotamine-type vasoconstrictor compounds; Patients taking Terfenadine or Astemizole (due to the risk of severe arrhythmias); Children under 6 months old.

Usage: Orally. Roxithromycin 150mg tablet form is suitable for adults and children from 4 years of age and older. It should be taken before meals and should not be used for more than 10 days (unless directed by your doctor).
Dosage:
Adults: Take 1 tablet/time x 2 times/day; Children: Use dose 5-8mg/kg/day, divided into 2 times; Patients with severe hepatic impairment: The dose should be reduced by 1⁄2 the usual dose; Patients with severe renal impairment: No change in the usual dose is required. Overdose: If an overdose occurs when using Roxithromycin 150mg, the patient should go to the nearest hospital for an appropriate treatment plan such as gastric lavage, supportive treatment and symptomatic treatment.
Missed dose: If you forget to take a dose of Roxithromycin 150mg, the patient should take it as soon as possible. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Patients should not take twice the prescribed dose to make up for the missed dose.

Some side effects patients may encounter when using Roxithromycin 150mg include:
Common: Nausea, vomiting, epigastric pain, diarrhea; Uncommon: Rash, urticaria, angioedema, bronchospasm, purpura, anaphylaxis, dizziness, dizziness, headache, decreased taste, decreased sense of smell, paresthesia, increased micro-organisms drug-resistant bacteria, superinfection; Rare: Cholestatic hepatitis, elevated serum liver enzymes, symptoms of pancreatitis (very rare). Patients should inform their doctor about the side effects when using Roxithromycin 150mg to receive appropriate advice and intervention.

Some notes patients need to remember before and while using Roxithromycin:
Be careful when using Roxithromycin 150mg if the patient has severe liver failure because the drug may cause some side effects in the liver; Roxithromycin can cause dizziness, lightheadedness, headache, so caution should be exercised when driving a vehicle or operating machinery; Use caution when using Roxithromycin for pregnant and lactating women because there are currently no studies on the use of the drug in this group of subjects.

Drug interactions can change the ability of the medicine you are taking or increase side effects. Some drug interactions Roxithromycin 150mg include:
Roxithromycin should not be combined with Astemizole, Cisapride, Terfenadine, Pimozide because it may increase the risk of causing severe arrhythmia; Caution should be exercised when Roxithromycin is combined with vitamin K antagonists because it may prolong prothrombin time; Caution should be exercised when Roxithromycin is combined with Disopyramide because it will increase the concentration of unbound Disopyramide in the serum; Caution should be exercised when Roxithromycin is co-administered with Digoxin and other Glycosides as it increases the absorption of Digoxin and Glycosides Roxithromycin may slightly increase plasma concentrations of Theophylline or Cyclosporin A (but no change in the usual dose is required). ); Roxithromycin should not be combined with Bromocriptin because Roxithromycin increases the plasma concentration of Bromocriptin. To avoid the risk of drug interactions, the patient should inform the doctor about the drugs they are taking (including drugs, supplements, herbs,...). To ensure safety, patients are also not allowed to self-medicate, stop taking or change the dose without the consent of the doctor.
Patients should strictly follow the doctor's instructions when using Roxithromycin 150mg. This ensures the drug is most effective at treating infections, while reducing the risk of dangerous side effects or incidents.