Medikinet MR is a psychotropic medication indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents, as well as adults diagnosed with ADHD according to DSM-IV criteria. To achieve the best therapeutic effect, patients need to follow the medication instructions carefully.
1. What is the effect of Medikinet MR 10mg?
Medikinet MR 10mg is a psychotropic drug containing the active ingredient methylphenidate hydrochloride at a dosage of 10mg. Medikinet MR is used to reduce excessive hyperactive behaviors and improve attention skills in children with ADHD. According to scientists, Medikinet MR has the ability to regulate the levels of neurotransmitters involved in behavior control, particularly increasing the levels of dopamine and norepinephrine in the brain.
Methylphenidate has a short duration of action, typically taking about 30 minutes to 1 hour after ingestion to take effect. The chewable form of the medication has an almost immediate effect. The effects of Medikinet MR can last between 4 to 10 hours, depending on the formulation. After this period, the medication’s effectiveness diminishes, which is why methylphenidate is often taken in the morning on school days.
2. Indications and Contraindications for Medikinet MR
2.1. Indications for using Medikinet MR
Medikinet MR is indicated for use in the following cases:
- Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents aged 6-17 years.
- Adults aged 18-65 years diagnosed with ADHD according to DSM-IV criteria, except for patients with secondary symptoms due to environmental factors or primary psychiatric disorders such as psychosis.
In addition to the above uses, Medikinet MR may be used to treat other conditions not listed here. Therefore, before using this medication, it is important to consult with a doctor for advice and to ensure proper and effective use.
2.2. Contraindications
Medikinet MR should not be used in the following cases:
- Patients with anxiety, noticeable tension, or confusion
- Hypersensitivity to any component of Medikinet MR
- Increased intraocular pressure (glaucoma)
- A family history or diagnosis of Tourette syndrome
- Patients currently undergoing treatment with an MAOI (monoamine oxidase inhibitor), with a discontinuation period of at least 14 days after stopping the MAOI
3. How to use and dosage of Medikinet MR 10mg
Medikinet MR is available in the form of hard capsules, and should be taken orally. The timing of the medication can be before or after meals. The dosage will depend on the patient's condition and age, as follows:
- Children aged 6-12 years: Starting dose is 18 mg/day, with a range of 18-54 mg/day.
- Adolescents aged 13-17 years: Starting dose is 18 mg/day, with a range of 18-72 mg/day (not exceeding 2 mg/kg/day).
- Adults aged 18-65 years: Starting dose is 18 mg or 36 mg/day, with a range of 18-72 mg/day. For those transitioning from another methylphenidate product (10-60 mg/day, divided into 2-3 doses), the initial dose of Concerta is 18 mg/day (if using 5mg methylphenidate, 2 or 3 times a day), or 36 mg/day (if using 10mg methylphenidate, 2 or 3 times a day), or 54 mg/day (if using 15mg methylphenidate, 2 or 3 times a day), or 72 mg/day (if using 20mg methylphenidate, 2 or 3 times a day).
- The dosage should not exceed 72 mg/day.
Patients should use Medikinet MR regularly to achieve the maximum benefit. For safe use, follow the doctor's instructions precisely, do not take more or less than prescribed, and do not extend the duration of treatment on your own. Do not increase the dosage without medical advice, as this may worsen the condition and increase the risk of side effects.
4. Side effects when using Medikinet MR 10mg
Some potential side effects may occur when using Medikinet MR, including:
- Nasopharyngitis
- Cough
- Mouth and throat pain
- Dizziness
- Upper abdominal pain
- Respiratory infection
- Sinusitis
- Loss of appetite, decreased appetite
- Restlessness
- Agitation
- Anxiety
- Teeth grinding during sleep
- Depression
- Mood swings
- Reduced sexual desire
- Panic attacks
- Aggression
- Confusion
- Tremors
- Paresthesia
- Accommodation disorders
- Blurred vision
- Tachycardia (rapid heart rate)
- Palpitations
- Hypertension
- Hot flashes
- Increased sweating
- Muscle tension
- Erectile dysfunction
- Decreased white blood cells, platelets, thrombocytopenic purpura
- Elevated bilirubin levels
- Increased liver enzymes
- Abnormal white blood cell count
- Joint pain, muscle pain, muscle spasms
- Seizures, epilepsy
- Movement disorders
- Disorientation
- Hallucinations (auditory, visual)
Before prescribing the medication, doctors always weigh the benefits and effectiveness of Medikinet MR against the potential risks of side effects. However, in some cases, adverse reactions may still occur when using Medikinet MR. Therefore, if any unusual symptoms appear after taking the medication, especially if a serious allergic reaction occurs with accompanying symptoms such as difficulty breathing, increased dizziness, swelling, rash, or itching in the face, tongue, or throat, the patient or family member should immediately inform healthcare personnel to ensure timely intervention.
5. Some precautions when using Medikinet MR 10mg
Some important precautions when using Medikinet MR include:
- Inform your doctor if you have a history of allergies to Medikinet MR or any other allergies. Medikinet MR may contain inactive ingredients that can cause allergic reactions or other serious issues.
- Inform your doctor about any other medications you are taking, including prescribed medicines, over-the-counter drugs, herbal supplements, and any foods or preservatives.
- Exercise caution when using Medikinet MR in patients with abnormal heart structure, cardiomyopathy, coronary artery disease, arrhythmias, pre-existing mental disorders, bipolar disorder, psychiatric symptoms, mania, a history of seizures, history of drug dependency, alcohol addiction, gastrointestinal narrowing, pregnant or breastfeeding women, etc.
- During treatment with Medikinet MR, monitor for any occurrence or worsening of aggressive or oppositional behaviors, evaluate the cardiovascular condition, monitor erectile dysfunction, monitor growth in children, and monitor for any visual disorders.
- Perform periodic blood tests if undergoing long-term treatment.
- Do not use this medication to treat severe depression or to prevent or treat normal fatigue.
- For pregnant and breastfeeding women, safety data is insufficient, so Medikinet MR should only be used when the benefits outweigh the potential risks.
- If you forget a dose, take it as soon as possible. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not double the dose to make up for a missed one. Taking an overdose of Medikinet MR can cause serious symptoms such as nausea, vomiting, abdominal pain, and weakness.
6. Drug interactions
Drug interactions may reduce the effectiveness of Medikinet MR or increase the risk of unwanted side effects. Be sure to inform your doctor about all the medications you are currently using, including vitamins, prescription drugs, over-the-counter medications, and herbal products. Do not stop, start, or change the dose of any medication without your doctor's approval.
Some drugs that may interact with Medikinet MR include:
- MAOIs (Monoamine oxidase inhibitors)
- Coumarin
- Anticonvulsants
- Antidepressants
7. How to store Medikinet MR 10mg
Store Medikinet MR at room temperature, away from light and moisture. Do not store it in damp places or in the freezer. Each medication may have different storage requirements, so be sure to read the storage instructions on the packaging or ask your pharmacist. Keep Medikinet MR out of the reach of children and pets. When the medication has expired or is no longer needed, dispose of it according to the correct procedure. Do not dispose of Medikinet MR in the environment, such as in a wastewater pipe or toilet, unless instructed to do so. Consult a waste disposal company or pharmacist for advice on safe disposal methods to help protect the environment.
In conclusion, Medikinet MR is a psychotropic medication indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents, and adults diagnosed with ADHD according to DSM-IV. However, Medikinet MR may cause some unwanted side effects and drug interactions. Therefore, inform your doctor of all the medications you are using to minimize the risk of side effects and improve the effectiveness of your treatment.
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