1. What are the uses of Brieka 75?
Brieka contains the active ingredient pregabalin. Pregabalin is a 3-isobutyl derivative of gamma-aminobutyric acid (GABA) known for its anticonvulsant, antiepileptic, anxiolytic, and analgesic properties. The mechanism of action of pregabalin is to bind to the alpha-2-delta (A2D) subunits of calcium channels, helping regulate calcium flow at nerve endings. This results in the inhibition of the release of neurotransmitters like glutamate, noradrenaline, serotonin, and dopamine.
Additionally, Pregabalin also effectively reduces the transmission of pain signals by noradrenergic and serotonergic pathways from the brain to the spinal cord, thus helping alleviate fibromyalgia and neuropathic pain.
2. Indications and contraindications of brieka 75
2.1. Indications
With these effects, Brieka 75 is indicated for use in the following cases:
- Patients with central and peripheral neuropathic pain and generalized anxiety disorder.
- Adjunctive treatment for partial-onset seizures with or without secondary generalization.
2.2. Contraindications
Brieka should not be used by individuals who are allergic or hypersensitive to its ingredients or who have the following conditions:
- Heart problems, including congestive heart failure
- Mood disorders, depression, or a history of suicidal thoughts
- Bleeding disorders or a history of angioedema
- Low platelet count, kidney disease, diabetes, alcohol, drug, or substance abuse
To use Brieka correctly and safely, patients should consult their doctor before starting the medication.
3. Dosage and usage of Brieka 75
3.1. Dosage
For patients with neuropathic pain: Start with a dose of 150 mg/day, divided into 2 or 3 doses. After 3-7 days, the dose can be increased to 300 mg/day based on tolerance and response. If necessary, the dose can be further increased to a maximum of 600 mg after 7 days.
For epilepsy patients: Start with a dose of 150 mg/day, divided into 2 or 3 doses. After 1 week, the dose can be increased to 300 mg/day based on tolerance and response. After another week, the dose can be increased to a maximum of 600 mg/day.
For patients with generalized anxiety disorder: Start with a dose of 150 mg/day. After 1 week, the dose can be increased to 300 mg/day based on tolerance and response. After another week, the dose can be increased to 450 mg and a maximum of 600 mg/day.
3.2. Usage
Patients should take Brieka orally, either before or after meals, with plenty of water. It is important not to take the medication with milk or fruit juices. Additionally, the medication should be swallowed whole and not crushed, chewed, or broken, as this can affect its effectiveness.
4. Side effects when using Brieka
Brieka may cause several side effects, including:
- Dizziness, drowsiness, blurred vision, double vision, and vestibular disorders.
- Feelings of euphoria and increased excitability.
- In some cases, reduced libido, erectile dysfunction, disorientation, and insomnia.
- Memory impairment, concentration disorders, paresthesia, sedation, balance disorders, and headaches.
- Dry mouth, constipation, and bloating.
- Increased appetite and weight gain.
- Rare cases of leukopenia, urinary retention, rhabdomyolysis, jaundice, and vision loss.
If you experience any unusual symptoms suspected to be caused by the medication while using Brieka, you should immediately inform your doctor to receive timely medical intervention.
5. Drug interactions
Brieka can interact with several types of medications, including:
- Diabetes medications: such as Pioglitazone and Rosiglitazone
- ACE inhibitors: including Benazepril, Enalapril, Captopril, Lisinopril, Fosinopril, Moexipril, Perindopril, Quinapril, Ramipril, and Trandolapril
- Medications causing drowsiness: like Codeine and Hydrocodone
- Anxiety and insomnia medications: including Alprazolam, Lorazepam, Zolpidem, Carisoprodol, and Cyclobenzaprine
- Antihistamines: such as Cetirizine and Diphenhydramine
You should inform your doctor about all the medications you are currently taking to get advice and avoid potential drug interactions.
6. Precautions when using Brieka
- Patients with renal impairment, diabetes, cardiovascular diseases, and the elderly should use Brieka with caution.
- Children under 12 years, adolescents (12-17 years), pregnant, and breastfeeding women should only use the medication when prescribed by a doctor.
- Discontinue Brieka immediately if symptoms of angioedema appear.
- Monitor for signs of suicidal thoughts and behavior, and do not abuse the medication.
The provided information offers necessary details about Brieka. However, it is for reference purposes only and does not replace a doctor's prescription. Therefore, patients should only use the medication when prescribed to ensure absolute safety.
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